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Bladder neoplasms and NF-κB: an unfathomed association.
(
Taylor & Francis
, 2020 , Article)
Bladder cancer is the second most common genitourinary tract cancer and is often recurrent and/or chemoresistant after tumor resection. Cigarette smoking, exposure to aromatic amines, and chronic infection/inflammation are ...
Molecular dynamics simulations to decipher the structural and functional consequences of pathogenic missense mutations in the galactosylceramidase (GALC) protein causing Krabbe's disease.
(
Taylor & Francis
, 2020 , Article)
Krabbe disease (KD), also known as globoid cell leukodystrophy disease, is an autosomal recessive lysosomal storage genetic disorder, which is caused by the deficiecncy of galactocerebrosidase (GALC) coding gene (). This ...
Characteristics of cardiac rehabilitation programs in Latin America and the Caribbean, and estimation of capacity and needs in the region
(
European Society of Cardiology
, 2020 , Conference Paper)
Background
Cardiac rehabilitation (CR) is an established model of cardiovascular (CV) prevention that has proven benefits. Availability, characteristics and need of CR programs in Latin-American and Caribbean (LAC) countries ...
Development of the international cardiac rehabilitation registry data dictionary using a Delphi process
(2020 , Conference Paper)
Background: Cardiac rehabilitation (CR) registries are a powerful tool for improvement
of care quality, and consequently patients’ outcomes. However, there are few CR registries
worldwide, with Canada’s currently being ...
Metformin is comparable to insulin for pharmacotherapy in gestational diabetes mellitus: A network meta-analysis evaluating 6046 women.
(
Elsevier
, 2021 , Article)
The comparative efficacy of gestational diabetes (GDM) treatments lack conclusive evidence for choice of first-line treatment. The aim of this study was to compare the efficacy of metformin and glibenclamide to insulin ...
Computational model to analyze and characterize the functional mutations of NOD2 protein causing inflammatory disorder - Blau syndrome.
(
Elsevier
, 2020 , Article)
Blau syndrome (BS), which affects the eyes, skin, and joints, is an autosomal dominant genetic inflammatory disorder. BS is caused by mutations in the NOD2 gene. However, there are no direct treatments, and treatment with ...
Frailty predicts adverse outcomes in older patients undergoing transcatheter aortic valve replacement (TAVR). From the National Inpatient Sample
(
Elsevier
, 2021 , Article)
ObjectiveWe aimed to study the impact of frailty on the outcome of transcatheter aortic valve replacement (TAVR) procedures. MethodsThe National Inpatient Sample (NIS) database was queried for all patients aged ≥65 years ...
Perceived risk, behavior changes and Health-related outcomes during COVID-19 pandemic: Findings among adults with and without diabetes in China
(
Elsevier Ireland Ltd
, 2020 , Article)
Aims: To examine perceived infection risk of COVID-19 and the health and related behavior changes among people with diabetes, compared with people without diabetes, and to examine factors associated with self-reported ...
The polymorphism at the microRNA-155 binding site in AGTR1 gene is not significantly associated with rheumatic heart disease in Saudi Arabia population
(
Bentham Science Publishers
, 2020 , Article)
Rheumatic heart disease (RHD) remains a major cause of cardiovascular diseases and the most devastating effects are on children and young adults. RHD is caused due to the interaction between microbial, environmental, ...
Barriers and Motivators of Appropriate Antibiotic Prescription at PHCC in Qatar: Perspective of Physicians and Pharmacists
(
Ministry of Public Health
, 2020 , Conference Paper)
Antimicrobial resistance (AMR) is a serious public health problem of global concern. The Ministry of Public Health (MOPH) developed the NAP (National Action Plan) to combat AMR in Qatar in collaboration with WHO/EMRO. ...