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Dasatinib and PD-L1 inhibitors provoke toxicity and inhibit angiogenesis in the embryo
(
Elsevier
, 2021 , Article)
Dasatinib is a targeted cancer therapy, while programmed death ligand 1 (PD-L1) inhibitors are a form of immune checkpoint therapy used to treat various types of cancers. Several studies showed the potential efficacy of ...
Neutralization of MERS coronavirus through a scalable nanoparticle vaccine
(
Springer Nature
, 2021 , Article)
MERS-CoV continues to cause human outbreaks, so far in 27 countries worldwide following the first registered epidemic in Saudi Arabia in 2012. In this study, we produced a nanovaccine based on virus-like particles (VLPs). ...
Whole-Genome Sequencing for Molecular Characterization of Carbapenem-Resistant Enterobacteriaceae Causing Lower Urinary Tract Infection among Pediatric Patients
(
MDPI
, 2021 , Article)
Antibiotic resistance is a growing public health problem globally, incurring health and cost
burdens. The occurrence of antibiotic-resistant bacterial infections has increased significantly over the years. Gram-negative ...
SARS-CoV-2 and immune-microbiome interactions: Lessons from respiratory viral infections
(
Elsevier
, 2021 , Article)
By the beginning of 2020, infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) had rapidly evolved into an emergent worldwide pandemic, an outbreak whose unprecedented consequences highlighted ...
Sanguinarine Induces Apoptosis in Papillary Thyroid Cancer Cells via Generation of Reactive Oxygen Species.
(
MDPI
, 2020 , Article)
Sanguinarine (SNG), a natural compound with an array of pharmacological activities, has promising therapeutic potential against a number of pathological conditions, including malignancies. In the present study, we have ...
Prevalence and risk factors of intestinal protozoan infection among symptomatic and asymptomatic populations in rural and urban areas of southern Algeria
(
BMC
, 2021 , Article)
Intestinal parasitic infections are amongst the most common infections worldwide and have been identified as one of the most significant causes of morbidity and mortality among disadvantaged populations. This comparative ...
EndMT regulation by small RNAs in diabetes-associated fibrotic conditions: potential link with oxidative stress
(
Frontiers Media
, 2021 , Article)
Diabetes-associated complications, such as retinopathy, nephropathy, cardiomyopathy, and atherosclerosis, the main consequences of long-term hyperglycemia, often lead to organ dysfunction, disability, and increased mortality. ...
Thymoquinone Suppresses Cell Proliferation and Enhances Apoptosis of HL60 Leukemia Cells through Re-Expression of JAK/STAT Negative Regulators.
(
West Asia Organization for Cancer Prevention (WAOCP)
, 2021 , Article)
The natural compound, thymoquinone (TQ) has demonstrated potential anticancer properties in inhibiting cell proliferation and promoting apoptosis in myeloid leukemia cells, breast cancer cells, and others. However, the ...
Socio-demographic influences on the prevalence of intestinal parasitic infections among workers in Qatar
(
BMC
, 2021 , Article)
The rapid growth of Qatar in the last two decades has been associated with an enormous expansion of building programs in its cities and in the provision of new service industries. This in turn has attracted a large influx ...
Herbal Medicine for Cardiovascular Diseases: Efficacy, Mechanisms, and Safety
(
Frontiers Media S.A.
, 2020 , Article)
Cardiovascular diseases (CVDs) are a significant health burden with an ever-increasing
prevalence. They remain the leading causes of morbidity and mortality worldwide. The use
of medicinal herbs continues to be an ...