Biomedical Sciences: Recent submissions
Now showing items 1-20 of 595
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Association between metabolically healthy obesity and metastasis in lung cancer patients – a systematic review and meta-analysis
( Frontiers Media , 2023 , Article Review)Background: Many clinical trials have looked at the relationship between obesity and lung cancer (LC), however, there is scarcity of literature specifically addressing the association between metabolically healthy obesity ... -
Enhancing Cardiovascular Health and Functional Recovery in Stroke Survivors: A Randomized Controlled Trial of Stroke-Specific and Cardiac Rehabilitation Protocols for Optimized Rehabilitation
( MDPI , 2023 , Article)Background: Stroke is a major contributor to disability and mortality globally. It leads to physical impairments, including weakness and cardiovascular deconditioning, posing significant challenges to stroke survivors’ ... -
The Qatari population's genetic structure and gene flow as revealed by the Y chromosome
( Public Library of Science , 2023 , Article)The Y-chromosome has been widely used in forensic genetic applications and human population genetic studies due to its uniparental origins. A large database on the Qatari population was created for comparison with other ... -
Airway and Oral microbiome profiling of SARS-CoV-2 infected asthma and non-asthma cases revealing alterations-A pulmonary microbial investigation
( NLM (Medline) , 2023 , Article)New evidence strongly discloses the pathogenesis of host-associated microbiomes in respiratory diseases. The microbiome dysbiosis modulates the lung's behavior and deteriorates the respiratory system's effective functioning. ... -
Metabolomics Approaches for the Diagnosis, Treatment, and Better Disease Management of Viral Infections
( MDPI , 2023 , Article Review)Metabolomics is an analytical approach that involves profiling and comparing the metabolites present in biological samples. This scoping review article offers an overview of current metabolomics approaches and their ... -
Combined experimental and computational investigations of the fluorosolvatochromism of chromeno[4,3-b]pyridine derivatives: Effect of the methoxy substitution
( Elsevier , 2023 , Article)Extensive research has been conducted on the spectral properties of chromeno[4,3-b]pyridine derivatives, owing to their potential applications in sensing, optoelectronic devices, and drug discovery. This study presents a ... -
Adult appendicitis score versus Alvarado score: A comparative study in the diagnosis of acute appendicitis
( Elsevier , 2023 , Article)Background Acute Appendicitis (AA) is the most common abdominal surgical emergency. It requires proper management to decrease mortality and morbidity. Clinical scoring systems for diagnosing AA aimed to decrease the use ... -
Helicobacter pylori and epithelial mesenchymal transition in human gastric cancers: An update of the literature
( Elsevier , 2023 , Article Review)Gastric cancer, a multifactorial disease, is considered one of the most common malignancies worldwide. In addition to genetic and environmental risk factors, infectious agents, such as Epstein-Barr virus (EBV) and Helicobacter ... -
Biological Performance of Primary Dental Pulp Stem Cells Treated with Gold Nanoparticles
( MDPI , 2023 , Article)Gold nanoparticles (AuNPs) are one of the most stable nanoparticles that have been prevalently used as examples for biological and biomedical applications. Herein, we evaluate the effect of AuNPs on the biological processes ... -
Association of Vitamin D Genetic Risk Score with Noncommunicable Diseases: A Systematic Review
( MDPI , 2023 , Article)Background and Aims: The genetic risk score (GRS) is an important tool for estimating the total genetic contribution or susceptibility to a certain outcome of interest in an individual, taking into account their genetic ... -
Turning point in COVID-19 severity and fatality during the pandemic: a national cohort study in Qatar
( BMJ Publishing Group , 2023 , Article)Objective To assess the evolution of COVID-19 severity and fatality in a unique setting that consistently applied, throughout the pandemic, rigorous and standardised criteria for defining severe COVID-19 outcomes. Methods ... -
Seroprevalence of hepatitis E virus (HEV) among male craft and manual workers in Qatar (2020–2021)
( Elsevier , 2023 , Article)BackgroundThe rapid growth of Qatar in the last two decades has attracted a large influx of immigrant craft and manual workers (CMWs) seeking employment in jobs associated with food handling, domestic service, and construction. ... -
History of primary-series and booster vaccination and protection against Omicron reinfection
( American Association for the Advancement of Science , 2023 , Article)Laboratory evidence suggests a possibility of immune imprinting for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We investigated the differences in the incidence of SARS-CoV-2 reinfection in a ... -
Short- and longer-term all-cause mortality among SARS-CoV-2- infected individuals and the pull-forward phenomenon in Qatar: a national cohort study
( Elsevier , 2023 , Article)ObjectivesWe assessed short-, medium-, and long-term all-cause mortality risks after a primary SARS-CoV-2 infection. MethodsA national, matched, retrospective cohort study was conducted in Qatar to assess risk of all-cause ... -
A new horizon in the phosphorylated sites of AGA: the structural impact of C163S mutation in aspartylglucosaminuria through molecular dynamics simulation
( Taylor and Francis Ltd. , 2023 , Article)Aspartylglucosaminuria (AGU) is a lysosomal storage disorder caused by insufficient aspartylglucosaminidase (AGA) activity leading to chronic neurodegeneration. We utilized the PhosphoSitePlus tool to identify the AGA ... -
Sex distinctive patterns in the association between serum bicarbonate and uric acid levels among healthy adults. Qatar biobank data
( Frontiers Media S.A. , 2023 , Article)Background: Uric acid is the final product of purine metabolism and is a potent plasma antioxidant but with pro-inflammatory effects. At high levels, it may increase the risk of developing multiple chronic diseases, such ... -
Student perspectives on the integration of artificial intelligence into healthcare services
( SAGE Publications Inc. , 2023 , Article)Background: Healthcare workers are often overworked, underfunded, and face many challenges. Integration of artificial intelligence into healthcare service provision can tackle these challenges by relieving burdens on ... -
Testosterone treatment and change of categories of the International prostate symptom score (IPSS) in hypogonadal patients: 12 years prospective controlled registry study
( Taylor and Francis Ltd. , 2023 , Article)Functional hypogonadism is a condition characterized by low testosterone concentrations, occurring more commonly in men as they age. The International Prostate Symptom Score (IPSS) is used to categorize the severity of ... -
Testing the Anticancer Effect of Matcha Using Zebrafish as an Animal Model
( MDPI , 2023 , Article)Cancer is the second leading cause of death worldwide, and triple-negative breast cancer (TNBC) patients show the poorest prognosis and survival and the highest metastasis prevalence among all breast cancer subtypes. Matcha ... -
The Impact of ACE Gene Variants on Acute-Phase Reactants in Children with Rheumatic Heart Disease
( MDPI , 2023 , Article)Rheumatic heart disease (RHD) is the most important sequela of upper respiratory group A Streptococcus (GAS) infection. The role of the common angiotensin-converting enzyme (ACE) insertion/deletion (I/D) variant in the ...