College of Pharmacy: Recent submissions
Now showing items 281-300 of 1384
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Deciphering the complexities of cancer cell immune evasion: Mechanisms and therapeutic implications
( Elsevier , 2023 , Article Review)Cancer immune evasion is one of the principal mechanisms leading to the progression and metastatization of the disease. Despite the migration and infiltration at the tumor site of immune cells, multiple factors can influence ... -
Protein tyrosine phosphatase 1B inhibition improves endoplasmic reticulum stress-impaired endothelial cell angiogenic response: A critical role for cell survival
( Spandidos publications , 2021 , Article)Endoplasmic reticulum (ER) stress contributes to endothelial dysfunction, which is the initial step in atherogenesis. Blockade of protein tyrosine phosphatase (PTP)1B, a negative regulator of insulin receptors that is ... -
Mental Health Prescribers' Perceptions on the Use of Pharmacogenetic Testing in the Management of Depression in the Middle East and North Africa Region
( Dove Medical Press Ltd , 2023 , Article)Objective: A wide variety of commercial pharmacogenetic (PGx) tools are available worldwide to guide treatment selection for depression based on individuals’ genetic profiles. However, the use of genetic testing to inform ... -
Sleep Quality and Sleep Hygiene Behaviours Among University Students in Qatar
( Dove Medical Press Ltd , 2023 , Article)Background: Insomnia is a highly prevalent health problem, affecting about one-third of the adult population globally. University students are at a high risk for developing insomnia due to the stressful nature of academic ... -
Serum immune mediators as novel predictors of response to anti-PD-1/PD-L1 therapy in non-small cell lung cancer patients with high tissue-PD-L1 expression
( Frontiers Media S.A. , 2023 , Article)Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related morbidity and mortality worldwide. Immune checkpoint inhibitors (ICIs) including anti-PD-1 and anti-PD-L1 antibodies, have significantly changed the ... -
Deep Learning Technique for Congenital Heart Disease Detection Using Stacking-Based CNN-LSTM Models from Fetal Echocardiogram: A Pilot Study
( IEEE , 2023 , Article)Congenital heart defects (CHDs) are a leading cause of death in infants under 1 year of age. Prenatal intervention can reduce the risk of postnatal serious CHD patients, but current diagnosis is based on qualitative criteria, ... -
Percutaneous Mitral-Valve Intervention for Secondary Mitral Regurgitation: Data From Real-Life
( Elsevier , 2023 , Article Review)Many questions were raised due to the divergent results between cardiovascular outcomes assessment of the MitraClip percutaneous therapy for heart failure patients with functional mitral regurgitation (COAPT) and multicenter ... -
Nanotargeted Delivery of Immune Therapeutics in Type 1 Diabetes
( John Wiley and Sons Inc , 2023 , Article)Immune therapeutics holds great promise in the treatment of type 1 diabetes (T1D). Nonetheless, their progress is hampered by limited efficacy, equipoise, or issues of safety. To address this, a novel and specific nanodelivery ... -
Pill-burden and its association with treatment burden among patients with advanced stages of chronic kidney disease
( Elsevier , 2023 , Article)Introduction: Chronic kidney disease (CKD) is associated with multimorbidity and high treatment burden. Pill-burden is one component of the overall treatment burden. However, little is known about its magnitude and ... -
Inappropriate polypharmacy management versus deprescribing: A review on their relationship
( John Wiley and Sons Inc , 2023 , Article Review)Medication burden and polypharmacy are highly prevalent among patients with multimorbidity. There have been multiple initiatives to overcome polypharmacy and medication burden in patients with multimorbidity. These initiatives ... -
Economic impact of clinical pharmacist interventions in a general tertiary hospital in Qatar
( Public Library of Science , 2023 , Article)Background With an increasingly strained health system budgets, healthcare services need to continually demonstrate evidence of economic benefits. This study sought to evaluate the economic impact of interventions initiated ... -
Impact of Clinical Pharmacist Interventions on Economic Outcomes in a Cardiology Setting in Qatar
( Elsevier , 2023 , Article)We sought to investigate the economic impact of preventing adverse events in a cardiology setting in Qatar as an effect of the clinical pharmacist as an intervention. This is a retrospective study of interventions by ... -
The impact of molecular tumor profiling on the design strategies for targeting myeloid leukemia and EGFR/CD44-positive solid tumors
(2021 , Article)Nanomedicine has emerged as a novel cancer treatment and diagnostic modality, whose design constantly evolves towards increasing the safety and efficacy of the chemotherapeutic and diagnostic protocols. Molecular diagnostics, ... -
Influence of the Extraction Solvent and of the Altitude on the Anticancer Activity of Lebanese Eucalyptus camaldulensis Extract Alone or in Combination with Low Dose of Cisplatin in A549 Human Lung Adenocarcinoma Cells
( MDPI , 2022 , Article)Background: Lung cancer is the second most common cancer worldwide. Eucalyptus plant extract has been shown to have anti-neoplastic effects. We investigated the antitumor effect of ethanolic and aqueous extracts of Eucalyptus ... -
Comparative efficacy and safety among high-intensity statins. Systematic Review and Meta-Analysis
( Becaris Publishing , 2023 , Article)Aim: To summarize the evidence in terms of efficacy and safety of head-to-head studies of high-intensity statins regardless of the underlying population. Materials & methods: A systematic review and meta-analysis was ... -
A systematic meta-ethnographic review of the beneficial outcomes of international internships to student pharmacists
( AACP , 2017 , Article)Objective. To describe the benefits that pharmacy students gain by completing international internships as a part of their pharmacy education. Methods. A systematic literature search was conducted from database inception ... -
Contemporary professional skills development for pharmacists in the middle east
( AACP , 2017 , Article)Objective. To determine professional skills development and its utility among the “bridge” curriculum for undergraduate and graduate students in the Middle East. Methods. Qatar University College of Pharmacy offers a ... -
Targeting cancer signaling pathways by natural products: Exploring promising anti-cancer agents
( Elsevier , 2022 , Article Review)Cancer is one of the leading causes of death and significantly burdens the healthcare system. Due to its prevalence, there is undoubtedly an unmet need to discover novel anticancer drugs. The use of natural products as ... -
Perceptions of Yemeni physicians about sources of drug information and factors predicting their choices
( Open Science Publishers LLP , 2021 , Article)High-quality information is a necessary prerequisite for an optimum prescribing decision that enhances patient healthcare outcomes. Therefore, the purpose of this study was to identify the main sources of information used ... -
Improving the quality of publications in and advancing the paradigms of clinical and social pharmacy practice research: The Granada statements
( springer link , 2023 , Article)Pharmacy and pharmaceutical sciences embrace a series of different disciplines. Pharmacy practice has been defined as “the scientific discipline that studies the different aspects of the practice of pharmacy and its impact ...