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Molecular Analysis Of The Brca1 And Brca2 Genes In Hereditary Breast Or Ovarian Cancer Patients In Qatar (2015-2016)
(Biomedical Sciences, 2018 , Master Thesis)
The frequency of BRCA1 and BRCA2 mutations is understudied in Arab women
and there are no studies investigating BRCA1/2 mutations in Qatar. In this study, we
sequenced BRCA1 and BRCA2 genes in 183 patients suspected of ...
The Expression of Retinal miRNA Evoked by Hyperglycemia and After Adiponectin Treatment in Human Retinal Endothelial Cells
(Biomedical Sciences, 2018 , Master Thesis)
Background: Diabetes mellitus is a chronic metabolic disease resulting in microvascular complications including diabetic retinopathy (DR). Adiponectin (ApN) is an adipokine hormone, and recent studies demonstrated that ApN ...
Profiling of Chronic Myeloid Neoplasms through RNA Sequencing Analysis
(Biomedical Sciences, 2018 , Master Thesis)
Background: Chronic myeloid leukemia (CML) is a clonal myeloproliferative disorder resulting from the neoplastic transformation of hematopoietic stem cells. A higher number of (54%) CML patients in Qatar failed to respond ...
TEST UTILIZATION PRACTICES IN HAMAD MEDICAL CORPORATION: LABORATORIES AND CLINICIANS
(Biomedical Sciences, 2018 , Professional Masters Project)
Background Improper test utilization is a common problem of all healthcare systems. It
costs vast amount of money without improving the patient care. There are three types of
this inappropriate utilization of laboratory ...
Characterization Of Genomic Alterations And Tcrβ Repertoire Of Tumor- Infiltrating Lymphocytes In Breast Cancer
(Biomedical Sciences, 2018 , Master Thesis)
Breast cancer still remains a major cause of morbidity and mortality among
women in Qatar and worldwide. More recent studies indicate that the diversity and
the composition of the entire set of antigen receptors within ...
National Study of Anaphylaxis in a Large Tertiary Care Hospital in Qatar: A Retrospective Study
(Biomedical Sciences, 2018 , Master Thesis)
Background: Anaphylaxis is a serious systemic allergic disease that often mani-fests with a broad array of symptoms and leads to death if not immediately treated by the administration of epinephrine auto-injector (EAI). ...
Magnitude of RSV Fusion Protein-Specific Antibodies in Infants and Corresponding Mothers
(Biomedical Sciences, 2018 , Master Thesis)
INTRODUCTION: Respiratory syncytial virus (RSV) is a threatening agent causing lower respiratory infections (LRI) among children, where no vaccine is available. RSV expresses three surface glycoproteins, of which the ...
Vascular Endothelial Dysfunction as the Mechanism for Development of Obesity
(Biomedical Sciences, 2018 , Master Thesis)
Obesity is one of the major public health issues in the world with a rapid increase
in its prevalence. According to the last public health report from supreme public health in
Qatar in 2012, 71.8 % of the women were ...