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Now showing items 11-20 of 27
Activation of the pro-oxidant PKC?IIp66Shc Signaling pathway contributes to pericyte dysfunction in skeletal muscles of patients with diabetes with critical limb Ischemia
(
American Diabetes Association Inc.
, 2016 , Article)
Critical limb ischemia (CLI), foot ulcers, former amputation, and impaired regeneration are independent risk factors for limb amputation in subjects with diabetes. The present work investigates whether and by which mechanism ...
Activation of the Pro-Oxidant PKCβII-p66Shc Signaling Pathway Contributes to Pericyte Dysfunction in Skeletal Muscles of Diabetic Patients with Critical Limb Ischemia
(
American Diabetes Association
, 2016 , Article)
Critical limb ischemia (CLI), foot ulcers, former amputation and impaired regeneration are independent risk factors for limb amputation in diabetic subjects. The present work investigates whether and by which mechanism ...
Metabolic shift toward oxidative phosphorylation in docetaxel resistant prostate cancer cells
(
Impact Journals
, 2016 , Article)
Drug resistance of cancer cells is recognized as the primary cause of failure of chemotherapeutic treatment in most human cancers. Growing evidences support the idea that deregulated cellular metabolism is linked to such ...
Identification of the Main Intermediate Precursor of l-Ergothioneine Biosynthesis in Human Biological Specimens
(
MDPI AG
, 2016 , Article)
A capillary electrophoresis coupled to tandem mass spectrometry (CE–MS/MS) has been used to make a qualitative determination of hercynine—the main precursor of l-ergothioneine biosynthesis—in some key human biological ...
Strategies to enhance graphic and results interpretation of a regression-based approach for method comparison studies.
(
Future Science Ltd
, 2017 , Article)
To improve the effectiveness of a previous regression-based approach for the assessment of the agreement between different analytical methods, two modifications/integrations to the original scheme by means of log10 ...
Cellular immune activation in Sardinian middle-aged, older adults and centenarians
(
Elsevier
, 2017 , Article)
In addition to viral infections, malignant disorders, autoimmune diseases, and allograft rejection episodes, neopterin increases in older people where it is found to be predictive of overall mortality. Thus, the serum ...
Ecotoxicological Assessment of Thermally- and Hydrogen-Reduced Graphene Oxide/TiO₂ Photocatalytic Nanocomposites Using the Zebrafish Embryo Model.
(
MDPI
, 2019 , Article)
Advanced oxidation processes (AOPs) have recently attracted great interest in water pollution management. Using the zebrafish embryo model, we investigated the environmental impacts of two thermally (RGOTi)- and hydrogen ...
Immunogenetics of Celiac Disease: A focus on Arab countries.
(
Bentham Science Publishers
, 2019 , Article)
Celiac Disease (CD) is a complex immunogenic disease mainly triggered by gluten intake in genetically susceptible individuals with a prevalence of 1 in 100-300. CD results from the interplay between genetic and environmental ...
Marjoram Relaxes Rat Thoracic Aorta Via a PI3-K/eNOS/cGMP Pathway.
(
MDPI
, 2019 , Article)
Despite pharmacotherapeutic advances, cardiovascular disease (CVD) remains the primary cause of global mortality. Alternative approaches, such as herbal medicine, continue to be sought to reduce this burden. is recognized ...
Flavin Oxidase-Induced ROS Generation Modulates PKC Biphasic Effect of Resveratrol on Endothelial Cell Survival.
(
MDPI
, 2019 , Article)
Dietary intake of natural antioxidants is thought to impart protection against oxidative-associated cardiovascular diseases. Despite many in vivo studies and clinical trials, this issue has not been conclusively resolved. ...