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AuthorMahmoud, Elhassan
AuthorElsayed, Abdalla Moustafa
AuthorKaleem, Muhammad Zain
AuthorAlkorbi, Hamad A.
AuthorElshoeibi, Amgad M.
AuthorChivese, Tawanda
AuthorZughaier, Susu M.
Available date2024-03-13T10:50:38Z
Publication Date2024-01-01
Publication NameInternational Journal of Environmental Health Research
Identifierhttp://dx.doi.org/10.1080/09603123.2023.2299216
CitationMahmoud, E., Elsayed, A. M., Kaleem, M. Z., Alkorbi, H. A., Elshoeibi, A. M., Chivese, T., & Zughaier, S. M. (2024). Impact of phthalate metabolites on vitamin D levels and subclinical inflammation: national health and nutrition examination survey, 2013–2018. International Journal of Environmental Health Research, 1-11.‏
ISSN09603123
URIhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85181440836&origin=inward
URIhttp://hdl.handle.net/10576/53029
AbstractThis study explores the association between phthalates and total vitamin D levels and the link between phthalates exposure and subclinical inflammation using monocyte percentage to high-density lipoprotein cholesterol ratio (MHR), utilizing three National Health and Nutrition Examination Survey (NHANES) survey cycles 2013-2018. This study is cross-sectional, utilizing one-time urine samples from randomly selected NHANES participants to assess phthalate metabolites. An inverse association between vitamin D and all Di(2-ethylhexyl) phthalate (DEHP) metabolites was found. The molar sum of DEHP metabolites was inversely associated with vitamin D (β −2.329; 95% CI −3.937,−0.720). An inverse association was observed between monocarboxynonyl phthalate and vitamin D (β −0.0278; 95% CI −0.0527,−0.00298). A similar relationship was found between monocarboxyoctyl phthalate and vitamin D (β −0.0160; 95% CI −0.0242,−0.00775). There was no association between phthalate metabolites and MHR. Stratified analysis showed that the association between phthalate metabolites and MHR may vary according to vitamin D status.
Languageen
PublisherTaylor and Francis Ltd.
Subject25(OH)D
MHR
phthalates
plasticizers
vitamin D
TitleImpact of phthalate metabolites on vitamin D levels and subclinical inflammation: national health and nutrition examination survey, 2013–2018
TypeArticle
Pagination1-11
dc.accessType Abstract Only


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