College of Pharmacy: Recent submissions
Now showing items 281-300 of 1280
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Cisplatin-induced ototoxicity: A novel approach to an ancient problem
( Lippincott, Williams & Wilkins , 2023 , Article)With the scarcity of pharmacological otoprotective agents against cisplatin-induced ototoxicity (CIO), researchers find themselves compelled to look at and navigate all possible strategies to identify ways to prevent CIO. ... -
Genetic Factors Associated with Morphine Consumption in Women Undergoing Laparoscopic Cholecystectomy: A Prospective Cohort Study.
( Dove Press Ltd , 2023 , Article)Morphine has been a crucial analgesic agent used perioperatively in various surgical procedures. Genetic factors can lead to morphine dose requirement interpatient variability. Our objective was to determine the contribution ... -
Recommendations for wider adoption of clinical pharmacy in Central and Eastern Europe in order to optimise pharmacotherapy and improve patient outcomes
( Frontiers Media , 2023 , Article)Clinical pharmacy as an area of practice, education and research started developing around the 1960s when pharmacists across the globe gradually identified the need to focus more on ensuring the appropriate use of medicines ... -
Awareness of the risk factors for heart attack among the general public in pahang, malaysia: A cross-sectional study
( Dove Medical Press , 2020 , Article)Background: Cardiovascular disease is a leading nationwide cause of morbidity and mortality. Public awareness of risk factors for heart attacks is thought to impact the burden of disease, prevention, and timely management. ... -
An exploratory analysis of the portrayal of mental illness in Qatar’s newspapers
( Dove Medical Press , 2020 , Article)Background: Concerns have been raised about the role of the media influencing the public’s understanding of mental illness. Aim: This study explored the extent and nature of mental health coverage in Qatar’s newspapers. A ... -
Pharmacological and antioxidant activities of rhus coriaria l. (sumac)
( Multidisciplinary Digital Publishing Institute (MDPI) , 2021 , Article)Rhus coriaria L. (Anacardiaceae), commonly known as sumac, is a commonly used spice, condiment, and flavoring agent, especially in the Mediterranean region. Owing to its bountiful beneficial values, sumac has been used in ... -
Genetic polymorphism effect on warfarin–rifampin interaction: A case report and review of literature
( Dove Medical Press , 2021 , Article)Warfarin–rifampin interaction has been reported since the 1970s. Due to rifampin’s strong induction of CYP2C9, most cases could not attain the target international normalized ratio (INR) despite warfarin dose escalation. ... -
COVID-19 vaccination: From interesting agent to the patient
( Multidisciplinary Digital Publishing Institute (MDPI) , 2021 , Article)The vaccination for the novel Coronavirus (COVID-19) is undergoing its final stages of analysis and testing. It is an impressive feat under the circumstances that we are on the verge of a potential breakthrough vaccination. ... -
Managing Pain in Low Resource Settings: Healthcare Professionals’ Knowledge, Attitude and Practice Regarding Pain Management in Western Nepal
( Dove Medical Press Ltd , 2022 , Article)Background: Pain is a public health problem and affects millions of people globally. Effective pain management is possible through comprehensive pain management guidelines, adequate facilities, and trained healthcare ... -
Long-acting injectable antipsychotics: A systematic review of their non-systemic adverse effect profile
( Dove Medical Press , 2021 , Article)Introduction: Long acting injectable (LAI) antipsychotics are commonly used in the treatment of schizophrenia to improve adherence and clinical outcomes. Concerns have been reported in relation to their non-systemic or ... -
Pharmacokinetics and tissue distribution of an orally administered mucoadhesive chitosan-coated amphotericin B-Loaded nanostructured lipid carrier (NLC) in rats
( Taylor and Francis Inc. , 2020 , Article)Oral delivery of amphotericin B (AmpB) is desirable because it provides a more patient-friendly mode of administration compared to the current delivery approach akin with the marketed AmpB formulations. The goal of the ... -
Soliciting the Oral Route as a Logical Approach to Managing Colon Cancer
( Frontiers Media S.A. , 2021 , Article)According to Global Cancer Incidence, Mortality and Prevalence (GLOBOCAN) 2018, colon cancer (CC) is the third most common cancer in men and second in women worldwide (Bray et al., 2018). Approximately 1.8 million new colon ... -
Solid Dispersion Formulations by FDM 3D Printing—A Review
( MDPI , 2022 , Article)Additive manufacturing (AM) is revolutionizing the way medicines are designed, manufactured, and utilized. Perhaps, AM appears to be ideal for the fit-for-purpose manufacturing of medicines in contrast to the several ... -
Curcumin and Derivatives in Nanoformulations with Therapeutic Potential on Colorectal Cancer
( Springer Science and Business Media Deutschland GmbH , 2022 , Article)There is growing concern in the rise of colorectal cancer (CRC) cases globally, and with this rise is the presentation of drug resistance. Like other cancers, current treatment options are either invasive or manifest severe ... -
The types and pattern of use of mobile health applications among the general population: A cross-sectional study from Selangor, Malaysia
( Dove Medical Press , 2021 , Article)Purpose: The aims of this study are to explore the types and patterns of use of health mobile apps among pharmacy clients in Selangor, Malaysia, and to explore the users’ experiences and views regarding the benefits of and ... -
Genetic and non-genetic factors impact on inr normalization in preprocedural warfarin management
( Dove Medical Press , 2021 , Article)Background: Annually, 10% of warfarin patients will likely need to stop warfarin prior to elective surgery to achieve a baseline international normalization ratio (INR) level (INR ≤ 1.2) at the time of the procedure. This ... -
An evaluation of tocotrienol ethosomes for transdermal delivery using Strat-M® membrane and excised human skin
( Taylor and Francis Ltd. , 2021 , Article)Tocotrienol (TRF) ethosomes were developed and evaluated in vitro for potential transdermal delivery against melanoma. The optimised TRF ethosomal size ranged between 64.9 ± 2.2 nm to 79.6 ± 3.9 nm and zeta potential (ZP) ... -
Lyophilized drug-loaded solid lipid nanoparticles formulated with beeswax and theobroma oil
( MDPI AG , 2021 , Article)Solid lipid nanoparticles (SLNs) have the potential to enhance the systemic availability of an active pharmaceutical ingredient (API) or reduce its toxicity through uptake of the SLNs from the gastrointestinal tract or ... -
Mechanisms of amyloid proteins aggregation and their inhibition by antibodies, small molecule inhibitors, nano-particles and nano-bodies
( Elsevier , 2021 , Article)Protein misfolding and aggregation can be induced by a wide variety of factors, such as dominant disease-associated mutations, changes in the environmental conditions (pH, temperature, ionic strength, protein concentration, ... -
Improved bioavailability of poorly soluble drugs through gastrointestinal muco-adhesion of lipid nanoparticles
( Multidisciplinary Digital Publishing Institute (MDPI) , 2021 , Article)Gastrointestinal absorption remains indispensable in the systemic delivery of most drugs, even though it presents several challenges that, paradoxically, may also provide opportunities that can be exploited to achieve ...