Slippery liquid-infused porous polymeric surfaces based on natural oil with antimicrobial effect
Author | Habib, S. |
Author | Zavahir, S. |
Author | Abusrafa, A.E. |
Author | Abdulkareem, A. |
Author | Sobolciak, P. |
Author | Lehocky, M. |
Author | Vesela, D. |
Author | Humpolicek, P. |
Author | Popelka, A. |
Available date | 2023-10-09T07:34:21Z |
Publication Date | 2021 |
Publication Name | Polymers |
Resource | Scopus |
Abstract | Many polymer materials have found a wide variety of applications in biomedical indus-tries due to their excellent mechanical properties. However, the infections associated with the bio-film formation represent serious problems resulting from the initial bacterial attachment on the polymeric surface. The development of novel slippery liquid-infused porous surfaces (SLIPSs) repre-sents promising method for the biofilm formation prevention. These surfaces are characterized by specific microstructural roughness able to hold lubricants inside. The lubricants create a slippery layer for the repellence of various liquids, such as water and blood. In this study, effective antimi-crobial modifications of polyethylene (PE) and polyurethane (PU), as commonly used medical pol-ymers, were investigated. For this purpose, low-temperature plasma treatment was used initially for activation of the polymeric surface, thereby enhancing surface and adhesion properties. Subse-quently, preparation of porous microstructures was achieved by electrospinning technique using polydimethylsiloxane (PDMS) in combination with polyamide (PA). Finally, natural black seed oil (BSO) infiltrated the produced fiber mats acting as a lubricating layer. The optimized fiber mats' production was achieved using PDMS/PA mixture at ratio 1:1:20 (g/g/mL) using isopropyl alcohol as solvent. The surface properties of produced slippery surfaces were analyzed by various microscopic and optics techniques to obtain information about wettability, sliding behavior and surface morphology/topography. The modified PE and PU substrates demonstrated slippery behavior of an impinged water droplet at a small tilting angle. Moreover, the antimicrobial effects of the produced SLIPs using black seed oil were proven against Gram-positive Staphylococcus aureus (S. au-reus) and Gram-negative Escherichia coli (E. coli). 2021 by the authors. Licensee MDPI, Basel, Switzerland. |
Sponsor | This publication was made possible by Award JSREP07-022-3-010 from the Qatar National Research Fund (a member of The Qatar Foundation). This publication was supported by the Qatar University Collaborative grant number QUCG-CAM-20/21-3. P.H., M.L. and D.V. acknowledge that this work was supported by the Ministry of Education, Youth and Sports of the Czech Republic DKRVO (RP/CPS/2020/001). |
Language | en |
Publisher | MDPI AG |
Subject | Antimicrobial activity Electrospinning Oil infusion Plasma treatment Slippery surface |
Type | Article |
Pagination | 18-Jan |
Issue Number | 2 |
Volume Number | 13 |
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