Browsing Biomedical Research Center by Author "Alhussain, Hashim"
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Detection of SARS-CoV-2 RNA by direct RT-qPCR on nasopharyngeal specimens without extraction of viral RNA.
Hasan, Mohammad Rubayet; Mirza, Faheem; Al-Hail, Hamad; Sundararaju, Sathyavathi; Xaba, Thabisile; Iqbal, Muhammad; Alhussain, Hashim; Yassine, Hadi Mohamad; Perez-Lopez, Andres; Tang, Patrick... more authors ... less authors ( Public Library of Science , 2020 , Article)To circumvent the limited availability of RNA extraction reagents, we aimed to develop a protocol for direct RT-qPCR to detect SARS-CoV-2 in nasopharyngeal swabs without RNA extraction. Nasopharyngeal specimens positive ... -
E-Cigarette Liquid Provokes Significant Embryotoxicity and Inhibits Angiogenesis.
Ashour, Anas; Alhussain, Hashim; Rashid, Umar Bin; Abughazzah, Labiba; Gupta, Ishita; Malki, Ahmed; Vranic, Semir; Al Moustafa, Ala-Eddin... more authors ... less authors ( MDPI , 2020 , Article)E-cigarette smoking (ECS) is a new method of tobacco smoking that is gaining popularity as it is thought to be a "healthy method" of tobacco consumption. The adverse outcomes of ECS on the respiratory and cardiovascular ... -
A novel in ovo model to study cancer metastasis using chicken embryos and GFP expressing cancer cells.
Augustine, Robin; Alhussain, Hashim; Hasan, Anwarul; Badie Ahmed, Mohamed; C Yalcin, Huseyin; Al Moustafa, Ala-Eddin... more authors ... less authors ( Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina , 2019 , Article)Cancer metastasis is the leading cause of cancer-related mortality worldwide. To date, several in vitro methodologies have been developed to understand the mechanisms of cancer metastasis and to screen various therapeutic ... -
Prognostic tools and candidate drugs based on plasma proteomics of patients with severe COVID-19 complications
Al-Nesf, Maryam A. Y.; Abdesselem, Houari B.; Bensmail, Ilham; Ibrahim, Shahd; Saeed, Walaa A. H.; Mohammed, Sara S. I.; Razok, Almurtada; Alhussain, Hashim; Aly, Reham M. A.; Al Maslamani, Muna; Ouararhni, Khalid; Khatib, Mohamad Y.; Hssain, Ali Ait; Omrani, Ali S.; Al-Kaabi, Saad; Al Khal, Abdullatif; Al-Thani, Asmaa A.; Samsam, Waseem; Farooq, Abdulaziz; Al-Suwaidi, Jassim; Al-Maadheed, Mohammed; Al-Siddiqi, Heba H.; Butler, Alexandra E.; Decock, Julie V.; Mohamed-Ali, Vidya; Al-Ejeh, Fares... more authors ... less authors ( Nature Research , 2022 , Article)COVID-19 complications still present a huge burden on healthcare systems and warrant predictive risk models to triage patients and inform early intervention. Here, we profile 893 plasma proteins from 50 severe and 50 ... -
Risk Management Assessments and Recommendations Among Students, Staffs, and Health Care Workers in Educational Biomedical Laboratories.
Rizk, Nasser M; AlShammari, Wasaif; Alhussain, Hashim (2021 , Article)Safety in laboratories is one of the most crucial topics for all educational institutes. All-hazards need to be identified, evaluated, and controlled whenever possible, following the risk management (RM) process. This study ... -
Seroprevalence of camel brucellosis in Qatar
Alhussain, Hashim; Zughaier, Susu M.; Gawish, Ahmed; Mahmoud, Mahmoud H.; Yassine, Hadi M.; Al Thani, Asmaa; Obied, Tahra El; Al-Zeyara, Abdulaziz M.; Eltai, Nahla O.... more authors ... less authors ( Springer , 2022 , Article)Brucellosis is a significant zoonotic disease and one of the most common neglected diseases worldwide. It can infect a wide range of domestic and wild animal species. Infected animals are usually culled, causing substantial ... -
The Spectrum of Antibiotic Prescribing During COVID-19 Pandemic: A Systematic Literature Review
Al-Hadidi, Sara H.; Alhussain, Hashim; Abdel Hadi, Hamad; Johar, Alreem; Yassine, Hadi M.; Al Thani, Asmaa A.; Eltai, Nahla O.... more authors ... less authors ( Mary Ann Liebert , 2021 , Article Review)Objectives: Over the last decades, there has been a significant increase in antimicrobial prescribing and consumption associated with the development of patients’ adverse events and antimicrobial resistance (AMR) to the ... -
Substantial cell apoptosis provoked by naked PAMAM dendrimers in HER2-positive human breast cancer via JNK and ERK1/ERK2 signalling pathways
Hadeel, Kheraldine; Gupta, Ishita; Alhussain, Hashim; Jabeen, Aayesha; Cyprian, Farhan S.; Akhtar, Saghir; Al Moustafa, Ala-Eddin; Rachid, Ousama... more authors ... less authors ( Elsevier , 2021 , Article)HER2-positive breast cancer is one of its most challenging subtypes, forming around 15–25% of the total cases. It is characterized by aggressive behavior and treatment resistance. On the other hand, poly (amidoamine) (PAMAM) ... -
The Spectrum of Antibiotic Prescribing during COVID-19 Pandemic: A Systematic Literature Review
Al-Hadidi, Sara H.; Alhussain, Hashim; Abdel Hadi, Hamad; Johar, Alreem; Yassine, Hadi M.; Al Thani, Asmaa A.; Eltai, Nahla O.... more authors ... less authors ( Mary Ann Liebert Inc. , 2021 , Article Review)Objectives: Over the last decades, there has been a significant increase in antimicrobial prescribing and consumption associated with the development of patients' adverse events and antimicrobial resistance (AMR) to the ... -
Urine tests for diagnosis of infectious diseases and antibiotic –resistant pathogens
Eltai, Nahla; Alhussain, Hashim; Al-Thani, Asma; Yassine, Hadi; Doiphode, Sanjay ( IntechOpen , 2019 , Book chapter)The relation between disease and urine was recognized by physicians since the earliest civilization BC. Urine is considered an ideal diagnostic specimen for its noninvasive and easy method of collection. Urinalysis encompasses ...