Browsing Biomedical Research Center by Publisher "Elsevier"
Now showing items 1-20 of 107
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3D hydrogel/ bioactive glass scaffolds in bone tissue engineering: Status and future opportunities
( Elsevier , 2023 , Article Review)Repairing significant bone defects remains a critical challenge, raising the clinical demand to design novel bone biomaterials that incorporate osteogenic and angiogenic properties to support the regeneration of vascularized ... -
A calcium peroxide incorporated oxygen releasing chitosan-PVA patch for Diabetic wound healing
( Elsevier , 2023 , Article)Impaired wound healing is a major healthcare problem in patients with diabetes often resulting in gangrene, microbial infection and amputation of affected limb. The delay or absence in healing process arises from several ... -
Activation Dynamics and Immunoglobulin Evolution of Pre-existing and Newly Generated Human Memory B cell Responses to Influenza Hemagglutinin.
( Elsevier , 2019 , Article)Vaccine-induced memory B cell responses to evolving viruses like influenza A involve activation of pre-existing immunity and generation of new responses. To define the contribution of these two types of responses, we ... -
Advanced blood flow assessment in Zebrafish via experimental digital particle image velocimetry and computational fluid dynamics modeling
( Elsevier , 2020 , Article)Over the past few decades, Zebrafish has become a widely used vertebrate model for cardiovascular research. Easy genetic manipulation, low cost, high fecundity, embryonic transparency, and ability to survive in the early ... -
Air-jet spun tissue engineering scaffolds incorporated with diamond nanosheets with improved mechanical strength and biocompatibility
( Elsevier , 2023 , Article)The development of highly porous cell supportive polymeric scaffolds with sufficient mechanical strength has always been a challenging task in tissue engineering. The widely used nanofiber fabrication methods like ... -
Assessment of calcified aortic valve leaflet deformations and blood flow dynamics using fluid-structure interaction modeling
( Elsevier , 2017 , Article)Aortic valve diseases are among the most common cardiovascular defects. Since a non-functioning valve results in disturbed blood flow conditions, the diagnosis of such defects is based on identification of stenosis via ... -
Assessment of calcified aortic valve leaflet deformations and blood flow dynamics using fluid-structure interaction modeling
( Elsevier , 2017 , Article)Aortic valve diseases are among the most common cardiovascular defects. Since a non-functioning valve results in disturbed blood flow conditions, the diagnosis of such defects is based on identification of stenosis via ... -
Attitudes and beliefs regarding the use of herbs and supplementary medications with COVID-19: A systematic review
( Elsevier , 2022 , Article)Background and aimThere is growing interest in using herbs and supplementary medications to treat and/or prevent COVID-19, evidenced by multiple reports exploring their effectiveness and safety. From a health psychology ... -
Bio-vehicles of cytotoxic drugs for delivery to tumor specific targets for cancer precision therapy
( Elsevier , 2021 , Article Review)Abnormal structural and molecular changes in malignant tissues were thoroughly investigated and utilized to target tumor cells, hence rescuing normal healthy tissues and lowering the unwanted side effects as non-specific ... -
Bioactive scaffold (sodium alginate)-g-(nHAp@SiO2@GO) for bone tissue engineering
( Elsevier , 2022 , Article)Globally, people suffering from bone disorders are steadily increasing and bone tissue engineering is an advanced approach to treating fractured and defected bone tissues. In this study, we have prepared polymeric nanocomposite ... -
Biocompatibility and toxicity of novel iron chelator Starch-Deferoxamine (S-DFO) compared to zinc oxide nanoparticles to zebrafish embryo: An oxidative stress based apoptosis, physicochemical and neurological study profile.
( Elsevier , 2019 , Article)Clinically approved iron chelators are effective in decreasing significant transfusional iron accumulation. Starch-Deferoxamine (S-DFO), a novel high molecular weight iron chelator, was produced to increase binding capacity ... -
BNT162b2 antigen dose and SARS-CoV-2 omicron infection in adolescents
( Elsevier , 2023 , Other)COVID-19 vaccine antigen dose might affect protection against SARS-CoV-2 infection,1, 2 but direct evidence to quantify this effect is absent. We conducted a matched, retrospective, cohort study using a regression ... -
Burden and disease pathogenesis of influenza and other respiratory viruses in diabetic patients
( Elsevier , 2022 , Article Review)Over the past two decades, diabetes mellitus (DM) has been receiving increasing attention among autoimmune diseases. The prevalence of type 1 and type 2 diabetes has increased rapidly and has become one of the leading ... -
Calreticulin regulates Src kinase in osteogenic differentiation from embryonic stem cells
( Elsevier , 2020 , Article)Calreticulin, the major Ca2+ buffer of the endoplasmic reticulum plays an important role in the choice of fate by embryonic stem cells. Using the embryoid body method of organogenesis, we showed impaired osteogenesis in ... -
Cardiac function and blood flow hemodynamics assessment of zebrafish (Danio rerio) using high-speed video microscopy
( Elsevier , 2020 , Article)BackgroundIn the last few decades, zebrafish (Danio rerio) were introduced as a model organism to investigate human diseases including cardiovascular and neuronal disorders. In most zebrafish investigations, cardiac function ... -
Chitin-based nanomaterials
( Elsevier , 2021 , Book chapter)Chitin- and chitosan-based materials have been increasingly used in various scientific advancements specifically in the field of nanotechnology for their therapeutic potential. They are biopolymeric polysaccharides with ... -
Chitosan gold nanoparticles for detection of amplified nucleic acids isolated from sputum
( Elsevier , 2017 , Article)A platform for nucleic acid detection employing chitosan and chitosan coated gold nanoparticles (AuNPs) was developed. Mycobacterium tuberculosis (MTB) was used as a model target. MTB DNA was extracted from sputum using ... -
Comparable antibody levels in heterologous and homologous mRNA COVID-19 vaccination, with superior neutralizing and IgA antibody responses in mRNA homologous boosting
( Elsevier , 2024 , Article)BackgroundPriming with two doses of AZD1222 (Oxford-AstraZeneca; ChAd) followed by a third mRNA vaccine boosting is considered in several countries, yet comparisons between heterologous and homologous booster efficacy ... -
Comparative analysis of within-host diversity among vaccinated COVID-19 patients infected with different SARS-CoV-2 variants
( Elsevier , 2022 , Article)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a rapidly evolving RNA virus that mutates within hosts and exists as viral quasispecies. Here, we evaluated the within-host diversity among vaccinated and ... -
Comparing metabolic profiles between female endurance athletes and non-athletes reveals differences in androgen and corticosteroid levels
( Elsevier , 2022 , Article)Endurance training is associated with physiological changes in elite athletes, but little is known about female-specific effects of endurance training. Despite the significant rise in female sports participation, findings ...