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E-cadherin/catenin complex modulations in human oral cancer
(
Springer Netherlands
, 2015 , Book chapter)
Oral cancer is a common neoplasm in both male and female worldwide; the incidence and mortality of this cancer have increased over the past decades. Cancer metastasis is a major cause of morbidity and mortality in oral ...
E5 and E6/E7 of high-risk HPVs cooperate to enhance cancer progression through EMT initiation
(
Taylor & Francis
, 2015 , Article)
It is estimated that 10–20% of human carcinogenesis is linked to virus infection including papillomaviruses (HPVs). Moreover, since metastatic cancer disease is a major cause of morbidity and mortality in cancer patients, ...
GOLD NANOPARTICLES-BASED ASSAYS FOR DIRECT AND COST EFFECTIVE DETECTION OF CLOSTRIDIUM DIFFICILE IN QATAR
(2015 , Master Thesis)
Background
Clostridium difficile Infection (CDI) is one of the common health problems worldwide. Prevention techniques require fast and precise detection with high sensitivity. Conventional diagnostic methods are ...
Cytotoxicity and physicochemical characterization of iron–manganese-doped sulfated zirconia nanoparticles
(
Dove Press
, 2015 , Article)
Iron–manganese-doped sulfated zirconia nanoparticles with both Lewis and Brønsted acidic sites were prepared by a hydrothermal impregnation method followed by calcination at 650°C for 5 hours, and their cytotoxicity ...
Qatar Biobank and Qatar Genome Programs Road Map
(
OMICS International
, 2015 , Article)
Qatar Biobank “QBB” is a large-scale, long term medical research initiative for the population of Qatar, which will serve as a platform and driver of biomedical research to achieve benefits for Qatar’s communities. Following ...
Human olfactory bulb neural stem cells mitigate movement disorders in a rat model of Parkinson's disease.
(
Wiley
, 2015 , Article)
Parkinson's disease (PD) is a neurological disorder characterized by the loss of midbrain dopaminergic (DA) neurons. Neural stem cells (NSCs) are multipotent stem cells that are capable of differentiating into different ...
Pre-fusion structure of a human coronavirus spike protein
(
Nature Publishing Group
, 2015 , Article)
HKU1 is a human betacoronavirus that causes mild yet prevalent
respiratory disease1, and is related to the zoonotic SARS2 and
MERS3 betacoronaviruses, which have high fatality rates and
pandemic potential. Cell tropism ...
Pseudomonas aeruginosa: arsenal of resistance mechanisms, decades of changing resistance profiles, and future antimicrobial therapies.
(
Future Medicine
, 2015 , Article)
Antimicrobial resistance is one of the most serious public health issues facing humans since the discovery of antimicrobial agents. The frequent, prolonged, and uncontrolled use of antimicrobial agents are major factors ...
The Qatar Biobank: background and methods
(
BioMed Central
, 2015 , Article)
Background: The Qatar Biobank aims to collect extensive lifestyle, clinical, and biological information from up to
60,000 men and women Qatari nationals and long-term residents (individuals living in the country for ≥15 ...
Early Diagnosis of Iron Deficiency in School Children: A Qatari Experience
(
OMICS Publishing Group
, 2015 , Article)
Objective: Iron deficiency still remains the most common nutritional deficiency throughout the world and is the
leading cause of anaemia in children. Early recognition of iron deficiency, even before the development of ...