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Using Zebrafish for Investigating the Molecular Mechanisms of Drug-Induced Cardiotoxicity
(
Hindawi Publishing Corporation
, 2018 , Article)
Over the last decade, the zebrafish (Danio rerio) has emerged as amodel organismfor cardiovascular research.Zebrafish have several advantages over mammalian models. For instance, the experimental cost of using zebrafish ...
Effect of Water-Pipe Smoking on the Normal Development of Zebrafish
(
MDPI
, 2021 , Article)
Background: Among all types of tobacco consumption,Water-Pipe Smoking (WPS) is the
most widely used in the Middle East and second-most in several other countries. The effect of WPS
on normal development is not yet fully ...
Reduced Cardiotoxicity of Ponatinib-Loaded PLGA-PEG-PLGA Nanoparticles in Zebrafish Xenograft Model.
(
MDPI
, 2022 , Article)
Tyrosine kinase inhibitors (TKIs) are the new generation of anti-cancer drugs with high potential against cancer cells' proliferation and growth. However, TKIs are associated with severe cardiotoxicity, limiting their ...
Zebrafish as a Model for Anticancer Nanomedicine Studies.
(
MDPI
, 2021 , Article Review)
Nanomedicine is a new approach to fight against cancer by the development of anticancer nanoparticles (NPs) that are of high sensitivity, specificity, and targeting ability to detect cancer cells, such as the ability of ...
Developmental Toxicity of Surface-Modified Gold Nanorods in the Zebrafish Model
(
American Chemical Society
, 2022 , Article)
Background: nanotechnology is one of the fastest-growing areas, and it is expected to have a substantial economic and social impact in the upcoming years. Gold particles (AuNPs) offer an opportunity for wide-ranging ...
Functional characterization of human myosin-binding protein C3 variants associated with hypertrophic cardiomyopathy reveals exon-specific cardiac phenotypes in zebrafish model
(
Wiley
, 2020 , Article)
© 2020 Wiley Periodicals, Inc. Myosin-binding protein C 3 (MYBPC3) variants are the most common cause of hypertrophic cardiomyopathy (HCM). HCM is a complex cardiac disorder due to its significant genetic and clinical ...