Biomedical Sciences: المرسلات الحديثة
السجلات المعروضة 1 -- 20 من 844
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Molecular insights and emerging therapeutic perspectives of the lncRNA GAS5/miR-21 axis in cancer, fibrosis, cardiovascular, and immune disorders
( Elsevier , 2025 , Article)Non-coding RNAs (ncRNAs) have redefined the complexity of gene regulation, with the long non-coding (lncRNA) GAS5/miR-21 axis emerging as a critical determinant of cell fate across diverse pathological contexts. This review ... -
Global burden of chikungunya virus infections and the potential benefit of vaccination campaigns
( Nature Research , 2025 , Article)The first vaccine against chikungunya virus (CHIKV) has now been licensed; however, due to a limited knowledge of the underlying global burden, its potential to reduce disease burden remains unknown. We used data from ... -
Immune histories and natural infection protection during the omicron era
( Springer Nature , 2025 , Article)Background: Past immunological events can either enhance or compromise an individual's future immune protection. This study investigated how different severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) natural ... -
JAK-STAT Signaling in Autoimmunity and Cancer
( Dove Medical Press Ltd , 2025 , Article Review)The JAK-STAT pathway is an essential cell survival signaling that regulates gene expressions related to inflammation, immunity and cancer. Cytokine receptors, signal transducer and activator of transcription (STAT) proteins, ... -
Insects in agricultural greenhouses: a metagenomic analysis of microbes in Trialeurodes vaporariorum infesting tomato and cucumber crops
( Frontiers Media SA , 2025 , Article)Introduction: With the predicted 9-10 billion world population increase by 2050 and its accompanying need for sustainable food production, and with the harsh climate conditions challenging agriculture and food security in ... -
Machine learning applications in the analysis of sedentary behavior and associated health risks
( Frontiers Media SA , 2025 , Article Review)Background: The rapid advancement of technology has brought numerous benefits to public health but has also contributed to a rise in sedentary lifestyles, linked to various health issues. As prolonged inactivity becomes a ... -
Development of an RT-LAMP Assay for Detecting tet(M) in Enterococcus Species: Enhancing AMR Surveillance Within the One Health Sectors
( Multidisciplinary Digital Publishing Institute (MDPI) , 2025 , Article)The increasing prevalence of antimicrobial-resistant (AMR) bacteria in humans, animals, and the environment underscores the necessity for a rapid, sensitive, and specific method to identify resistance genes. Objectives: ... -
Silicone quaterium-22 surfactant as an eco-friendly carbon steel anticorrosive: Assessment of corrosion inhibition properties and ecotoxicity in zebrafish embryos
( Elsevier , 2025 , Article)Corrosion of carbon steel pipelines in the oil and gas industry presents operational and environmental challenges, requiring safer alternatives to toxic corrosion inhibitors. This study evaluates Silicon-Q-22 (SQ22) as a ... -
Comprehensive global-scale evaluation of the COVID-19 pandemic associated with 234 countries, territories, and sub-national locations during 2020–2024
( Springer Nature , 2025 , Article)Comprehensive estimation of COVID-19, including infection, death, excess mortality, case fatality rate (CFR), and infection fatality rate (IFR), is essential for understanding the pandemic’s pattern. The location-specific ... -
Correction to: Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels (Emergent Materials, (2025), 8, 2, (985-998), 10.1007/s42247-024-00888-7)
( Springer Nature , 2025 , Article)The original version of this publication contained wrong texts in the Acknowledgement section and in the Author contributions section. In addition, the article note on page 1 has been corrected. These errors have been ... -
Comprehensive performance evaluation of four chemiluminescence immunoassays for detecting vitamin D deficiency across diverse clinical conditions
( The Public Library of Science (PLOS) , 2025 , Article)Background/Objectives Vitamin D deficiency is a significant global health concern, requiring accurate diagnosis. This study evaluates the performance of four chemiluminescent immunoassay (CLIA) platforms; Snibe, Roche, ... -
Silver-based dressings for the prevention of surgical site infections: evidence from randomized trials
( Elsevier , 2025 , Article)BackgroundSurgical site infections (SSIs) are a major cause of postoperative complications, increasing morbidity and healthcare costs. Silver-based dressings are commonly used due to their antimicrobial properties, but ... -
Outcomes and management of Peyronie’s disease with combined treatment of collagenase clostridium histolyticum, vacuum erection device, and tadalafil
( Wolters Kluwer Medknow Publications , 2025 , Article)Peyronie’s disease (PD) is a connective tissue disorder characterized by abnormal collagen deposition in the tunica albuginea, leading to penile curvature, pain, and erectile dysfunction. This study aimed to evaluate the ... -
Exploring Differentially Methylated Genes among Preterm Birth and Full-Term Birth
( Karger , 2025 , Article)INTRODUCTION: Preterm birth (PTB) is a major contributor to neonatal morbidity and mortality. DNA methylation plays a critical role in fetal development and may serve as an epigenetic biomarker for PTB. However, few ... -
Characterizing low femoral neck BMD in Qatar Biobank participants using machine learning models
( Springer Nature , 2025 , Article)Background: Identifying determinants of low bone mineral density (BMD) is crucial for understanding the underlying pathobiology and developing effective prevention and management strategies. Here we applied machine learning ... -
Near-complete Middle Eastern genomes refine autozygosity and enhance disease-causing and population-specific variant discovery
( Elsevier , 2025 , Article)Advances in long-read sequencing have enabled routine complete assembly of human genomes, but much remains to be done to represent broader populations and show impact on disease-gene discovery. Here, we report highly ... -
Diet-induced mechanical stress promotes immune and metabolic alterations in the Drosophila melanogaster digestive tract
( Elsevier , 2025 , Article)A fundamental query in immunology is how cells recognize danger in the tissue milieu. For many years, standpoints were mainly centered around damaged cells or structures of invading pathogens, like lipopolysaccharide, being ... -
The role of soluble CD40L in autoimmune diseases
( Elsevier , 2025 , Article)CD40−CD40L is essential for immune system modulation because it coordinates both adaptive and inflammatory responses.Systemic lupus erythematosus, multiple sclerosis, inflammatory bowel disease, thrombocytopenic purpura, ... -
Comprehensive analysis of human coronavirus antibody responses in ICU and non-ICU COVID-19 patients reveals IgG3 against SARS-CoV-2 spike protein as a key biomarker of disease severity
( Microbiology Society , 2025 , Article)Introduction. Pre-existing immunity to human coronaviruses (HCoVs) may shape the immune response in COVID-19 patients. Increasing evidence suggests that immune cross-reactivity between SARS-CoV-2 and other coronaviruses ... -
Antibody-dependent enhancement of SARS-CoV-2, the impact of variants and vaccination
( Taylor and Francis Group , 2025 , Article)This study characterized antibody-dependent enhancement (ADE) in serum samples from individuals exposed to SARS-CoV-2 via infection or vaccination and evaluated its association with SARS-CoV-2 variants (Wuhan and Omicron), ...
