Browsing Biomedical Sciences by Author "Alsamman, Alsamman M."
Now showing items 1-7 of 7
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Bioinformatics investigation on blood-based gene expressions of Alzheimer's disease revealed ORAI2 gene biomarker susceptibility: An explainable artificial intelligence-based approach
Sekaran, Karthik; Alsamman, Alsamman M.; George Priya Doss, C.; Zayed, Hatem ( Springer , 2023 , Article)The progressive, chronic nature of Alzheimer's disease (AD), a form of dementia, defaces the adulthood of elderly individuals. The pathogenesis of the condition is primarily unascertained, turning the treatment efficacy ... -
Evolving strategies and application of proteins and peptide therapeutics in cancer treatment
Mukherjee, Anirban Goutam; Wanjari, Uddesh Ramesh; Gopalakrishnan, Abilash Valsala; Bradu, Pragya; Biswas, Antara; Ganesan, Raja; Renu, Kaviyarasi; Dey, Abhijit; Vellingiri, Balachandar; El Allali, Achraf; Alsamman, Alsamman M.; Zayed, Hatem; George Priya Doss, C.... more authors ... less authors ( Elsevier , 2023 , Article Review)Several proteins and peptides have therapeutic potential and can be used for cancer therapy. By binding to cell surface receptors and other indicators uniquely linked with or overexpressed on tumors compared to healthy ... -
The Implication of Mechanistic Approaches and the Role of the Microbiome in Polycystic Ovary Syndrome (PCOS): A Review
Mukherjee, Anirban Goutam; Wanjari, Uddesh Ramesh; Kannampuzha, Sandra; Murali, Reshma; Namachivayam, Arunraj; Ganesan, Raja; Dey, Abhijit; Babu, Achsha; Renu, Kaviyarasi; Vellingiri, Balachandar; Ramanathan, Gnanasambandan; George Priya Doss, C.; Elsherbiny, Nehal; Elsherbini, Amira M.; Alsamman, Alsamman M.; Zayed, Hatem; Gopalakrishnan, Abilash Valsala... more authors ... less authors ( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)As a complex endocrine and metabolic condition, polycystic ovarian syndrome (PCOS) affects women’s reproductive health. These common symptoms include hirsutism, hyperandrogenism, ovulatory dysfunction, irregular menstruation, ... -
Integrated gene network analysis sheds light on understanding the progression of Osteosarcoma
Dey, Hrituraj; Vasudevan, Karthick; Doss C, George Priya; Kumar, S. Udhaya; El Allali, Achraf; Alsamman, Alsamman M.; Zayed, Hatem... more authors ... less authors ( National library of medicine , 2023 , Article)Introduction: Osteosarcoma is a rare disorder among cancer, but the most frequently occurring among sarcomas in children and adolescents. It has been reported to possess the relapsing capability as well as accompanying ... -
The transcriptomic profiling of SARS-CoV-2 compared to SARS, MERS, EBOV, and H1N1
Alsamman, Alsamman M; Zayed, Hatem ( Public Library of Science , 2020 , Article)The SARS-CoV-2 (COVID-19) pandemic is a global crisis that threatens our way of life. As of November 18, 2020, SARS-CoV-2 has claimed more than 1,342,709 lives, with a global mortality rate of ~2.4% and a recovery rate of ... -
Unraveling the Dysbiosis of Vaginal Microbiome to Understand Cervical Cancer Disease Etiology—An Explainable AI Approach
Sekaran, Karthik; Varghese, Rinku Polachirakkal; Gopikrishnan, Mohanraj; Alsamman, Alsamman M.; El Allali, Achraf; Zayed, Hatem; Doss C, George Priya... more authors ... less authors ( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)Microbial Dysbiosis is associated with the etiology and pathogenesis of diseases. The studies on the vaginal microbiome in cervical cancer are essential to discern the cause and effect of the condition. The present study ... -
Whole-Genome Sequencing of 100 Genomes Identifies a Distinctive Genetic Susceptibility Profile of Qatari Patients with Hypertension
Alsamman, Alsamman M.; Almabrazi, Hakeem; Zayed, Hatem ( MDPI , 2022 , Article)Essential hypertension (EH) is a leading risk condition for cardiovascular and renal com-plications. While multiple genes are associated with EH, little is known about its genetic etiology. Therefore, this study aimed to ...