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The Contribution Of Toll-Like Receptors In The Pathogenesis Of Diabetic Retinopathy In Human Microvascular Retinal Endothelial Cells In Vitro
(Biomedical Sciences, 2016 , Master Thesis)
Background: Diabetes Mellitus is a chronic systemic inflammatory disease including the eye causing macrovascular as well as microvascular complications known as diabetic retinopathy (DR), thus increasing the risk of vision ...
Performance Evaluation for the HBVAND HCV Detection Protocols That Are Used By the Medical Commission Diagnostic Laboratory in Qatar
(Biomedical sciences, 2020 , Master Thesis)
Background: Viral Hepatitis is regarded as a serious concern to human wellbeing,
affecting millions of individuals yearly. The leading cause of this disease is the
infection of Hepatitis A, B, C, D, and E. Consequently, ...
Performance Evaluation for the HIV And Syphilis Detection Protocols Used By The Medical Commission Diagnostic Laboratory In Qatar
(Biomedical sciences, 2020 , Master Thesis)
Background: The Medical Commission is responsible for screening all newcomers and
expatriates in Doha, Qatar to ensure that infectious diseases do not enter the country.
The infectious disease tests include; HIV, ...
ANTIMICROBIAL RESISTANCE OF COMMENSAL ESCHERICHIA COLI ISOLATED FROM FOOD ANIMALS IN QATAR
(Biomedical Sciences, 2019 , Master Thesis)
Background: The dissemination of antimicrobial resistance (AMR) bacteria is associated with the inappropriate use of antibiotics in both humans and animals. In particular, the use of antibiotics for prophylactic and growth ...
VISUALIZATION OF FACTOR VIII WITH FLOW-CYTOMETRY AS A TOOL FOR NOVEL GENE THERAPY APPROACH IN HEMOPHILIA A
(Biomedical Sciences, 2019 , Master Thesis)
Haemophilia A is a genetic X-linked disorder, characterized by coagulation Factor VIII (FVIII) deficiency and leading to pathological bleedings. The disease occurs in a rate of 1 in 5000 males’ births. The treatment is the ...
ANTI-CANCER ACTIVITY OF SANGUINARINE ON HUMAN PAPILLARY THYROID CANCER CELL LINES BY TARGETING JAK/STAT3 PATHWAY
(Biomedical Sciences, 2021 , Master Thesis)
Background: Papillary thyroid carcinoma is the furthermost common type of thyroid
cancer, representing 85 % of all thyroid cancer cases. It occurs more frequently in
women and usually affects 20-55 year age group. Aim: ...
Latent Tuberculosis Infection Among Health Care Workers At The Communicable Disease Center In Qatar: Prevalence And Determinants
(Biomedical Sciences, 2019 , Master Thesis)
Background: To estimate the prevalence of latent Pulmonary Tuberculosis infection among healthcare workers in Communicable Disease Center (CDC) in Qatar and explore the factors associated with latent tuberculosis infection ...
NASAL EXPRESSION OF ANIOTENSIN-CONVERTING ENZYME 2 (ACE2) IN CHILDREN AND ADULTS WITH COVID-19
(Biomedical Sciences, 2021 , Master Thesis)
"Emerging evidence suggests that the lower expression of SARS-CoV-2 entry factor angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2) in the nasal epithelium of children may contribute to ...
DEVELOPMENT AND IN VIVO TESTING OF SMART NANOPARTICLES FOR ENHANCED ANTI-CANCER ACTIVITY AND REDUCED CARDIOTOXICITY ASSOCIATED WITH TYROSINE KINASE INHIBITORS
(Biomedical Sciences, 2021 , Master Thesis)
Tyrosine kinase inhibitors (TKIs) are new generation of anti-cancer drugs with very high efficiency against cancer cells. However, TKIs are associated with severe cardiotoxicity limiting their clinical benefits. One ...
THE IMPACT OF HSA-MIR-146A-5P ON HUMAN RETINAL ENDOTHELIAL CELLS IN DIABETIC CONDITIONS
(Biomedical Sciences, 2021 , Master Thesis)
Background: Diabetic retinopathy (DR) is a microvascular complication of diabetes that leads to visual impairment in the adult population with effective available therapy. Micro-Ribonucleic acids (miRNAs) are small (?22 ...