Browsing Biomedical Sciences by Title
Now showing items 181-200 of 712
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Do preexisting antibodies against seasonal coronaviruses have a protective role against SARS-CoV-2 infections and impact on COVID-19 severity?
( Elsevier , 2022 , Other)Because of the emergence of coronavirus disease 2019 (COVID-19), caused by the novel severe acute respiratory syndrome coronavirus (SARS-CoV-2), many questions remain unresolved regarding the abundance of cross-reactivity ... -
Docosahexaenoic Acid Counteracts the Hypoxic-Induced Inflammatory and Metabolic Alterations in 3T3-L1 Adipocytes
( MDPI , 2022 , Article)Background: Hypoxia is caused by the excessive expansion of the white adipose tissue (AT) and is associated with obesity-related conditions such as insulin resistance, inflammation, and oxidative stress. Docosahexaenoic ... -
Drosophila as a Model Organism in Host–Pathogen Interaction Studies
( Frontiers Media , 2020 , Article Review)Owing to the genetic similarities and conserved pathways between a fruit fly and mammals, the use of the Drosophila model as a platform to unveil novel mechanisms of infection and disease progression has been justified and ... -
Drug repurposing in cancer: Now and beyond
(2021 , Other)No Abdtract -
Drug repurposing in neurodegenerative and cardiovascular diseases
( Bentham Science Publishers , 2021 , Other)No Abstract -
The Dual Specificity Role of Transcription Factor FOXO in Type 2-diabetes and Cancer
( Bentham Science Publishers , 2018 , Article Review)The FOXO (Forkhead box O) transcription factors are implicated in several signaling pathways and play a vital role in various cellular and physiological processes include for instance, ROS (reactive oxygen species) response, ... -
Durable immunity to oncogenic human papillomaviruses elicited by adjuvanted recombinant Adeno-associated virus-like particle immunogen displaying L2 17-36 epitopes
( Elsevier , 2015 , Article)Vaccination with the minor capsid protein L2, notably the 17–36 neutralizing epitope, induces broadly protective antibodies, although the neutralizing titers attained in serum are substantially lower than for the licensed ... -
Duration of immune protection of SARS-CoV-2 natural infection against reinfection.
( Oxford University Press , 2022 , Article)The future of the SARS-CoV-2 pandemic hinges on virus evolution and duration of immune protection of natural infection against reinfection. We investigated duration of protection afforded by natural infection, the effect ... -
Duration of mRNA vaccine protection against SARS-CoV-2 Omicron BA.1 and BA.2 subvariants in Qatar.
( Nature Research , 2022 , Article)SARS-CoV-2 Omicron BA.1 and BA.2 subvariants are genetically divergent. We conducted a matched, test-negative, case-control study to estimate duration of protection of the second and third/booster doses of mRNA COVID-19 ... -
Dysbiosis of the Salivary Microbiome is Associated with Hypertension and Correlated with Metabolic Syndrome Biomarkers
( Dovepress , 2021 , Article)Background: Hypertension (HT) is an idiopathic disease with severe complications and a high incidence of global mortality. Although the disease shares characteristic features with diabetes and obesity, the complex interplay ... -
Dysregulation of Signaling Pathways Due to Differentially Expressed Genes From the B-Cell Transcriptomes of Systemic Lupus Erythematosus Patients - A Bioinformatics Approach.
( Frontiers Media , 2020 , Article)Systemic lupus erythematosus (SLE) is an autoimmune inflammatory disorder that is clinically complex and has increased production of autoantibodies. Via emerging technologies, researchers have identified genetic variants, ... -
E-Cigarette Liquid Provokes Significant Embryotoxicity and Inhibits Angiogenesis.
( MDPI , 2020 , Article)E-cigarette smoking (ECS) is a new method of tobacco smoking that is gaining popularity as it is thought to be a "healthy method" of tobacco consumption. The adverse outcomes of ECS on the respiratory and cardiovascular ... -
Early Hepatic Gene Expression Profile of Lipid Metabolism of Mice on High Fat Diet after Treatment with Anti‐Obesity Drugs
( FASEB , 2020 , Conference Paper)Obesity is a multifactorial disorder of global scale. The liver plays a vital role in fat metabolism. Disorder of hepatic fat metabolism is associated with obesity and fatty liver disease. This study aimed to detect the ... -
Eco-friendly highly efficient BN/rGO/TiO2 nanocomposite visible-light photocatalyst for phenol mineralization
( Springer , 2021 , Article)Boron nitride (BN) and reduced graphene oxide (rGO) of different loadings were composited with commercial P25 TiO2 (Ti) through the hydrothermal method. The as-prepared nanocomposites were characterized using various ... -
Ecotoxicity and environmental safety assessment of two-dimensional niobium carbides (MXenes)
( Elsevier , 2024 , Article)Two-dimensional (2D) MXenes have gained great interest in water treatment, biomedical, and environmental applications. The antimicrobial activity and cell toxicity of several MXenes including Nb4C3Tx and Nb2CTx have already ... -
Ecotoxicological Assessment of Thermally- and Hydrogen-Reduced Graphene Oxide/TiO₂ Photocatalytic Nanocomposites Using the Zebrafish Embryo Model.
( MDPI , 2019 , Article)Advanced oxidation processes (AOPs) have recently attracted great interest in water pollution management. Using the zebrafish embryo model, we investigated the environmental impacts of two thermally (RGOTi)- and hydrogen ... -
Ecotoxicological assessment of Ti3C2Tx (MXene) using a zebrafish embryo model
( Royal Society of Chemistry , 2018 , Article)The recent application of 2D Ti3C2Tx (MXene) nanomaterials as adsorbents and membranes for water treatment as well as for biomedical applications is attracting a growing interest. However, the environmental impact of MXene ... -
Ecotoxicological assessment of two surfactant on the emryonic development
( Qatar University Press , 2021 , Poster)In this study, zebrafish (Danio rerio) embryos was served as a model for marine fauna to determine if there is any potential of organ-specific toxicity (neuromuscular, hepatic, cytotoxic, and cardiac) caused by Silicone-Q-22 ... -
Editorial: Unconventional Animal Models in Infectious Disease Research
( Frontiers Media , 2021 , Other)Beyond an in vitro setting, the use of a biological system is considered imperious to unravel the enigma of host-pathogen interactions, particularly those eventuating in an infectious disease scenery. In the past two-decades, ... -
Editorial: Unconventional Animal Models in Infectious Disease Research – Part I
( Frontiers Media , 2021 , Article)Editorial on the Research Topic Unconventional Animal Models in Infectious Disease Research