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    mRNA-1273 COVID-19 vaccine effectiveness against the B.1.1.7 and B.1.351 variants and severe COVID-19 disease in Qatar 

    Chemaitelly, Hiam; Yassine, Hadi M.; Benslimane, Fatiha M.; Al Khatib, Hebah A.; Tang, Patrick; Hasan, Mohammad R.; Malek, Joel A.; Coyle, Peter; Ayoub, Houssein H.; Al Kanaani, Zaina; Al Kuwari, Einas; Jeremijenko, Andrew; Kaleeckal, Anvar Hassan; Latif, Ali Nizar; Shaik, Riyazuddin Mohammad; Abdul Rahim, Hanan F.; Nasrallah, Gheyath K.; Al Kuwari, Mohamed Ghaith; Al Romaihi, Hamad Eid; Al-Thani, Mohamed H.; Al Khal, Abdullatif; Butt, Adeel A.; Bertollini, Roberto; Abu-Raddad, Laith J.... more authors ... less authors (2021 , Article)
    The SARS-CoV-2 pandemic continues to be a global health concern. The mRNA-1273 (Moderna) vaccine was reported to have an efficacy of 94.1% at preventing symptomatic COVID-19 due to infection with ‘wild-type’ variants in a ...
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    Effectiveness of the BNT162b2 Covid-19 Vaccine against the B.1.1.7 and B.1.351 Variants. 

    Abu-Raddad, Laith J; Chemaitelly, Hiam; Butt, Adeel A ( Massachusetts Medical Society , 2021 , Other)
    The messenger RNA vaccine BNT162b2 (Pfizer–BioNTech) has 95% efficacy against coronavirus disease 2019 (Covid-19). Qatar launched a mass immunization campaign with this vaccine on December 21, 2020. As of March 31, 2021, ...
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    Involvement of caveolae in hyperglycemia-induced changes in adiponectin and leptin expressions in vascular smooth muscle cells 

    Ola, El Atab; Ghantous, Crystal M.; El-Zein, Nabil; Farhat, Rima; Agouni, Abdelali; Korashy, Hesham M.; Djouhri, Laiche; Kamareddine, Layla; Zibara, Kazem; Zeidan, Asad... more authors ... less authors ( Elsevier , 2021 , Article)
    Hyperglycemia exerts various harmful effects on the vasculature. Studies have shown an association between the levels of the adipokines leptin and adiponectin (APN) and vascular complications in diabetes mellitus. The aim ...
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    Estrogen increases expression of vascular alpha 2C adrenoceptor through the cAMP/Epac/JNK/AP-1 pathway and potentiates cold-induced vasoconstriction 

    Fardoun, Manal M.; Issa, Khodr; Maaliki, Dina; Nasser, Suzanne A.; Baydoun, Elias; Eid, Ali H.... more authors ... less authors ( Elsevier , 2020 , Article)
    Cutaneous cold-induced vasoconstriction is a normal physiological reaction mediated by alpha 2C-adrenergic receptors (α2C-ARs) expressed in vascular smooth muscle cells (VSMCs). When this reaction is exaggerated, Raynaud's ...
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    The hypertensive potential of estrogen: An untold story 

    Fardoun, Manal; Dehaini, Hassan; Shaito, Abdallah; Mesmar, Joelle; El-Yazbi, Ahmed; Badran, Adnan; Beydoun, Elias; Eid, Ali H.... more authors ... less authors ( Elsevier , 2020 , Article Review)
    Cardiovascular disease (CVD) is the major cause of morbidity and mortality worldwide. The implication of estrogen in this disease has been extensively studied. While the vast majority of published research argue for a ...
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    Flavonoids in adipose tissue inflammation and atherosclerosis: One arrow, two targets 

    Fardoun, Manal Muin; Maaliki, Dina; Halabi, Nabil; Iratni, Rabah; Bitto, Alessandra; Baydoun, Elias; Eid, Ali H.... more authors ... less authors ( Portland Press Ltd , 2020 , Article Review)
    Flavonoids are polyphenolic compounds naturally occurring in fruits and vegetables, in addition to beverages such as tea and coffee. Flavonoids are emerging as potent therapeutic agents for cardiovascular as well as metabolic ...
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    SARS-CoV-2 infection among primary healthcare workers: a cross- sectional study 

    Qotba, Hamda; Hamed, Ehab; Alnuaimi, Ahmed; Saad, Azza; Nasrallah, Gheyath; Alnaama, Abdulla; Syed, Mohamed... more authors ... less authors ( GERMS , 2021 , Article)
    Healthcare workers (HCWs) are critical to the healthcare system and are at an increased risk of SARS-CoV-2 infection. They may acquire infections from the community and their work settings. To date, the majority of the ...
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    A computational overview on phylogenetic characterization, pathogenic mutations, and drug targets for Ebola virus disease 

    Vasudevan, Karthick; D, Thirumal Kumar; S, Udhaya Kumar; Saleem, Aisha; N, Nagasundaram; R, Siva; Tayubi, Iftikhar Aslam; Doss, C. George Priya; Zayed, Hatem... more authors ... less authors ( Elsevier , 2021 , Article)
    The World Health Organization declared Ebola virus disease(EVD) as the major outbreak in the 20th century. EVD was firstidentified in 1976 in South Sudan and the Democratic Republicof the Congo. EVD was transmitted from ...
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    Comparison of potential inhibitors and targeting fat mass and obesity-associated protein causing diabesity through docking and molecular dynamics strategies. 

    S, Udhaya Kumar; Rajan, Bithia; D, Thirumal Kumar; R, Hephzibah Cathryn; V, Samprita Das.; Zayed, Hatem; Walter, Charles Emmanuel Jebaraj; Ramanathan, Gnanasambandan; Doss, George Priya... more authors ... less authors ( Wiley , 2021 , Article)
    Genome-wide association studies (GWAS) have identified an association between polymorphisms in the FTO gene and obesity. The FTO: rs9939609, an intronic variant, is considered a risk allele for developing diabesity in ...
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    A systemic approach to explore the mechanisms of drug resistance and altered signaling cascades in extensively drug-resistant tuberculosis 

    Udhaya Kumar, S.; Saleem, Aisha; Thirumal Kumar, D.; Anu Preethi, V.; Younes, Salma; Zayed, Hatem; Tayubi, Iftikhar Aslam; George Priya Doss, C.... more authors ... less authors ( Elsevier , 2021 , Book chapter)
    Background and aim: The persistence of extensively drug-resistant (XDR) strains of Mycobacterium tuberculosis (MTB) continue to pose a significant challenge to the treatment and control of tuberculosis infections worldwide. ...
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      Zayed, Hatem (14) George Priya Doss, C (4) Younes, Salma (4) D, Thirumal Kumar (3) ... View More
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      Article (21) Article Review (6) Book chapter (3) Other (1)
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      Estrogen (4) cancer (2) Cardiovascular disease (2) Cytokines (2) ... View More
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