College of Medicine: Recent submissions
Now showing items 161-180 of 1508
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Optimizing cancer therapy: a review of the multifaceted effects of metronomic chemotherapy
( Frontiers Media , 2024 , Article Review)Metronomic chemotherapy (MCT), characterized by the continuous administration of chemotherapeutics at a lower dose without prolonged drug-free periods, has garnered significant attention over the last 2 decades. Extensive ... -
Genomic Newborn Screening for Pediatric Cancer Predisposition Syndromes: A Holistic Approach
( MDPI , 2024 , Article Review)As next-generation sequencing (NGS) has become more widely used, germline and rare genetic variations responsible for inherited illnesses, including cancer predisposition syndromes (CPSs) that account for up to 10% of ... -
Reinventing Patient Support and Continuity of Care Using Innovative Physician-staffed Hotline: More than 60,000 Patients Served Across 15 Medical and Surgical Specialties During the First Wave of COVID-19 Lockdown in Qatar
( Springer Nature , 2023 , Article)Rising disease prevalence early during the COVID-19 pandemic in the State of Qatar led to stoppage of all non-emergency health care services. To maintain continuity of care and information exchanges for non-emergency ... -
“Is percutaneous extraction of gallstones safe and effective in high-risk patients? Evidence from a systematic review”
( Elsevier , 2022 , Article)Gallstone disease in high-risk patients presents a management dilemma as cholecystectomy is often not performed due to their co-morbidities. Alternatively, such patients can be managed by percutaneous removal of gallstones. ... -
Urinary guide-wire and Tritube solved the mystery of severe tracheal stenosis management: A case report
( Elsevier , 2023 , Article)Patients with tracheal stenosis may exhibit various signs and symptoms of respiratory compromise, depending on the degree of stenosis. Proper identification and prompt intervention are crucial to ensure the best possible ... -
Subclavian pseudoaneurysm presenting as partially obstructed airway
(2023 , Article)We are presenting a noteworthy instance of managing the airway of a patient who had acute tracheal stenosis of considerable magnitude caused by external compression resulting from a large right subclavian pseudoaneurysm.Tracheal ... -
Non-Participatory Observation Of Integrated Management Of Childhood Illness Practices At Selected Basic Health Units Of District Abbottabad, Kp, Pakistan: A Qualitative Hermeneutic Study
( Ayub Medical College , 2023 , Article)BACKGROUND: It was in 1995 when a strategy was devised to reduce under-five mortality in countries with a prevalence of child mortality above 40/1000 live births. This strategy is called "Integrated Management of Childhood ... -
Bioelectrical Impedance Analysis Detects Body Fat Changes After Surgical Subcutaneous Fat Removal
( Mary Ann Liebert , 2024 , Article)Background: The risk and metabolic effects of obesity are determined by the distribution of fat throughout the body. It has been proposed that the distribution of abdominal fat is more closely related to the metabolic risks ... -
Ventilator-associated pneumonia diagnosis: electrochemical sensors for rapid and sensitive detection of pyocyanin
( Springer Nature , 2024 , Article)Ventilator-associated pneumonia (VAP) is a severe condition in critically ill patients that requires timely diagnosis to improve patient outcomes. In this study, we developed an electrochemical sensor for pyocyanin detection ... -
Comprehensive molecular and clinical insights into non-small cell lung cancer transformation to small cell lung cancer with an illustrative case report
( Taylor & Francis , 2024 , Article)Histologic transformation to small cell lung cancer (tSCLC) is a rare but increasingly recognised mechanism of acquired resistance to tyrosine kinase inhibitors (TKI) in patients with epidermal growth factor receptor ... -
Perspectives of healthcare workers on integrated management of childhood illness in Pakistan: A phenomenological approach
( SAGE , 2024 , Article)In 2019, an estimated 5.2 million deaths were reported among children less than 5 years of age. At primary healthcare level, healthcare workers (HCWs) mostly rely on history and clinical findings and less on inadequate ... -
Low levels of Vitamin D during pregnancy associated with gestational diabetes mellitus and low birth weight: results from the MAASTHI birth cohort
( Frontiers Media , 2024 , Article)Introduction: India has a high prevalence of Vitamin D insufficiency among women of childbearing age. In this study, we aimed to evaluate the potential relationship between Vitamin D deficiency and gestational diabetes ... -
Development of Recombinant PLC-Zeta Protein as a Therapeutic Intervention for the Clinical Treatment of Oocyte Activation Failure
( MDPI , 2024 , Article)The sperm-specific phospholipase C zeta (PLCζ) protein is widely considered as the predominant physiological stimulus for initiating the Ca2+ release responsible for oocyte activation during mammalian fertilization. The ... -
The relationship between oxidative stress and apoptosis of histopathological changes in the ovary made by mad honey containing grayanotoxin
( Elsevier , 2024 , Article)The purpose of this study is to determine the effects of grayanotoxin in mad honey on ovarian tissue folliculogenesis in terms of cell death and nitric oxide expression. Three groups of 18 female Sprague-Dawley rats were ... -
Injuries related to pets, exotic animals, and falconry in Qatar
( HBKU Press , 2023 , Article)Introduction: Pets and exotic animals are increasingly popular all over the world. Some of these animals may cause injuries to their owners or other people during interactions. Both injuries and systemic infections always ... -
The cost associated with the development of the antimicrobial stewardship program in the adult general medicine setting in Qatar
( Taylor and Francis Ltd. , 2024 , Article)Objective: To estimate the economic impact of the developed antimicrobial stewardship program (ASP) versus the preliminary ASP use, in the adults' general medicine settings in Qatar. Methods: Patient records were retrospectively ... -
Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021
( Elsevier , 2024 , Article)BackgroundFuture trends in disease burden and drivers of health are of great interest to policy makers and the public at large. This information can be used for policy and long-term health investment, planning, and ... -
Prevalence of dyslipidemia, hypertension and diabetes among tribal and rural population in a south Indian forested region.
( Public Library of Science , 2024 , Article)While NCDs are in rise globally, tribal and rural populations residing near to reserve forests with limited exposure to modern lifestyles may bear a unique burden. This study investigates the prevalence and risk factors ... -
SARS-CoV-2 infection triggers more potent antibody-dependent cellular cytotoxicity (ADCC) responses than mRNA-, vector-, and inactivated virus-based COVID-19 vaccines
( Wiley , 2024 , Article)Neutralizing antibodies (NAbs) are elicited after infection and vaccination and have been well studied. However, their antibody-dependent cellular cytotoxicity (ADCC) functionality is still poorly characterized. Here, we ... -
Follow-Up and Comparative Assessment of SARS-CoV-2 IgA, IgG, Neutralizing, and Total Antibody Responses After BNT162b2 or mRNA-1273 Heterologous Booster Vaccination
( Wiley , 2024 , Article)Background: Priming with ChAdOx1 followed by heterologous boosting is considered in several countries. Nevertheless, analyses comparing the immunogenicity of heterologous booster to homologous primary vaccination regimens ...
