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AuthorFarah, Siddiqui
AuthorKalache, Karim
AuthorAhmed, Badreledeen
AuthorKonje, Justin C.
Available date2024-11-03T07:58:11Z
Publication Date2024-03-21
Publication NameBest Practice & Research Clinical Obstetrics & Gynaecology
Identifierhttp://dx.doi.org/10.1016/j.bpobgyn.2024.102470
CitationSiddiqui, F., Kalache, K., Ahmed, B., & Konje, J. C. (2024). Challenges of prenatal diagnosis in obese pregnant women. Best Practice & Research Clinical Obstetrics & Gynaecology, 102470.
ISSN1521-6934
URIhttps://www.sciencedirect.com/science/article/pii/S1521693424000166
URIhttp://hdl.handle.net/10576/60795
AbstractObesity rates are increasing world-wide with most of the increase in women of the reproductive age group. While recognised as an important contributor to non-communicable diseases, pregnant women with obesity are particularly at risk of not only maternal and pregnant complications but also have an increased risk of congenital malformations. Furthermore, pregnant obese women are more likely to be older and therefore at a greater risk of aneuploidy. Prenatal diagnosis in these women especially those who are morbidly obese is challenging due not only to their weight but the implications of the increase adiposity on biochemical markers of aneuploidy. In this review we discuss the current challenges in providing prenatal diagnosis for these women including those related to the ergonomics of ultrasound and those inherent in them because of their obesity. Appropriate counselling for these women should include the lower sensitivity of the tests, the difficulties in performing some of the procedures (imaging and invasive testing) as well as the increased risk of structural abnormalities related to their obesity.
Languageen
PublisherElsevier
SubjectObesity
Prenatal diagnosis
Biochemical markers
Non-invasive testing
Non-invasive diagnosis
Free fetal DNA
Amniocentesis
Chorionic villus sampling
TitleChallenges of prenatal diagnosis in obese pregnant women
TypeArticle
Volume Number95
ESSN1532-1932
dc.accessType Full Text


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