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AuthorDarwish, Nour M.
AuthorAl-Hail, Mooza Kh
AuthorMohamed, Youssef
AuthorAl Saady, Rafif
AuthorMohsen, Sara
AuthorZar, Amna
AuthorAl-Mansoori, Layla
AuthorPedersen, Shona
Available date2024-03-14T08:44:33Z
Publication Date2023-11-24
Publication NameCancers
Identifierhttp://dx.doi.org/10.3390/cancers15235565
CitationDarwish, N. M., Al-Hail, M. K., Mohamed, Y., Al Saady, R., Mohsen, S., Zar, A., ... & Pedersen, S. (2023). The Role of Apolipoproteins in the Commonest Cancers: A Review. Cancers, 15(23), 5565.
ISSN2072-6694
URIhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85179184043&origin=inward
URIhttp://hdl.handle.net/10576/53065
AbstractApolipoproteins (APOs) are vital structural components of plasma lipoproteins that are involved in lipid metabolism and transport. Recent studies have reported an association between apolipoprotein dysregulation and the onset of a variety of human cancers; however, the role of certain APOs in cancer development remains unknown. Based on recent work, we hypothesize that APOs might be involved in the onset of cancer, with a focus on the most common cancers, including breast, lung, gynecological, colorectal, thyroid, gastric, pancreatic, hepatic, and prostate cancers. This review will focus on the evidence supporting this hypothesis, the mechanisms linking APOs to the onset of cancer, and the potential clinical relevance of its various inhibitors.
SponsorThis work was funded by QU health cluster.
Languageen
PublisherMultidisciplinary Digital Publishing Institute (MDPI)
Subjectapolipoproteins
carcinogenesis
gene expression
therapeutics
TitleThe Role of Apolipoproteins in the Commonest Cancers: A Review
TypeArticle
Issue Number23
Volume Number15
ESSN2072-6694
dc.accessType Open Access


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