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Zebrafish larvae as a model to demonstrate secondary iron overload.
(
Wiley
, 2018 , Article)
Thalassemia is the most common genetically inherited blood disorder arising from a defect in hemoglobin production, resulting in ineffective erythropoiesis and severe hemolytic anemia. While transfusion therapy corrects ...
The association and LINKGAGE of various retroviruses ANDITS progression towards Neurodegeneration
(2018 , Article)
ABSTRACT
Effective prevention and treatment of infectious diseases has played an enormous role for the healthy outlook of human
being. However at the same time, chronic ailments such as neurodegenerative diseases are on ...
Using Zebrafish for Investigating the Molecular Mechanisms of Drug-Induced Cardiotoxicity
(
Hindawi Publishing Corporation
, 2018 , Article)
Over the last decade, the zebrafish (Danio rerio) has emerged as amodel organismfor cardiovascular research.Zebrafish have several advantages over mammalian models. For instance, the experimental cost of using zebrafish ...
Water-pipe smoking promotes epithelial-mesenchymal transition and invasion of human breast cancer cells via ERK1/ERK2 pathways.
(
BioMed Central Ltd.
, 2018 , Article)
With the increasing popularity of water-pipe smoking (WPS), it is critical to comprehend how WPS may affect women's health. The main goal of this study is to identify the potential outcome of WPS on human breast cancer ...
Hypertrophic cardiomyopathy-linked variants of cardiac myosin-binding protein C3 display altered molecular properties and actin interaction
(
Portland Press Ltd
, 2018 , Article)
The most common inherited cardiac disorder, hypertrophic cardiomyopathy (HCM), is characterized by thickening of heart muscle, for which genetic mutations in cardiac myosin-binding protein C3 (c-MYBPC3) gene, is the leading ...
Use of Hemagglutinin Stem Probes Demonstrate Prevalence of Broadly Reactive Group 1 Influenza Antibodies in Human Sera.
(
Nature Publishing Group
, 2018 , Article)
A better understanding of the seroprevalence and specificity of influenza HA stem-directed broadly neutralizing antibodies (bNAbs) in the human population could significantly inform influenza vaccine design efforts. Here, ...
Fabrication and In Vitro Characterization of a Tissue Engineered PCL-PLLA Heart Valve.
(
Nature Publishing Group
, 2018 , Article)
Heart valve diseases are among the leading causes of cardiac failure around the globe. Nearly 90,000 heart valve replacements occur in the USA annually. Currently, available options for heart valve replacement include ...
Computational screening of known broad-spectrum antiviral small organic molecules for potential influenza HA stem inhibitors.
(
Public Library of Science
, 2018 , Article)
With the emergence of new influenza virus strains that are resistant to current inhibitors such as oseltamivir (anti-neuraminidase (NA)) and amantadine (anti-M2 proton channel), influenza A viruses continue to be a serious ...
Toxicity evaluation of selected ionic liquid compounds on embryonic development of Zebrafish.
(
Elsevier
, 2018 , Article)
Hydrate formation in seafloor pipelines is considered an economic and flow assurance issue for the oil and gas industries. Ionic liquids (ILs) have been recently used as potential hydrate inhibitors. Although branded as ...
Seroprevalence of herpes simplex virus types 1 and 2 in Indian and Filipino migrant populations in Qatar: a cross-sectional survey
(
World Health Organization
, 2018 , Article)
Background: The epidemiology of herpes simplex virus infections is of growing interest but
information on its seroprevalence in many countries is scarce.
Aims: This study aimed to measure the seroprevalence of herpes ...