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Zebrafish (Danio rerio) as a Model for the Study of Developmental and Cardiovascular Toxicity of Electronic Cigarettes
(
MDPI
, 2023 , Article Review)
The increasing popularity of electronic cigarettes (e-cigarettes) as an alternative to conventional tobacco products has raised concerns regarding their potential adverse effects. The cardiovascular system undergoes intricate ...
Traumatic brain injury: Oxidative stress and novel anti-oxidants such as mitoquinone and edaravone
(
MDPI
, 2020 , Article Review)
Traumatic brain injury (TBI) is a major health concern worldwide and is classified based on severity into mild, moderate, and severe. The mechanical injury in TBI leads to a metabolic and ionic imbalance, which eventually ...
Biochemical and cellular basis of oxidative stress: Implications for disease onset
(
Wiley
, 2023 , Article Review)
Cellular oxidation–reduction (redox) systems, which encompass pro- and antioxidant molecules, are integral components of a plethora of essential cellular processes. Any dysregulation of these systems can cause molecular ...
Association between metabolically healthy obesity and metastasis in lung cancer patients – a systematic review and meta-analysis
(
Frontiers Media
, 2023 , Article Review)
Background: Many clinical trials have looked at the relationship between obesity and lung cancer (LC), however, there is scarcity of literature specifically addressing the association between metabolically healthy obesity ...
Metabolomics Approaches for the Diagnosis, Treatment, and Better Disease Management of Viral Infections
(
MDPI
, 2023 , Article Review)
Metabolomics is an analytical approach that involves profiling and comparing the metabolites present in biological samples. This scoping review article offers an overview of current metabolomics approaches and their ...
The Immunomodulatory Role of Microbiota in Rheumatic Heart Disease: What Do We Know and What Can We Learn from Other Rheumatic Diseases?
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2023 , Article Review)
Rheumatic heart disease (RHD) represents a serious cardiac sequela of acute rheumatic fever, occurring in 30-45% of patients. RHD is multifactorial, with a strong familial predisposition and known environmental risk factors ...
Impact of the MIF -173G/C variant on cardiovascular disease risk: a meta-analysis of 9,047 participants
(
Frontiers Media SA
, 2024 , Article Review)
Introduction: Many factors contribute to the risk of cardiovascular disease (CVD), an umbrella term for several different heart diseases, including inflammation. Macrophage migration inhibitory factor (MIF) is an important ...
Biomaterials in Traumatic Brain Injury: Perspectives and Challenges
(
MDPI
, 2023 , Article Review)
Traumatic brain injury (TBI) is a leading cause of mortality and long-term impairment globally. TBI has a dynamic pathology, encompassing a variety of metabolic and molecular events that occur in two phases: primary and ...
Breaking Barriers: The Promise and Challenges of Immune Checkpoint Inhibitors in Triple-Negative Breast Cancer
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2024 , Article Review)
Triple-negative breast cancer (TNBC) is a highly aggressive malignancy with pronounced immunogenicity, exhibiting rapid proliferation and immune cell infiltration into the tumor microenvironment. TNBC’s heterogeneity poses ...
Organoboronic acids/esters as effective drug and prodrug candidates in cancer treatments: challenge and hope
(
Taylor and Francis Ltd.
, 2023 , Article Review)
Boronic acids/esters have recently emerged in the field of medicinal and pharmaceutical research due to their exceptional oxophilicity, low toxicity, and unique structure. They are known as potent enzyme inhibitors, cancer ...