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Assessing the burden of intestinal parasites affecting newly arrived immigrants in Qatar
(
BioMed Central
, 2016 , Article)
In the last decades, the enormous influx of immigrants to industrialized countries has led to outbreaks of parasitic diseases, with enteric infections being amongst the most frequently encountered. In its strategy to control ...
Associations of Vitamin D Receptor Polymorphism rs1544410 with Adiposity Phenotypes
(
MedCrave
, 2016 , Article)
Background: Vitamin D receptor (VDR) is present on adipocytes, and many studies were performed to investigate the association between polymorphisms in VDR gene with obesity. However, in the Arab Gulf populations, whereas ...
Prevalence of anelloviruses (TTV, TTMDV, and TTMV) in healthy blood donors and in patients infected with HBV or HCV in Qatar
(
BioMed Central
, 2016 , Article)
Background
Anelloviruses (TTV, TTMV, and TTMDV) have been associated with non A-G hepatitis. The goal of the current study was to estimate the prevalence of these anelloviruses in Qatar.
Methods
A total of 607 blood ...
Genetic Epidemiology of Glucose-6-Dehydrogenase Deficiency in the Arab World
(
Nature Publishing Group
, 2016 , Article)
A systematic search was implemented using four literature databases (PubMed, Embase, Science Direct and Web of Science) to capture all the causative mutations of Glucose-6-phosphate dehydrogenase (G6PD) deficiency (G6PDD) ...
Mendelian inheritance of trimodal CpG methylation sites suggests distal cis-acting genetic effects.
(
BioMed Central
, 2016 , Article)
Environmentally influenced phenotypes, such as obesity and insulin resistance, can be transmitted over multiple generations. Epigenetic modifications, such as methylation of DNA cytosine-guanine (CpG) pairs, may be carriers ...
Prevalence of Virulence/Stress Genes in Campylobacter jejuni from Chicken Meat Sold in Qatari Retail Outlets
(
Public Library of Science
, 2016 , Article)
Chicken meat from the shelves of supermarkets in Qatar was tested for the presence of
Campylobacter spp. and the presence of five virulence genes (htrB, cdtB, clpP, cadF and
ciaB) was assessed in isolates. Forty eight ...
Metabolic shift toward oxidative phosphorylation in docetaxel resistant prostate cancer cells
(
Impact Journals
, 2016 , Article)
Drug resistance of cancer cells is recognized as the primary cause of failure of chemotherapeutic treatment in most human cancers. Growing evidences support the idea that deregulated cellular metabolism is linked to such ...
Helminth infections among long-term residents and settled immigrants in Qatar in the decade from 2005 to 2014: temporal trends and varying prevalence among subjects from different regional origins
(
BioMed Central
, 2016 , Article)
Background: Travel and migration from developing regions, where tropical diseases are common, to more developed
industrialised nations can contribute to the introduction and subsequent spread of infections. With its rapidly ...
Identification of the Main Intermediate Precursor of l-Ergothioneine Biosynthesis in Human Biological Specimens
(
MDPI AG
, 2016 , Article)
A capillary electrophoresis coupled to tandem mass spectrometry (CE–MS/MS) has been used to make a qualitative determination of hercynine—the main precursor of l-ergothioneine biosynthesis—in some key human biological ...
Bidirectional communication between the Aryl hydrocarbon Receptor (AhR) and the microbiome tunes host metabolism
(
Nature Publishing Group in partnership with Nanyang Technological University
, 2016 , Article)
The ligand-induced transcription factor, aryl hydrocarbon receptor (AhR) is known for its capacity to tune adaptive immunity and xenobiotic metabolism-biological properties subject to regulation by the indigenous microbiome. ...