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المؤلفAbdallah, Bushra
المؤلفArif, Mariah
المؤلفAl-Malki, Maryam
المؤلفHourani, Razan
المؤلفAl-Maadeed, Tamader
المؤلفKhodr, Nidal
المؤلفAl-Kuwari, Ghaith
المؤلفAl-Siddiqi, Mashael
المؤلفKane, Tanya
المؤلفChivese, Tawanda
تاريخ الإتاحة2023-05-24T10:33:02Z
تاريخ النشر2023-01-21
اسم المنشورInternational Journal of General Medicine
المعرّفhttp://dx.doi.org/10.2147/IJGM.S393284
الاقتباسAbdallah, B., Arif, M., Al-Malki, M., Hourani, R., Al-Maadeed, T., Khodr, N., ... & Chivese, T. (2023). The Association Between Inflammatory Bowel Disease and Exposure to Tobacco Smoking: A Case-Control Study in Qatar. International Journal of General Medicine, 233-242.
الرقم المعياري الدولي للكتاب1178-7074
معرّف المصادر الموحدhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85146816376&origin=inward
معرّف المصادر الموحدhttp://hdl.handle.net/10576/43439
الملخصObjective: This research investigated the association between childhood and adulthood tobacco smoking exposure with ulcerative colitis (UC) and Crohn’s disease (CD) in Qatar. Study Design and Setting: In this case-control study, CD and UC cases were matched to controls of the same age and sex. The associations between UC and CD and childhood passive smoking and adulthood active smoking were assessed using conditional multivariable logistic regression. Results: A total of 89 CD cases, median age of 37 years (IQR 29–47), and 362 UC cases, median age of 35 years (IQR 28–44), and equal numbers of controls were included. After multivariable logistic regression, CD was associated with higher odds of being a current smoker (OR 2.51, 95% CI 0.85–7.37, p=0.095), with weak evidence against the null hypothesis. This association was more pronounced in women, where CD was associated with both adulthood current smoking (OR 42.71, 95% CI, 1.17–1559.57, p=0.041), and childhood smoking exposure (OR 8.23, 95% CI, 1.36–49.66, p=0.021). In males, no associations were observed between CD and the smoking exposures. No associations were observed between UC and both smoking variables. Conclusion: In Qatar, adulthood tobacco smoking appears to increase the odds of CD. Further, our findings suggest that both childhood and adulthood cigarette smoke exposure may possibly have a detrimental effect on the odds of CD in females but not in males, although further research is needed.
اللغةen
الناشرDove Medical Press
الموضوعchildhood passive smoking
Crohn’s disease
inflammatory bowel disease
Middle East and North Africa
smoking
ulcerative colitis
العنوانThe Association Between Inflammatory Bowel Disease and Exposure to Tobacco Smoking: A Case-Control Study in Qatar
النوعArticle
الصفحات233-242
رقم المجلد16
dc.accessType Open Access


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