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المؤلفAl Moustafa, Ala-Eddin
المؤلفMfoumou, Etienne
المؤلفRoman, Dacian E.
المؤلفNerguizian, Vahe
المؤلفAlazzam, Anas
المؤلفStiharu, Ion
المؤلفYasmeen, Amber
تاريخ الإتاحة2016-11-01T09:25:37Z
تاريخ النشر2016-01-21
اسم المنشورInternational Journal of Nanomedicine
المعرّفhttps://dx.doi.org/10.2147/IJN.S96361
الاقتباسAl Moustafa A-E, Mfoumou E, Roman DE, et al. Impact of single-walled carbon nanotubes on the embryo: a brief review. International Journal of Nanomedicine. 2016;11:349-355.
الرقم المعياري الدولي للكتاب1176-9114
معرّف المصادر الموحدhttp://hdl.handle.net/10576/4946
معرّف المصادر الموحدhttps://dx.doi.org/10.2147/IJN.S96361
الملخصCarbon nanotubes (CNTs) are considered one of the most interesting materials in the 21st century due to their unique physiochemical characteristics and applicability to various industrial products and medical applications. However, in the last few years, questions have been raised regarding the potential toxicity of CNTs to humans and the environment; it is believed that the physiochemical characteristics of these materials are key determinants of CNT interaction with living cells and hence determine their toxicity in humans and other organisms as well as their embryos. Thus, several recent studies, including ours, pointed out that CNTs have cytotoxic effects on human and animal cells, which occur via the alteration of key regulator genes of cell proliferation, apoptosis, survival, cell–cell adhesion, and angiogenesis. Meanwhile, few investigations revealed that CNTs could also be harmful to the normal development of the embryo. In this review, we will discuss the toxic role of single-walled CNTs in the embryo, which was recently explored by several groups including ours.
راعي المشروعthe Canadian Institutes for Health Research, the Cancer Research Society Inc. of Canada, the National Colorectal Cancer Campaign, the Fonds de la Recherche en Santé du Québec (FRSQ-Réseau du Cancer), and by the College of Medicine at Qatar University.
اللغةen
الناشرDove Press
الموضوعsingle-walled carbon nanotubes
embryo
toxicity
العنوانImpact of single-walled carbon nanotubes on the embryo: a brief review
النوعArticle
الصفحات349-355
رقم المجلد11
ESSN1178-2013
dc.accessType Open Access


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