College of Medicine: Recent submissions
Now showing items 181-200 of 1508
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Pathogenic Homocystinuria-Associated T236N Mutation Dramatically Alters the Biochemical Properties of Cystathionine Beta-Synthase Protein
( MDPI , 2024 , Article)Background: Cystathione beta-synthase (CBS) T236N is a novel mutation associated with pyridoxine non-responsiveness, which presents a significant difficulty in the medical treatment of homocystinuria. Reported severe ... -
Antibody-dependent enhancement (ADE) of SARS-CoV-2 in patients exposed to MERS-CoV and SARS-CoV-2 antigens
( Wiley , 2024 , Article)This study evaluated the potential for antibody-dependent enhancement (ADE) in serum samples from patients exposed to Middle East respiratory syndrome coronavirus (MERS-CoV). Furthermore, we evaluated the effect of severe ... -
Cranial measurements obtained by three-dimensional computed tomography technique in the estimation of sex of contemporary Black South Africans
( Elsevier , 2024 , Article)Human identification forms an integral part of forensic and biological anthropology. For proper identification, a biological profile made up of biodata such as age, sex, ancestry, antemortem stature, and factors of ... -
BRCA1 and Its Vulnerable C-Terminal BRCT Domain: Structure, Function, Genetic Mutations and Links to Diagnosis and Treatment of Breast and Ovarian Cancer
( Multidisciplinary Digital Publishing Institute (MDPI) , 2024 , Article)The BRCA1 is a tumor suppressor gene that encodes for the BRCA1 protein, which plays a vital role in DNA repair, cell cycle regulation, and the maintenance of genomic stability. The BRCA1 protein interacts with a variety ... -
Efficacy and Clinical Outcomes of mRNA COVID-19 Vaccine in Pregnancy: A Systematic Review and Meta-Analysis
( S. Karger AG , 2024 , Article)BACKGROUND: The world has witnessed one of the largest pandemics, dubbed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). As of December 2020, the USA alone reported 98,948 cases of coronavirus disease 2019 ... -
Effectiveness of locally produced ready-to-use supplementary foods on the prevention of stunting in children aged 6-23 months: A community-based trial from Pakistan
( Cambridge University Press , 2023 , Article)Undernutrition is a major public health problem in developing countries. Around 40·2 % of children are stunted in Pakistan. This longitudinal study aimed to assess the effectiveness of locally produced ready-to-use ... -
Biochemical and structural impact of two novel missense mutations in cystathionine β-synthase gene associated with homocystinuria
( Portland Press Ltd , 2024 , Article)Homocystinuria is a rare disease caused by mutations in the CBS gene that results in a deficiency of cystathionine β-synthase (CBS). CBS is an essential pyridoxal 50-phosphate (PLP)-dependent enzyme in the transsulfuration ... -
Bariatric Surgery Improves Serum CD40L Levels as a Predictor of Cardiovascular Risk: Systematic Review and Meta-analysis
(2024 , Article)CD40 and its ligand have been recently implicated in the pathogenesis of cardiovascular disease (CVD). This meta-analysis examined the effect of bariatric surgery in reducing circulating CD40L levels. A systematic review ... -
Tranexamic Acid for Traumatic Injury in the Emergency Setting: A Systematic Review and Bias-Adjusted Meta-Analysis of Randomized Controlled Trials
( Elsevier , 2024 , Article)Study objectiveTraumatic injury causes a significant number of deaths due to bleeding. Tranexamic acid (TXA), an antifibrinolytic agent, can reduce bleeding in traumatic injuries and potentially enhance outcomes. Previous ... -
Bi-attention DoubleUNet: A deep learning approach for carotid artery segmentation in transverse view images for non-invasive stenosis diagnosis
( Elsevier , 2024 , Article)The carotid artery is a vital blood vessel that supplies oxygenated blood to the brain. Blockages in this artery can lead to life-threatening illnesses, making accurate diagnosis essential. While ultrasound (US) imaging ... -
Second round statewide sentinel-based population survey for estimation of the burden of active infection and anti-SARS-CoV-2 IgG antibodies in the general population of Karnataka, India, during January-February 2021
( Elsevier , 2024 , Article)Objective Demonstrate the feasibility of using the existing sentinel surveillance infrastructure to conduct the second round of the serial cross-sectional sentinel-based population survey. Assess active infection, ... -
Eagle syndrome an overlooked cause of internal carotid artery dissection, Case series
( Elsevier , 2024 , Article)Background: Eagle syndrome is a rare condition with a prevalence estimated at 4%, with 0.16% exhibiting symptoms of Eagle's syndrome resulting from an elongated styloid process or a calcified stylohyoid ligament, compressing ... -
An overview of diabetes mellitus in pregnant women with obesity
( Elsevier , 2024 , Article Review)Rates of obesity are increasing world-wide with an estimated 1billion people projected to be obese by 2030 if current trends remain unchanged. Obesity currently considered one of the most significant associated factors of ... -
Corrigendum to "Second round statewide sentinel-based population survey for estimation of the burden of active infection and anti-SARS-CoV-2 IgG antibodies in the general population of Karnataka, India, during January-February 2021" [IJID Regions Vol 1(2021) pages 107-116]
( Elsevier , 2024 , Article)The authors regret the affiliation correction of Dr. Giridhara R. Babu. The correct affiliation should be amended to read as follows: Giridhara R Babu, Department of Population Medicine, College of Medicine, QU Health, ... -
Physicians should build their own machine-learning models
( Elsevier , 2024 , Article)Yosra Mekki suggests that doctors should have the ability to develop their own machine-learning models. She proposes an approach with the "spotlight" on physicians, to create user-friendly frameworks that allow doctors to ... -
Best practice and research clinical obstetrics and gynaecology volume 92
( Elsevier , 2024 , Other)Obesity is rising world-wide and has become the most common risk factor for non-communicable diseases. The increase is disproportionate, being higher in the low- and middle-income countries compared to high-income countries. ... -
Corrigendum to “Suicide during pandemic requires deeper engagement” [Asian J. Psychiatry 73 (2022) 103161]
( Elsevier , 2024 , Article)The authors regret < During the submission, review, and publication stages of this article, Dr Giridhar R Babu was affiliated with Qatar University. Unfortunately, due to a transitional phase in his career, this critical ... -
Preface : Best Practice & Research Clinical Obstetrics & Gynaecology
( Elsevier , 2024 , Other)Obesity defined as BMI ≥30 kg/m2 is now considered one of the most important contributors to the rising morbidity and mortality world-wide from non-communicable diseases and by implication cost of healthcare. The WHO ... -
Best practice and research clinical obstetrics and gynaecology volume 92
( Elsevier , 2024 , Other)Obesity is rising world-wide and has become the most common risk factor for non-communicable diseases. The increase is disproportionate, being higher in the low- and middle-income countries compared to high-income countries. ... -
Fetal holoprosencephaly
( Jaypee Brothers Medical Publishers (P) Ltd , 2020 , Article)Holoprosencephaly is a birth defect that leads to an abnormal brain development where the brain fails to divide into two hemispheres. Possible causes are environmental or genetic factors. Holoprosencephaly can include ...
