Browsing Biomedical Sciences by Title
Now showing items 146-165 of 712
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Co‑prevalence of human Papillomaviruses (HPV) and Epstein–Barr virus (EBV) in healthy blood donors from diverse nationalities in Qatar
( BMC , 2020 , Article)Background: Infections by both human oncoviruses, human Papillomaviruses (HPV) and Epstein–Barr virus (EBV) are very common in the adult human population and are associated with various malignancies. While HPV is ... -
A cross-sectional study of the impact of COVID-19 pandemic on the physical activity of Jordanian population
( Wiley-Blackwell , 2022 , Article)Background: Since the declaration of the COVID-19 pandemic on 11th March 2020, the public health recommendations have applied lockdowns and restrictions to limit the spread of the disease. These measures determined outdoor ... -
A Cross-Sectional Study on Bullying and Psychological Disturbances among Malaysian School Children
( Universitas Indonesia , 2021 , Article)Abstract Background: Bullying is a common violence in school and has become a major public health and global concern. Bullying influences mental health and is identified as a leading factor of depression. Therefore, this ... -
Crosstalk Between Oxidative Stress and Endoplasmic Reticulum (ER) Stress in Endothelial Dysfunction and Aberrant Angiogenesis Associated With Diabetes: A Focus on the Protective Roles of Heme Oxygenase (HO)-1
( Frontiers Media , 2019 , Article Review)Type-2 diabetes prevalence is continuing to rise worldwide due to physical inactivity and obesity epidemic. Diabetes and fluctuations of blood sugar are related to multiple micro- and macrovascular complications, that are ... -
Curcumin a Colorimetric and Fluorimetric Cyanide Probe in Aqueous System and Living Cells
( Royal Society of Chemistry , 2019 , Article)Curcumin, 1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-hepta-diene-3,5-dione, is a natural product obtained from the rhizome of Curcuma longa. Curcumin has been demonstrated to be a strong antioxidant with anticancer properties ... -
Curcumin gum Arabic nanoparticles demonstrate potent antioxidant and cytotoxic properties in human cancer cells
( Tech Science Press , 2022 , Article)The main purpose of the study was to enhance the stability and therapeutic effects of Curcumin (Cur) through nanoformulation with gum Arabic (GA) as a coating agent through an efficient synthetic approach. The antioxidant ... -
The Current Status of Cytomegalovirus (CMV) Prevalence in the MENA region: a systematic review
( MDPI , 2019 , Article)Human cytomegalovirus (CMV) is a highly prevalent herpesvirus worldwide. According to the Centers for Disease Control and Prevention (CDC) and the World Health Organization (WHO), CMV infects people of all ages, and by ... -
Current Technologies and Future Perspectives in Immunotherapy towards a Clinical Oncology Approach
( MDPI , 2024 , Article Review)Immunotherapy is now established as a potent therapeutic paradigm engendering antitumor immune response against a wide range of malignancies and other diseases by modulating the immune system either through the stimulation ... -
Current Technologies and Future Perspectives in Immunotherapy towards a Clinical Oncology Approach
( MDPI , 2024 , Article Review)Immunotherapy is now established as a potent therapeutic paradigm engendering antitumor immune response against a wide range of malignancies and other diseases by modulating the immune system either through the stimulation ... -
Cysteamine revisited: repair of arginine to cysteine mutations.
( Springer Verlag , 2017 , Article)Cysteamine is a small aminothiol endogenously derived from coenzyme A degradation. For some decades, synthetic cysteamine has been employed for the treatment of cystinosis, and new uses of the drug continue to emerge. In ... -
Cytoprotective, antioxidant, and anti-migratory activity of Pistacia lentiscus L. supercritical carbon dioxide extract on primary human endothelial cells
( Taylor & Francis , 2022 , Article)Green chemistry is a useful tool for producing valuable chemicals from biomass. However, extracted compounds need to be tested for safety and efficacy before their use in humans. Here we investigate the chemical composition ... -
D-Dimer Concentrations and COVID-19 Severity: A Systematic Review and Meta-Analysis
( Frontiers Media , 2020 , Article Review)Coronavirus disease 2019 (COVID-19) is a recently described infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Since late 2019, COVID-19 has rapidly spread in virtually all countries, ... -
Dasatinib and PD-L1 inhibitors provoke toxicity and inhibit angiogenesis in the embryo
( Elsevier , 2021 , Article)Dasatinib is a targeted cancer therapy, while programmed death ligand 1 (PD-L1) inhibitors are a form of immune checkpoint therapy used to treat various types of cancers. Several studies showed the potential efficacy of ... -
Daytime versus nighttime laparoscopic appendectomy in term of complications and clinical outcomes: A retrospective study of 1001 appendectomies
( Elsevier , 2022 , Article)PurposeThis research aims to study whether the time of day impacts the outcome of laparoscopic appendectomy. Peri/post-operative data including type of surgery, operating room time, length of stay, re-hospitalization rates, ... -
A decade of intestinal protozoan epidemiology among settled immigrants in Qatar
( PubMed Central , 2016 , Article)Background: The World Health Organization estimates that about 3.5 billion people worldwide are affected by intestinal parasitic infections. Reports have already emphasized the role of immigrants in outbreaks of ... -
Deciphering the Role of Filamin B Calponin-Homology Domain in Causing the Larsen Syndrome, Boomerang Dysplasia, and Atelosteogenesis Type I Spectrum Disorders via a Computational Approach.
( MDPI , 2020 , Article)Filamins (FLN) are a family of actin-binding proteins involved in regulating the cytoskeleton and signaling phenomenon by developing a network with F-actin and FLN-binding partners. The FLN family comprises three conserved ... -
Demographic and Clinical Characteristics of Early Travel-Associated COVID-19 Cases
( Frontiers Media , 2020 , Article)© Copyright © 2020 Marei, Emara, Elsaied, Nasrallah, Chivese, Al-Romaihi, Althani, Al Thani, Farag and Yassine. Background: SARS-CoV-2 continues to claim hundreds of thousands of people's lives. It mostly affects the elderly ... -
Demographics and Epidemiology of Hepatitis B in the State of Qatar: A Five-Year Surveillance-Based Incidence Study
( MDPI , 2019 , Article)Background: Expatriates represent >80% of Qatar’s population, mostly arriving from countries in Africa and Asia that are endemic with many diseases. This increases the risk for introducing new pathogens into the country ... -
Dengue and chikungunya seroprevalence among Qatari nationals and immigrants residing in Qatar.
( Public Library of Science , 2019 , Article)The objective of this study is to characterize the seroprevalence of anti-dengue (DENV) and anti-chikungunya (CHIKV) antibodies among blood donors residing in Qatar who are Middle East and North Africa (MENA) nationals and ... -
Description of PTPRG genetic variants identified in a cohort of Chronic Myeloid Leukemia patients and their ability to influence response to Tyrosine kinase Inhibitors
( Elsevier , 2022 , Article)Tyrosine kinase inhibitors (TKIs) have remarkably transformed Ph+ chronic myeloid leukemia (CML) management; however, TKI resistance remains a major clinical challenge. Mutations in BCR-ABL1 are well studied but fail to ...