Sex-based differences in severity and mortality in COVID-19
Date
2021Author
Alwani, MustafaYassin, Aksam
Al-Zoubi, Raed M.
Aboumarzouk, Omar M.
Nettleship, Joanne
Kelly, Daniel
AL-Qudimat, Ahmad R.
Shabsigh, Ridwan
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Show full item recordAbstract
The current coronavirus disease (COVID-19) pandemic caused by novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has a male bias in severity and mortality. This is consistent with previous coronavirus pandemics such as SARS-CoV and MERS-CoV, and viral infections in general. Here, we discuss the sex-disaggregated epidemiological data for COVID-19 and highlight underlying differences that may explain the sexual dimorphism to help inform risk stratification strategies and therapeutic options.
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