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NASAL EXPRESSION OF ANIOTENSIN-CONVERTING ENZYME 2 (ACE2) IN CHILDREN AND ADULTS WITH COVID-19
(Biomedical Sciences, 2021 , Master Thesis)
"Emerging evidence suggests that the lower expression of SARS-CoV-2 entry factor angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2) in the nasal epithelium of children may contribute to ...
VISUALIZATION OF FACTOR VIII WITH FLOW-CYTOMETRY AS A TOOL FOR NOVEL GENE THERAPY APPROACH IN HEMOPHILIA A
(Biomedical Sciences, 2019 , Master Thesis)
Haemophilia A is a genetic X-linked disorder, characterized by coagulation Factor VIII (FVIII) deficiency and leading to pathological bleedings. The disease occurs in a rate of 1 in 5000 males’ births. The treatment is the ...
ANTIMICROBIAL RESISTANCE OF COMMENSAL ESCHERICHIA COLI ISOLATED FROM FOOD ANIMALS IN QATAR
(Biomedical Sciences, 2019 , Master Thesis)
Background: The dissemination of antimicrobial resistance (AMR) bacteria is associated with the inappropriate use of antibiotics in both humans and animals. In particular, the use of antibiotics for prophylactic and growth ...
ASSESSMENT OF GNAS LOSS OF FUNCTION IN MONOGENIC OBESITY USING THE ZEBRAFISH MODEL
(Biomedical Sciences, 2024 , Master Thesis)
GNAS (Guanine Nucleotide-Binding Protein, Alpha Stimulating) is an imprinted gene that encodes the alpha subunit of the stimulatory G protein (Gs), which participates in the signaling of various G protein-coupled receptors. ...
ASSESSING THE CURRENT STANDING OF HAMAD MEDICAL CORPORATION BLOOD DONOR CENTER IN QATAR AND DEVELOPING A FORECAST MODEL FOR THE BLOOD STOCK NEEDS DURING THE 2022 WORLD CUP EVENT
(Biomedical Sciences, 2019 , Master Thesis)
Background: In four years from now, Qatar will host the 2022 World Cup competition which requires high level of preparedness and readiness in different sectors including health care. Among different sub-sections of health, ...
ANTI-CANCER ACTIVITY OF SANGUINARINE ON HUMAN PAPILLARY THYROID CANCER CELL LINES BY TARGETING JAK/STAT3 PATHWAY
(Biomedical Sciences, 2021 , Master Thesis)
Background: Papillary thyroid carcinoma is the furthermost common type of thyroid
cancer, representing 85 % of all thyroid cancer cases. It occurs more frequently in
women and usually affects 20-55 year age group. Aim: ...
Vascular Endothelial Dysfunction as the Mechanism for Development of Obesity
(Biomedical Sciences, 2018 , Master Thesis)
Obesity is one of the major public health issues in the world with a rapid increase
in its prevalence. According to the last public health report from supreme public health in
Qatar in 2012, 71.8 % of the women were ...
Investigating the Validity and Significance of Variant Calls by Next Generation Sequencing (NGS)
(Biomedical Sciences, 2016 , Master Thesis)
Whole genome or exome sequencing enables the fast generation of large volumes of data and is currently a hot topic in research. This technique has the subject of extensive research and has vast applications in healthcare ...
TRANSCRIPTIONAL CHANGES OF MYCOPLASMA CONTAMINATION IN GENE EXPRESSION STUDIES
(Biomedical Sciences, 2016 , Master Thesis)
Mycoplasma, the smallest self-replicating microorganism, is one of the most significant problems in the cell-culture field. It characterized by the absence of the cell wall, causing resistance to commonly used antibiotics ...
IN-DEPTH CHARACTERIZATION OF MESENCHYMAL STEM CELLS-DERIVED EXTRACELLULAR VESICLES USING QUANTITATIVE PROTEOMICS
(Biomedical Sciences, 2016 , Master Thesis)
As they home in on injured tissue, modulate the immune system and support tissue repairing, mesenchymal stem cells (MSCs) are considered a promising tool for many therapeutic applications. In vitro, MSCs have been shown ...