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Investigating the Validity and Significance of Variant Calls by Next Generation Sequencing (NGS)
(Biomedical Sciences, 2016 , Master Thesis)
Whole genome or exome sequencing enables the fast generation of large volumes of data and is currently a hot topic in research. This technique has the subject of extensive research and has vast applications in healthcare ...
TRANSCRIPTIONAL CHANGES OF MYCOPLASMA CONTAMINATION IN GENE EXPRESSION STUDIES
(Biomedical Sciences, 2016 , Master Thesis)
Mycoplasma, the smallest self-replicating microorganism, is one of the most significant problems in the cell-culture field. It characterized by the absence of the cell wall, causing resistance to commonly used antibiotics ...
IN-DEPTH CHARACTERIZATION OF MESENCHYMAL STEM CELLS-DERIVED EXTRACELLULAR VESICLES USING QUANTITATIVE PROTEOMICS
(Biomedical Sciences, 2016 , Master Thesis)
As they home in on injured tissue, modulate the immune system and support tissue repairing, mesenchymal stem cells (MSCs) are considered a promising tool for many therapeutic applications. In vitro, MSCs have been shown ...
The Contribution Of Toll-Like Receptors In The Pathogenesis Of Diabetic Retinopathy In Human Microvascular Retinal Endothelial Cells In Vitro
(Biomedical Sciences, 2016 , Master Thesis)
Background: Diabetes Mellitus is a chronic systemic inflammatory disease including the eye causing macrovascular as well as microvascular complications known as diabetic retinopathy (DR), thus increasing the risk of vision ...
SEROPREVALENCE AND PHYLOGENETIC GENOTYPING OF EPSTEIN BARR VIRUS (EBV) AMONG BLOOD DONORS IN QATAR
(Biomedical Sciences, 2016 , Master Thesis)
Background: EBV is a lymphotropic herpesvirus and the causative agent of infectious mononucleosis. EBV is highly prevalent and has been linked to several malignancies. The virus is generally transferred by oral secretions ...
EFFECT OF ENDOPLASMIC RETICULUM STRESS MEDIATED BY HYPERGLYCEMIA ON BARRIER FUNCTION IN RETINAL CELLS
(Biomedical Sciences, 2016 , Master Thesis)
Background: Diabetic Retinopathy (DR) is an inflammatory disease mainly characterized by the dysfunction of the retinal blood vessels. Several studies reported a possible link between the hyperglycemia and the activation ...