College of Medicine: المرسلات الحديثة
السجلات المعروضة 401 -- 420 من 1509
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Proteomic Profiling of Small-Cell Lung Cancer: A Systematic Review
( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)The accurate diagnosis of small-cell lung cancer (SCLC) is crucial, as treatment strategies differ from those of other lung cancers. This systematic review aims to identify proteins differentially expressed in SCLC compared ... -
An Updated Review of the Biomarkers of Response to Immune Checkpoint Inhibitors in Merkel Cell Carcinoma: Merkel Cell Carcinoma and Immunotherapy
( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)Merkel cell carcinoma (MCC) is primarily a disease of the elderly Caucasian, with most cases occurring in individuals over 50. Immune checkpoint inhibitors (ICI) treatment has shown promising results in MCC patients. ... -
Regulatory enforcement of the marketing of fixed-dose combinations in India: a case study of systemic antibiotics
( Springer Nature , 2023 , Article)Background: In India, states have licensed the manufacture of large numbers of fixed-dose combination (FDC) drugs without the required prior approval of the central regulator. This paper describes two major regulatory ... -
Biomaterials in Traumatic Brain Injury: Perspectives and Challenges
( MDPI , 2023 , Article Review)Traumatic brain injury (TBI) is a leading cause of mortality and long-term impairment globally. TBI has a dynamic pathology, encompassing a variety of metabolic and molecular events that occur in two phases: primary and ... -
The Association Between Short Sleep Duration and Metabolic Syndrome: A Case-Control Study
( Dove Press Ltd , 2023 , Article)Purpose: Short sleep duration and quality are increasingly common in the Middle East and North Africa (MENA) region and has been linked to metabolic syndrome, which increases the risk of cardiovascular disease and diabetes. ... -
The role of Rezum in the management of refractory urinary retention due to benign prostate hyperplasia: A literature review
( Taylor and Francis Ltd. , 2023 , Article)Background: Benign prostatic hyperplasia is the most common cause of urinary retention in men (BPH). The gold standard surgical treatment is transurethral resection of the prostate (TURP). However, due to the morbidity and ... -
The impact of a universal social emotional intervention on students' mental wellbeing in a secondary public school in Qatar
( Cogent OA , 2023 , Article)This paper is based on a study that explored the impact of a practitioner-designed social emotional program on students' wellbeing based on the results of the WEMWBS scale in a public secondary school in Qatar. This cluster ... -
The Role of Demographic and Clinical Characteristics in Distinguishing Testicular Torsion from Torsion of the Appendix Testis: A Single-center Retrospective Study
( Karolinum - Nakladatelstvi Univerzity Karlovy , 2023 , Article)The acute scrotum (AS) in the pediatric population is a medical emergency. AS is usually caused by testicular torsion (TT) and torsion of the appendix testis (TAT). The current study explored which demographic and clinical ... -
Thermogenic Modulation of Adipose Depots: A Perspective on Possible Therapeutic Intervention with Early Cardiorenal Complications of Metabolic Impairment
( American Society for Pharmacology and Experimental Therapy (ASPET) , 2023 , Article)Cardiovascular complications of diabetes and obesity remain a major cause for morbidity and mortality worldwide. Despite significant advances in the pharmacotherapy of metabolic disease, the available approaches do not ... -
Trends in prescribing and outcomes in obese versus non-obese patients receiving rivaroxaban therapy: an observational study using real-world data
( Springer Science and Business Media Deutschland GmbH , 2023 , Article)Purpose To investigate real-world prescribing trends and clinical outcomes based on body mass index (BMI) categorization in patients who received rivaroxaban therapy. Methods This was a retrospective cohort study ... -
The assessment of tumor-infiltrating lymphocytes in invasive apocrine carcinoma of the breast in relation to the HER2 status.
( Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina , 2023 , Article)In the current study, we assessed the prevalence and molecular features of HER2-low phenotype in the apocrine carcinomas of the breast (ApoCa) and its relationship with tumor-infiltrating lymphocytes (TILs). A cohort of ... -
Factors associated with depression and anxiety in the adult population of Qatar after the first COVID-19 wave: a cross-sectional study
( springer , 2021 , Article)There is limited data from Arabic-speaking countries on risk factors for depression and anxiety during the COVID-19 pandemic. Country-specific data is necessary given differences in culture, demographics, and COVID-19 ... -
Trends in prevalence of depression and anxiety symptoms and effects of sociodemographic variables before and after the first wave of COVID-19 in Qatar
( Elsevier , 2022 , Article)Background Prevalence trends from Arabic speaking countries on psychiatric symptoms before and after the first wave of the COVID-19 pandemic are lacking. We estimated the point prevalence and change in depression and ... -
Validation of a risk prediction model for COVID-19: the PERIL prospective cohort study.
( Future Medicine , 2023 , Article)This study aims to perform an external validation of a recently developed prognostic model for early prediction of the risk of progression to severe COVID-19. Patients were recruited at their initial diagnosis at two ... -
Arrhythmia-Associated Calmodulin E105A Mutation Alters the Binding Affinity of CaM to a Ryanodine Receptor 2 CaM-Binding Pocket
( MDPI , 2023 , Article)Calmodulin (CaM) is a small, multifunctional calcium (Ca2+)-binding sensor that binds and regulates the open probability of cardiac ryanodine receptor 2 (RyR2) at both low and high cytosolic Ca2+ concentrations. Recent ... -
Elaeagnus Angustifolia Plant Extract inhibits Epithelial- mesenchymal Transition in Human Colorectal Cancer via β-catenin/JNK signaling Pathways
( University of Jordan,Deanship of Scientific Research , 2023 , Article)Elaeagnus angustifolia (EA) is a traditional plant that has been used as an alternative medicine for centuries. EA roles as anti-cancer has been investigated against different types of cancer, however, its effect against ... -
The role of anti-Mullerian hormone and other correlates in patients with polycystic ovary syndrome
( Taylor and Francis Ltd. , 2023 , Article)Background Anti-Müllerian hormone (AMH) has recently emerged as a promising biomarker for the detection of polycystic ovarian morphology. In polycystic ovary syndrome (PCOS), an elevated level of AMH has been suggested ... -
Toward a meta-vaccine future: Promoting vaccine confidence in the metaverse
( SAGE Publications Inc. , 2023 , Article)The metaverse has a promising role to serve as a global platform and tackle one of the most intractable public health challenges; vaccine hesitancy. Active efforts in this field can enhance vaccine acceptance thus leading ... -
RamanNet: a generalized neural network architecture for Raman spectrum analysis
( Springer Science and Business Media Deutschland GmbH , 2023 , Article)Raman spectroscopy provides a vibrational profile of the molecules and thus can be used to uniquely identify different kinds of materials. This sort of molecule fingerprinting has thus led to the widespread application of ... -
Serum NMR-Based Metabolomics Profiling Identifies Lipoprotein Subfraction Variables and Amino Acid Reshuffling in Myeloma Development and Progression
( MDPI , 2023 , Article)Multiple myeloma (MM) is an incurable hematological cancer. It is preceded by monoclonal gammopathy of uncertain significance (MGUS)—an asymptomatic phase. It has been demonstrated that early detection increases the 5-year ...
