Show simple item record

AuthorAhmed, Mustafa
AuthorMaliyakkal, Abdul Majeed
Available date2023-08-05T11:56:21Z
Publication Date2022-05-01
Publication NameCureus‏
Identifierhttp://dx.doi.org/10.7759/cureus.25061
CitationAhmed, M., & Maliyakkal, A. M. (2022). Non-ST-Segment Elevation Myocardial Infarction Shortly After Starting Steroid Replacement Therapy in a Patient With Adrenal Insufficiency. Cureus, 14(5).‏
URIhttp://hdl.handle.net/10576/46472
AbstractAdrenal insufficiency is a rare disorder that results from etiological factors affecting either the hypothalamic-pituitary axis or the adrenal gland itself. Studies have associated an inherently increased risk of cardiovascular events with this condition. It is treated with exogenous steroid supplementation. However, in recent years, there have been an increasing number of reports regarding the potential of steroid therapy to precipitate acute cardiac events. However, this risk is generally assumed to be dose-dependent and could be absent in patients receiving low-dose glucocorticoid treatment. We present a case of a 71-year-old woman who was admitted to our institution with bilateral lower limb swelling. Blood investigation revealed hypoalbuminemia and hyponatremia. Upon further evaluation she was diagnosed to have adrenal insufficiency and was started on hydrocortisone replacement therapy; however, the patient developed non-ST-segment elevation myocardial infarction (NSTEMI) and acute pulmonary edema a few days after starting steroid replacement therapy. Here, we discuss the possible association between hydrocortisone use and the development of acute cardiac events.
Languageen
Subjectadrenal insufficiency
cardiovascular risk
glucocorticoid replacement
hydrocortisone
st-elevation myocardial infarction (stemi)
TitleNon-ST-Segment Elevation Myocardial Infarction Shortly After Starting Steroid Replacement Therapy in a Patient With Adrenal Insufficiency.
TypeArticle


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record