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GATA-3 as a potential therapeutic target for insulin resistance and type 2 diabetes mellitus.
(
PubMed Central
, 2020 , Article Review)
Impaired adipogenesis plays an important role in the development of obesity-associated insulin resistance and type 2 diabetes as it leads to ectopic fat deposition. The anti-adipogenic transcription factor GATA-3 was ...
Advancing Frontiers in Bone Bioprinting
(
Wiley-VCH Verlag
, 2019 , Article Review)
Three-dimensional (3D) bioprinting of cell-laden biomaterials is used to fabricate constructs that can mimic the structure of native tissues. The main techniques used for 3D bioprinting include microextrusion, inkjet, and ...
Targeting triple negative breast cancer heterogeneity with chalcones: a molecular insight.
(
Informa Healthcare
, 2019 , Article Review)
Triple negative breast cancers (TNBCs) are aggressive heterogeneous cancers with not yet determined conventional targeted medication. Therefore, identification of new alternatives or improved treatment options to combat ...
Architecture of Viral RNA Helicases; HCV Helicase as Antiviral Target
(2018 , Article Review)
Around 80% of known viruses comprise of RNA and its specific RNA helicases that are vital for most RNA metabolism
includingpre-mRNA splicing, translation,initiation, and ribosome biogenesis. The viral helicases are crucial ...
Advances in osteobiologic materials for bone substitutes.
(
John Wiley and Sons
, 2018 , Article Review)
A significant challenge in the current orthopedics is the development of suitable osteobiologic materials that can replace the conventional allografts, autografts, and xenografts and thereby serve as implant materials as ...
Translating advances in organ-on-a-chip technology for supporting organs
(
John Wiley and Sons Inc.
, 2019 , Article Review)
Organ‐on‐a‐chip platforms have recently seen tremendous progress. They have found potential applications in the study of physiology and pathology of tissues, drug toxicity, and development of tissue models for replacement ...
The Dual Specificity Role of Transcription Factor FOXO in Type 2-diabetes and Cancer
(
Bentham Science Publishers
, 2018 , Article Review)
The FOXO (Forkhead box O) transcription factors are implicated in several signaling pathways and play a vital role in various cellular and physiological processes include for instance, ROS (reactive oxygen species) response, ...
Expression profile of MicroRNA: An Emerging Hallmark of Cancer.
(
Bentham Science Publishers
, 2019 , Article Review)
MicroRNA (miRNAs), a class of small, endogenous non-coding RNA molecules of about 21-24 nucleotides in length, have unraveled a new modulatory network of RNAs that form an additional level of post-transcriptional gene ...
Herbal medicine as an auspicious therapeutic approach for the eradication of Helicobacter pylori infection: A concise review.
(
Wiley
, 2019 , Article Review)
Helicobacter pylori (H. pylori) causes gastric mucosa inflammation and gastric cancer mostly via several virulence factors. Induction of proinflammatory pathways plays a crucial role in chronic inflammation, gastric ...
Chromosome aberrations and fertility disorders in domestic animals
(
Annual Reviews Inc.
, 2016 , Article Review)
The association between chromosomal abnormalities and reduced fertility in domestic animals is well recorded and has been studied for decades. Chromosome aberrations directly affect meiosis, gametogenesis, and the viability ...