Browsing Biomedical Research Center Research by Title
Now showing items 505-524 of 733
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Pharmacometabolomic Approach to Investigate the Response to Metformin in Patients with Type 2 Diabetes: A Cross-Sectional Study
( MDPI , 2023 , Article)Metformin constitutes the foundation therapy in type 2 diabetes (T2D). Despite its multiple beneficial effects and widespread use, there is considerable inter-individual variability in response to metformin. Our objective ... -
Phenolic contents-based assessment of therapeutic potential of Syzygium cumini leaves extract
( Public Library of Science , 2019 , Article)Syzygium cumini (S. cumini) is an evergreen tropical plant that is well recognized for its therapeutic potential of common diseases. In this study, the therapeutic potential and biomedical application of S. cumini are ... -
Phytochemicals as Micronutrients: What Is their Therapeutic Promise in the Management of Alzheimer’s Disease?
( Springer Singapore , 2022 , Book chapter)Alzheimer’s disease (AD) is a debilitating neurodegenerative disease with devastating outcomes to patients and exhaustive burdens to healthcare systems. Alzheimer’s disease has always been the focus of extensive research ... -
Phytochemicals as Micronutrients: What Is their Therapeutic Promise in the Management of Traumatic Brain Injury?
( Springer Singapore , 2022 , Book chapter)Traumatic brain injury (TBI) is one of the key causes of deaths and disabilities worldwide. TBI progresses in two phases. The primary phase of injury is the direct result of the physical damage caused by the external force ... -
Plasmid-mediated colistin resistance encoded by mcr-1 gene in Escherichia coli co-carrying blaCTX-M-15 and blaNDM-1 genes in pediatric patients in Qatar
( Elsevier , 2020 , Other)Plasmid-mediated colistin resistance encoded by mcr-1 gene in Escherichia coli co-carrying blaCTX-M-15 and blaNDM-1 genes in pediatric patients in Qatar -
Plasmonic gold nanoparticles: Optical manipulation, imaging, drug delivery and therapy
( Elsevier B.V. , 2019 , Article Review)Over the past two decades, the development of plasmonic nanoparticle (NPs), especially gold (Au) NPs, is being pursued more seriously in the medical fields such as imaging, drug delivery, and theranostic systems. However, ... -
Platelets as a Possible Reservoir of HCV And Predictor of Response to Treatment
( SciTechnol , 2016 , Article)In the era of new Hepatitis C Virus (HCV) therapy, and the detection of extrahepatic HCV reservoirs such as peripheral blood mononuclear cells and platelets, it is important to understand the factors underlying resistance ... -
Platforms Exploited for SARS-CoV-2 Vaccine Development.
( MDPI , 2020 , Article Review)The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the only zoonotic-origin coronavirus (CoV) that has reached the pandemic stage. The virus uses its spike (S) glycoprotein to attach to the host cells ... -
Poly(lactic-co-glycolic acid) Nanoparticles Loaded with Callistemon citrinus Phenolics Exhibited Anticancer Properties against Three Breast Cancer Cell Lines
( Hindawi Limited , 2019 , Article)Fruit and vegetable diets rich in phenolic compounds reduce the risk of various cancers and offer multiple other health benefits due to their bioactivity and powerful antioxidant properties. However, the human health ... -
Polymerase chain reaction ribotyping of Clostridium difficile isolates in Qatar: a hospital-based study
( BioMed Central Ltd. , 2014 , Article)Background Clostridium difficile infection (CDI) is not generally reported to public health authorities in the Middle East and its true prevalence remains largely unknown. The aims of this study were to determine the ... -
Population immunity of natural infection, primary-series vaccination, and booster vaccination in Qatar during the COVID-19 pandemic: an observational study
( Elsevier , 2023 , Article)BackgroundWaning of natural infection protection and vaccine protection highlight the need to evaluate changes in population immunity over time. Population immunity of previous SARS-CoV-2 infection or of COVID-19 vaccination ... -
Potential of Stem Cell-Based Therapy for Ischemic Stroke.
( Frontiers Media , 2018 , Article Review)Ischemic stroke is one of the major health problems worldwide. The only FDA approved anti-thrombotic drug for acute ischemic stroke is the tissue plasminogen activator. Several studies have been devoted to assessing the ... -
Pre-fusion structure of a human coronavirus spike protein
( Nature Publishing Group , 2015 , Article)HKU1 is a human betacoronavirus that causes mild yet prevalent respiratory disease1, and is related to the zoonotic SARS2 and MERS3 betacoronaviruses, which have high fatality rates and pandemic potential. Cell tropism ... -
Predictive Biomarkers of Intensive Care Unit and Mechanical Ventilation Duration in Critically-Ill Coronavirus Disease 2019 Patients.
( Frontiers Media , 2021 , Article)Detection of early metabolic changes in critically-ill coronavirus disease 2019 (COVID-19) patients under invasive mechanical ventilation (IMV) at the intensive care unit (ICU) could predict recovery patterns and help in ... -
Preface
( Springer International Publishing , 2019 , Other)Since its foundation in 2018, Emergent Materials aimed to focus on evolving techniques/technologies for advanced materials in a wide variety of fields such as polymer science, composites, electronics, membranes, and ... -
A preliminary study on microbial air contamination in select schools in Doha, Qatar
( Springer Nature , 2021 , Article)Available data of the indoor airborne culturable bacteria and fungi at schools’ environments is very limited in the peninsula of Qatar. This study aims to determine the microbial load in indoor and outdoor air at three ... -
Preparation, characterization, and in ovo vaccination of dextran-spermine nanoparticle DNA vaccine coexpressing the fusion and hemagglutinin genes against Newcastle disease
( Dove Press , 2016 , Article)Plasmid DNA (pDNA)-based vaccines have emerged as effective subunit vaccines against viral and bacterial pathogens. In this study, a DNA vaccine, namely plasmid internal ribosome entry site-HN/F, was applied in ovo against ... -
Prevalence and genetic diversity of Blastocystis sp. among autochthonous and immigrant patients in Italy
( Elsevier , 2023 , Article)The prevalence of Blastocystis sp., its genetic diversity and the distribution of circulating subtypes (STs) were molecularly investigated in a cohort of autochthonous and immigrant patients with gastrointestinal symptoms ... -
Prevalence and molecular profiling of Epstein Barr virus (EBV) among healthy blood donors from different nationalities in Qatar.
( Public Library of Science , 2017 , Article)The Epstein-Barr virus (EBV) is the causative agent of infectious mononucleosis. EBV is highly prevalent lymphotropic herpesvirus and has been linked to several malignancies. Transmission is generally by oral secretions, ... -
Prevalence and Phylogenetic Analysis of Parvovirus (B19V) among Blood Donors with Different Nationalities Residing in Qatar
( MDPI , 2021 , Article)Human parvovirus (B19V) is the causative agent of erythema infectiosum in children and is linked to a wide range of clinical manifestations. Studies related to B19V prevalence in the Middle East and North Africa (MENA) ...