Browsing Biomedical Research Center Research by Author "Sohail, Muhammad Umar"
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Comparative Phylogenetic and Residue Analysis of Hepatitis C Virus E1 Protein from the Middle East and North Africa Region
Sohail, Muhammad Umar; Hadi Muhamad, Yassine; Asma A, Al Thani ( Kowsar (Research Center for Gastroenterology and Liver Diseases, Tehran, Iran) , 2019 , Article)Hepatitis C virus (HCV) is a major public health problem in the Middle East and North Africa (MENA) region with an estimate of over 15 million chronically infected patients. However, molecular characterization of circulating ... -
Detection of paracetamol as substrate of the gut microbiome
Mukhtar, Imran; Anwar, Haseeb; Hussain, Ghulam; Rasul, Azhar; Naqvi, Syed Ali Raza; Faisal, Muhammad Naeem; Mustafa, Imtiaz; Malik, Saima; Shaukat, Arslan; Mirza, Osman Asghar; Sohail, Muhammad Umar... more authors ... less authors ( Pakistan Journal of Pharmaceutical Sciences , 2019 , Article)Gut microbiome, a new organ; represent targets to alter pharmacokinetics of orally administered drugs. Recently, in vitro trials endorsed the idea that orally administered drugs interact and some of their quantity may be ... -
The Effects of Gum Acacia on the Composition of the Gut Microbiome and Plasma Levels of Short-Chain Fatty Acids in a Rat Model of Chronic Kidney Disease
Al-Asmakh, Maha; Sohail, Muhammad Umar; Al-Jamal, Ola; Shoair, Banan Mosaad; Al-Baniali, Asmaa Yousef; Bouabidi, Salma; Nasr, Shahd; Bawadi, Hiba... more authors ... less authors ( Frontiers Media , 2020 , Article)Chronic kidney disease (CKD) may be fatal for its victims and is an important long-term public health problem. The complicated medical procedures and diet restrictions to which patients with CKD are subjected alter the gut ... -
Efficacy of Euphorbia helioscopia in context to a possible connection between antioxidant and antidiabetic activities: a comparative study of different extracts
Mustafa, Imtiaz; Faisal, Muhammad Naeem; Hussain, Ghulam; Muzaffar, Humaira; Imran, Muhammad; Ijaz, Muhammad Umar; Sohail, Muhammad Umar; Iftikhar, Arslan; Shaukat, Arslan; Anwar, Haseeb... more authors ... less authors ( Springer Nature , 2021 , Article)Background: Euphorbia helioscopia, conventionally known as sun spurge, has been used as a traditional medicine to treat different diseases owing to its reported antitumor, antiviral and antioxidant activities. Methods: The ... -
Sulpiride Serves, a Substrate for the Gut Microbiome
Mukhtar, Imran; Anwar, Haseeb; Mirza, Osman Asghar; Ali, Qasim; Ijaz, Muhammad Umar; Hume, Michael; Prabhala, Bala Krishna; Iftikhar, Arslan; Hussain, Ghulam; Sohail, Muhammad Umar; Khan, Kashif ur Rehman... more authors ... less authors ( International Dose-Response Society , 2021 , Article)In the contemporary research world, the intestinal microbiome is now envisioned as a new body organ. Recently, the gut microbiome represents a new drug target in the gut, since various orthologues of intestinal drug ...