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CD44 mediates stem cell mobilization to damaged lung via its novel transcriptional targets, Cortactin and Survivin
(
Ivyspring International Publisher
, 2020 , Article)
Beyond their role in bone and lung homeostasis, mesenchymal stem cells (MSCs) are becoming popular in cell therapy. Various insults may disrupt the repair mechanisms involving MSCs. One such insult is smoking, which is a ...
Vaccine Development Against COVID-19 Prior to Pandemic Outbreaks, Using in vitro Evolution and Reverse Genetics
(
Frontiers Media
, 2020 , Article)
Developing vaccines against COVID-19 during or after future pandemic outbreaks will be too slow to save lives. The opinion presented here is that we can anticipate the virus genomic structures that will emerge and cause ...
Fasting Ramadan During COVID-19 Pandemic: Immunomodulatory Effect
(
Frontiers Media S.A.
, 2020 , Article)
As of April 24, 2020, more than 1. 6 billion Muslims observe the holy fasting month of Ramadan worldwide. The safety of fasting of healthy adult Muslims during the COVID-19 era is debatable. In this perspective, we discuss ...
D-Dimer Concentrations and COVID-19 Severity: A Systematic Review and Meta-Analysis
(
Frontiers Media
, 2020 , Article Review)
Coronavirus disease 2019 (COVID-19) is a recently described infectious disease caused
by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Since late 2019,
COVID-19 has rapidly spread in virtually all countries, ...
Estrogen and Bisphenol A in Hypertension
(
Springer
, 2020 , Article Review)
Purpose of Review: Cardiovascular disease (CVD) is a non-subsiding disease that remains a leading cause of morbidity and mortality. CVD has been associated with endocrine disruptors, such as bisphenol A (BPA). This review ...
Drosophila as a Model Organism in Host–Pathogen Interaction Studies
(
Frontiers Media
, 2020 , Article Review)
Owing to the genetic similarities and conserved pathways between a fruit fly and mammals, the use of the Drosophila model as a platform to unveil novel mechanisms of infection and disease progression has been justified and ...
Potential Therapeutic Effects of Sodium Glucose-linked Cotransporter 2 Inhibitors in Stroke
(
Elsevier
, 2020 , Article Review)
Purpose: Stroke is the second leading cause of death and the third leading cause of disability worldwide. Diabetes mellitus and the associated hyperglycemia are important risk factors for acute ischemic stroke and are ...
Western diet aggravates neuronal insult in post-traumatic brain injury: Proposed pathways for interplay
(
Elsevier
, 2020 , Article Review)
Traumatic brain injury (TBI) is a global health burden and a major cause of disability and mortality. An early cascade of physical and structural damaging events starts immediately post-TBI. This primary injury event ...
Novel therapeutic strategies for spinal osteosarcomas
(
Elsevier
, 2020 , Article Review)
At the dawn of the third millennium, cancer has become the bane of twenty-first century man, and remains a predominant public health burden, affecting welfare and life expectancy globally. Spinal osteogenic sarcoma, a ...
Measuring influenza hemagglutinin (HA) stem-specific antibody-dependent cellular cytotoxicity (ADCC) in human sera using novel stabilized stem nanoparticle probes
(
Elsevier
, 2020 , Article)
Background: Generating vaccine that confers a complete protection is a major goal in designing a universal influenza vaccine. Currently, there is a considerable interest in the broadly neutralizing antibodies (bnAb) targeting ...