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AuthorMokhena, T.C.
AuthorLuyt, A.S.
Available date2017-03-01T11:08:30Z
Publication Date2017-06-01
Publication NameCarbohydrate Polymers
Identifierhttp://dx.doi.org/10.1016/j.carbpol.2017.02.068
ISSN01448617
URIhttp://www.sciencedirect.com/science/article/pii/S0144861717301984
URIhttp://hdl.handle.net/10576/5334
AbstractAbstract Silver nanoparticles are amongst the most valuable nanoparticles with interesting properties, such as a non-toxic nature and high antibacterial efficiency, making them applicable for tissue scaffold, protective clothing and wound dressing. In this study, silver nanoparticles (AgNPs) have been synthesized using chitosan as reducing and stabilizing agent. The formation of silver nanoparticles was confirmed by UV-vis, and the TEM showed that different shapes were obtained depending on the heating duration. The chitosan/AgNPs was coated onto an electrospun alginate membrane to produce stable polyelectrolyte complex (PEC) nanofibre composites with high antibacterial efficiency. These composites were characterized by scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD). AgNPs were successfully impregnated into the PEC nanofibre composite, while there was complexation between the electrospun alginate and the chitosan/AgNPs composite. PEC demonstrated a good antibacterial activity against both gram negative and gram positive bacteria with acceptable water vapour transmission within the range required for the treatment of injuries or wounds.
Languageen
PublisherElsevier
SubjectChitosan
SubjectSilver nanoparticles
SubjectElectrospun alginate
SubjectPolyelectrolyte complex
SubjectAntibacterial activity
TitleElectrospun alginate nanofibres impregnated with silver nanoparticles: Preparation, morphology and antibacterial properties
TypeArticle
Pagination304-312
Volume Number165


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