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The identification of highly upregulated genes in claudin-low breast cancer through an integrative bioinformatics approach
(
Elsevier
, 2020 , Article)
Breast cancer (BC) is one of the leading causes of cancer-related death among women worldwide, and claudin-low breast cancer (CLBC) is a subtype of BC that remains poorly described. This study aimed to identify upregulated ...
Socio-demographic influences on the prevalence of intestinal parasitic infections among workers in Qatar
(
BMC
, 2021 , Article)
The rapid growth of Qatar in the last two decades has been associated with an enormous expansion of building programs in its cities and in the provision of new service industries. This in turn has attracted a large influx ...
Formulation, Characterization and Biological Activity Screening of Sodium Alginate-Gum Arabic Nanoparticles Loaded with Curcumin.
(
MDPI
, 2020 , Article)
The approach of drug delivery systems emphasizes the use of nanoparticles as a vehicle, offering the optional property of delivering drugs as a single dose rather than in multiple doses. The current study aims to improve ...
Prevalence and Phylogenetic Analysis of Parvovirus (B19V) among Blood Donors with Different Nationalities Residing in Qatar
(
MDPI
, 2021 , Article)
Human parvovirus (B19V) is the causative agent of erythema infectiosum in children and
is linked to a wide range of clinical manifestations. Studies related to B19V prevalence in the Middle
East and North Africa (MENA) ...
SARS-CoV-2 Infection and Smoking: What is the association? A brief review
(
Elsevier
, 2021 , Article)
Susceptibility to severe illness from COVID-19 is anticipated to be associated with cigarette smoking as it aggravates the risk of cardiovascular and respiratory illness, including infections. This is particularly important ...
Genetic Variants Associated With Alzheimer Disease in the 22 Arab Countries: A Systematic Review.
(
Lippincott, Williams & Wilkins
, 2021 , Article)
Alzheimer disease (AD) is a progressive and complex neurodegenerative disease. Approximately 70% of AD risk is attributed to genetic risk factors, including variants in amyloid precursor protein (APP), presenilin 1 (PSEN1), ...
Performance evaluation of five ELISA kits for detecting anti-SARS-COV-2 IgG antibodies
(
Elsevier
, 2020 , Article)
ObjectivesTo evaluate and compare the performances of five commercial ELISA assays (EDI, AnshLabs, Dia.Pro, NovaTec, and Lionex) for detecting anti-SARS-CoV-2 IgG. Methods70 negative control samples (collected before the ...
Comprehensive in silico screening and molecular dynamics studies of missense mutations in Sjogren-Larsson syndrome associated with the ALDH3A2 gene.
(
Elsevier
, 2020 , Article)
Sjögren-Larsson syndrome (SLS) is an autoimmune disorder inherited in an autosomal recessive pattern. To date, 80 missense mutations have been identified in association with the Aldehyde Dehydrogenase 3 Family Member A2 ...
The incidence of the novel coronavirus SARS-CoV-2 among asymptomatic patients: a systematic review
(
Elsevier
, 2020 , Article)
Backgroundthe recent outbreak of the coronavirus disease 2019 (COVID‐19) has quickly spread globally since its discovery in Wuhan, China, in December 2019. A comprehensive strategy, including surveillance, diagnostics, ...
Involvement of Essential Signaling Cascades and Analysis of Gene Networks in Diabesity
(
MDPI
, 2020 , Article)
(1) Aims: Diabesity, defined as diabetes occurring in the context of obesity, is a serious health problem that is associated with an increased risk of premature heart attack, stroke, and death. To date, a key challenge has ...