Iron shuttle chelation therapy enhances to reduce misplaced iron on secondary iron overloaded adult zebrafish
المؤلف | Mustafa, Ibrahim |
المؤلف | Khalaf, Israa Magdi Nassef |
المؤلف | Younes, Salma Nagy |
المؤلف | Saleem, Rola |
المؤلف | Nasrellah, Gheyath |
تاريخ الإتاحة | 2017-11-14T11:11:16Z |
تاريخ النشر | 2017-03-16 |
اسم المنشور | 7th Emirates Hematology Conference Proceedings 2016 |
الاقتباس | Mustafa, I., Khalaf, I. M. N., Younes, S. N., Saleem, R. and Nasrellah, G.(2016)."Iron shuttle chelation therapy enhances to reduce misplaced iron on secondary iron overloaded adult zebrafish" 7th Emirates Hematology Conference Proceedings 2016, PP26 . |
الملخص | Thalassemia is the most common genetically inherited blood disorder in the world arises from defect in hemoglobin production, results in ineffective erythropoiesis and the rapid destruction of RBC in the periphery that leads to severe anemia. While transfusion therapy corrects the anemia, it gives rise to secondary iron overload. The current available iron chelation therapy has issues with toxicity and compliance. Our hypothesis is iron shuttle chelation therapy using combined iron chelators may have better effect in iron loaded adult zebrafish. |
راعي المشروع | Qatar University |
اللغة | en |
الموضوع | iron overload Thalassaemia zebrafish |
النوع | Conference Paper |
الصفحات | PP26 |
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