Biomedical Research Center Research: Recent submissions
Now showing items 481-500 of 738
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Metabolic profiling of pre-gestational and gestational diabetes mellitus identifies novel predictors of pre-term delivery.
( BMC , 2020 , Article)Pregnant women with gestational diabetes mellitus (GDM) or type 2 diabetes mellitus (T2DM) are at increased risks of pre-term labor, hypertension and preeclampsia. In this study, metabolic profiling of blood samples collected ... -
Water-Pipe Smoking Exposure Deregulates a Set of Genes Associated with Human Head and Neck Cancer Development and Prognosis.
( MDPI , 2020 , Article)Water-pipe smoking (WPS) is becoming the most popular form of tobacco use among the youth, especially in the Middle East, replacing cigarettes rapidly and becoming a major risk of tobacco addiction worldwide. Smoke from ... -
Co-incidence of Human Papillomaviruses and Epstein-Barr Virus Is Associated With High to Intermediate Tumor Grade in Human Head and Neck Cancer in Syria.
( Frontiers Media , 2020 , Article)High-risk human papillomaviruses (high-risk HPVs) have been recently reported to be co-present with Epstein-Barr virus (EBV) in different types of human cancers including head and neck (HN), where they can cooperate in the ... -
Elaeagnus angustifolia Plant Extract Inhibits Epithelial-Mesenchymal Transition and Induces Apoptosis via HER2 Inactivation and JNK Pathway in HER2-Positive Breast Cancer Cells
( MDPI , 2020 , Article)Elaeagnus angustifolia (EA) is a medicinal plant used for treating several human diseases in the Middle East. Meanwhile, the outcome of extract on HER2-positive breast cancer remains nascent. Thus, we herein investigated ... -
Design of hybrid clay/ polypyrrole decorated with silver and zinc oxide nanoparticles for anticorrosive and antibacterial applications
( Elsevier , 2020 , Article)In this work, a novel and cost-effective bentonite intercalated with polypyrrole Zinc oxide-silver nanocomposite (B-PPy/ZnO) hybrid material was prepared via in situ photopolymerization of pyrrole in the presence of silanized ... -
Inter-Versus Intra-Host Sequence Diversity of pH1N1 and Associated Clinical Outcomes
( MDPI , 2020 , Article)The diversity of RNA viruses dictates their evolution in a particular host, community or environment. Here, we reported within- and between-host pH1N1virus diversity at consensus and sub-consensus levels over a three-year ... -
Identification of mcr-8 in Clinical Isolates From Qatar and Evaluation of Their Antimicrobial Profiles
( Frontiers Media , 2020 , Article)This study was performed to investigate the genotypic causes of colistin resistance in 18 colistin-resistant Klebsiella pneumoniae (n = 13), Escherichia coli (n = 3) and Pseudomonas aeruginosa (n = 2) isolates from patients ... -
Covid-19: Challenges & Perspectives
( College of Medicine - Qatar University , 2020 , Conference Paper)A Virtual Conference to shed light on the QU's prominent trends and research efforts addressing Corona virus. -
Materials Against COVID-19: How Materials Science can Impact the Pandemic?
( Emergent Materials Journal - Qatar University , 2020 , Video)This webinar aims to gather scientists, clinicians, and industry experts working on coronavirus (COVID-19). The focus of the event is a variety of material science applications for detection, prevention, and treatment of ... -
Glycan repositioning of influenza hemagglutinin stem facilitates the elicitation of protective cross-group antibody responses.
( Nature Research , 2020 , Article)The conserved hemagglutinin (HA) stem has been a focus of universal influenza vaccine efforts. Influenza A group 1 HA stem-nanoparticles have been demonstrated to confer heterosubtypic protection in animals; however, the ... -
Detection of SARS-CoV-2 RNA by direct RT-qPCR on nasopharyngeal specimens without extraction of viral RNA.
( Public Library of Science , 2020 , Article)To circumvent the limited availability of RNA extraction reagents, we aimed to develop a protocol for direct RT-qPCR to detect SARS-CoV-2 in nasopharyngeal swabs without RNA extraction. Nasopharyngeal specimens positive ... -
Combined chemo-magnetic field-photothermal breast cancer therapy based on porous magnetite nanospheres
( Nature Research , 2020 , Article)The efficacy of different modalities of treating breast cancer is inhibited by several limitations such as off-targeted drug distribution, rapid drug clearance, and drug resistance. To overcome these limitations, we developed ... -
Loop-mediated isothermal amplification (Lamp): A rapid, sensitive, specific, and cost-effective point-of-care test for coronaviruses in the context of covid-19 pandemic
( MDPI , 2020 , Article)The rampant spread of COVID-19 and the worldwide prevalence of infected cases demand a rapid, simple, and cost-effective Point of Care Test (PoCT) for the accurate diagnosis of this pandemic. The most common molecular tests ... -
Poly(lactic-co-glycolic acid) Nanoparticles Loaded with Callistemon citrinus Phenolics Exhibited Anticancer Properties against Three Breast Cancer Cell Lines
( Hindawi Limited , 2019 , Article)Fruit and vegetable diets rich in phenolic compounds reduce the risk of various cancers and offer multiple other health benefits due to their bioactivity and powerful antioxidant properties. However, the human health ... -
Hyperhydration-induced decrease in urinary luteinizing hormone concentrations of Male athletes in doping control analysis
( Human Kinetics Publishers Inc. , 2019 , Article)Low urinary luteinizing hormone (LH) values have been discussed as a marker to detect steroid abuse. However, suppressed LH concentrations related to highly diluted urine samples could be a misleading indication of anabolic ... -
Fabrication and evaluation of anti-cancer efficacy of lactoferrin-coated maghemite and magnetite nanoparticles
( Taylor and Francis Ltd. , 2019 , Article)Studies on the anti-cancer effects of nanomaterials are a very important step in the clinical practice and treatment of cancerous tissues. Since IONPs have a high potential for cancer treatment, their anti-cancer properties ... -
Experimental investigation of volume fraction in an annulus using electrical resistance tomography
( Society of Petroleum Engineers , 2019 , Conference Paper)Horizontal drilling technology has shown to improve the production and cost-effectiveness of the well by generating multiple extraction points from a single vertical well. The efficiency of hole cleaning is reduced because ... -
Phenolic contents-based assessment of therapeutic potential of Syzygium cumini leaves extract
( Public Library of Science , 2019 , Article)Syzygium cumini (S. cumini) is an evergreen tropical plant that is well recognized for its therapeutic potential of common diseases. In this study, the therapeutic potential and biomedical application of S. cumini are ... -
Suppression of GATA-3 increases adipogenesis, reduces inflammation and improves insulin sensitivity in 3T3L-1 preadipocytes
( Elsevier , 2020 , Article)© 2020 Impaired adipogenesis plays an important role in the development of obesity-associated insulin resistance and type 2 diabetes. Adipose tissue inflammation is a crucial mediator of this process. GATA-3 plays important ... -
Prevalence of antibiotic resistant Escherichia coli isolates from local and imported retail chicken carcasses.
( International Association for Food Protection , 2020 , Article)The spread of antibiotic resistance has been associated with consumption of food contaminated with pathogenic and non-pathogenic resistant bacteria. The objective of this study was to determine the prevalence of antibiotic ...
