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Now showing items 21-30 of 102
Understanding the Burden of Atopic Dermatitis in Africa and the Middle East
(
Springer Healthcare
, 2019 , Article Review)
Atopic dermatitis (AD) is a common inflammatory skin disease characterized by intensely pruritic lesions. The prevalence of atopic dermatitis is increasing in developing regions, including Africa and the Middle East. ...
Reading patterns of proteome damage by glycation, oxidation and nitration: quantitation by stable isotopic dilution analysis LC-MS/M
(
Portland Press
, 2020 , Article Review)
Liquid chromatography-tandem mass spectrometry (LC-MS/MS) provides a high sensitivity, high specificity multiplexed method for concurrent detection of adducts formed by protein glycation, oxidation and nitration, also ...
IP3 receptors and their intimate liaisons
(
Elsevier
, 2020 , Article Review)
Inositol 1,4,5-trisphosphate receptors (IP3Rs) are intracellular Ca2+ channels. They allow cell-surface receptors that stimulate IP3 formation to evoke rapid Ca2+ release from the endoplasmic reticulum (ER). IP3Rs initiate ...
Gravitational Influence on Human Living Systems and the Evolution of Species on Earth
(
MDPI
, 2021 , Article Review)
Gravity constituted the only constant environmental parameter, during the evolutionary period of living matter on Earth. However, whether gravity has affected the evolution of species, and its impact is still ongoing. The ...
Microneedles: A new generation vaccine delivery system
(
MDPI
, 2021 , Article Review)
Transdermal vaccination route using biodegradable microneedles is a rapidly progressing field of research and applications. The fear of painful needles is one of the primary reasons most people avoid getting vaccinated. ...
Comparison of immunogenicity and safety of licensed Japanese encephalitis vaccines: A systematic review and network meta-analysis
(
Elsevier
, 2021 , Article Review)
IntroductionAnnually more than 100,000 Japanese encephalitis (JE) cases and 25,000 deaths worldwide are caused by JE virus infection. More than 15 JE vaccines are currently in use worldwide. It is unknown whether any of ...
Autosomal Recessive Primary Microcephaly: Not Just a Small Brain
(
Frontiers Media
, 2022 , Article Review)
Microcephaly or reduced head circumference results from a multitude of abnormal developmental processes affecting brain growth and/or leading to brain atrophy. Autosomal recessive primary microcephaly (MCPH) is the prototype ...
SOD2, a Potential Transcriptional Target Underpinning CD44-Promoted Breast Cancer Progression
(
MDPI
, 2022 , Article Review)
CD44, a cell-adhesion molecule has a dual role in tumor growth and progression; it acts as a tumor suppressor as well as a tumor promoter. In our previous work, we developed a tetracycline-off regulated expression of CD44’s ...
Oxidative Stress-Induced Endothelial Dysfunction in Cardiovascular Diseases
(
IMR Press
, 2022 , Article Review)
Cardiovascular disease (CVD) is a major cause of mortality worldwide. A better understanding of the mechanisms underlying CVD is key for better management or prevention. Oxidative stress has been strongly implicated in the ...
Burden and disease pathogenesis of influenza and other respiratory viruses in diabetic patients
(
Elsevier
, 2022 , Article Review)
Over the past two decades, diabetes mellitus (DM) has been receiving increasing attention among autoimmune diseases. The prevalence of type 1 and type 2 diabetes has increased rapidly and has become one of the leading ...