تصفح Biomedical Sciences حسب الموضوع "aging"
السجلات المعروضة 1 -- 6 من 6
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Inositol 1,4,5-Trisphosphate Receptors in Hypertension.
( Frontiers Media , 2018 , Article Review)Chronic hypertension remains a major cause of global mortality and morbidity. It is a complex disease that is the clinical manifestation of multiple genetic, environmental, nutritional, hormonal, and aging-related disorders. ... -
Investigating the role of functional mutations in leucine binding to Sestrin2 in aging and age-associated degenerative pathologies using structural and molecular simulation approaches
( Taylor & Francis , 2024 , Article)Leucine is the native known ligand of Sestrin2 (Sesn2) and its interaction with Sesn2 is particularly important, as it influences the activity of mTOR in aging and its associated pathologies. It is important to find out ... -
Metabolic signatures of combined exercise and fasting: an expanded perspective on previous telomere length findings
( Frontiers Media SA , 2024 , Article)Introduction: Aging is a complex process marked by a gradual decline in physiological function and increased susceptibility to diseases. Telomere length is frequently regarded as one of the primary biomarkers of aging. ... -
Reduced vasorin enhances angiotensin II signaling within the aging arterial wall
( Impact Journals , 2018 , Article)The glycosylated protein vasorin physically interacts with the transforming growth factor-beta1 (TGF-β1) and functionally attenuates its fibrogenic signaling in the vascular smooth muscle cells (VSMCs) of the arterial wall. ... -
The Role of Systemic Filtrating Organs in Aging and Their Potential in Rejuvenation Strategies
( MDPI , 2022 , Article Review)Advances in aging studies brought about by heterochronic parabiosis suggest that aging might be a reversable process that is affected by changes in the systemic milieu of organs and cells. Given the broadness of such a ... -
Unraveling the Omega-3 Puzzle: Navigating Challenges and Innovations for Bone Health and Healthy Aging
( Multidisciplinary Digital Publishing Institute (MDPI) , 2024 , Article Review)Omega-3 polyunsaturated fatty acids (ω-3 PUFAs, n-3 PUFAs), including eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and alpha-linolenic acid (ALA), are essential polyunsaturated fats primarily obtained from fatty ...
