Browsing Biomedical Research Center by Title
Now showing items 390-407 of 407
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Urine tests for diagnosis of infectious diseases and antibiotic –resistant pathogens
( IntechOpen , 2019 , Book chapter)The relation between disease and urine was recognized by physicians since the earliest civilization BC. Urine is considered an ideal diagnostic specimen for its noninvasive and easy method of collection. Urinalysis encompasses ... -
Use of Hemagglutinin Stem Probes Demonstrate Prevalence of Broadly Reactive Group 1 Influenza Antibodies in Human Sera.
( Nature Publishing Group , 2018 , Article)A better understanding of the seroprevalence and specificity of influenza HA stem-directed broadly neutralizing antibodies (bNAbs) in the human population could significantly inform influenza vaccine design efforts. Here, ... -
Using Zebrafish for Investigating the Molecular Mechanisms of Drug-Induced Cardiotoxicity
( Hindawi Publishing Corporation , 2018 , Article)Over the last decade, the zebrafish (Danio rerio) has emerged as amodel organismfor cardiovascular research.Zebrafish have several advantages over mammalian models. For instance, the experimental cost of using zebrafish ... -
Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses
( Elsevier Inc. , 2016 , Article)Antibodies capable of neutralizing divergent influenza A viruses could form the basis of a universal vaccine. Here, from subjects enrolled in an H5N1 DNA/MIV-prime-boost influenza vaccine trial, we sorted hemagglutinin ... -
VEGF-121 plasma level as biomarker for response to anti-angiogenetic therapy in recurrent glioblastoma.
( BioMed Central , 2018 , Article)Vascular endothelial growth factor (VEGF) isoforms, particularly the diffusible VEGF-121, could play a major role in the response of recurrent glioblastoma (GB) to anti-angiogenetic treatment with bevacizumab. We hypothesized ... -
Viral-Induced Enhanced Disease Illness
( Frontiers Media , 2018 , Article)Understanding immune responses to viral infections is crucial to progress in the quest for effective infection prevention and control. The host immunity involves various mechanisms to combat viral infections. Under certain ... -
Viruses and Autoimmunity: A Review on the Potential Interaction and Molecular Mechanisms.
( MDPI , 2019 , Article)For a long time, viruses have been shown to modify the clinical picture of several autoimmune diseases, including type 1 diabetes (T1D), systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), Sjögren's syndrome ... -
Water-pipe smoking and serum testosterone levels in adult males in Qatar.
( European Publishing , 2019 , Article)Water-pipe (WP) smoking is the most common method of tobacco consumption in the Middle-East and is rapidly spreading on a global scale. Although, water-pipe smoking is linked to various diseases, such as emphysema and ... -
Water-Pipe Smoking Exposure Deregulates a Set of Genes Associated with Human Head and Neck Cancer Development and Prognosis.
( MDPI , 2020 , Article)Water-pipe smoking (WPS) is becoming the most popular form of tobacco use among the youth, especially in the Middle East, replacing cigarettes rapidly and becoming a major risk of tobacco addiction worldwide. Smoke from ... -
Water-pipe smoking promotes epithelial-mesenchymal transition and invasion of human breast cancer cells via ERK1/ERK2 pathways.
( BioMed Central Ltd. , 2018 , Article)With the increasing popularity of water-pipe smoking (WPS), it is critical to comprehend how WPS may affect women's health. The main goal of this study is to identify the potential outcome of WPS on human breast cancer ... -
White Button Mushroom, Agaricus bisporus (Agaricomycetes), and a Probiotics Mixture Supplementation Correct Dyslipidemia without Influencing the Colon Microbiome Profile in Hypercholesterolemic Rats
( Begell House , 2020 , Article)Consumption of foods rich in dietary fiber has attracted considerable attention for lowering blood cholesterol and triglycerides through attenuation of gut microbiome. Diets rich in fiber may provide substrates for microbes ... -
Whole-Genome Sequencing for Molecular Characterization of Carbapenem-Resistant Enterobacteriaceae Causing Lower Urinary Tract Infection among Pediatric Patients
( MDPI , 2021 , Article)Antibiotic resistance is a growing public health problem globally, incurring health and cost burdens. The occurrence of antibiotic-resistant bacterial infections has increased significantly over the years. Gram-negative ... -
Within-Host Diversity of SARS-CoV-2 in COVID-19 Patients With Variable Disease Severities.
( Frontiers Media , 2020 , Article)The ongoing pandemic of SARS-COV-2 has already infected more than eight million people worldwide. The majority of COVID-19 patients either are asymptomatic or have mild symptoms. Yet, about 15% of the cases experience ... -
Xeno-free trans-differentiation of adipose tissue-derived mesenchymal stem cells into glial and neuronal cells.
( e-Century Publishing , 2019 , Article)Mesenchymal stem cells (MSCs) are undifferentiated cells that have the ability of self-renewal and trans-differentiation into other cell types. They hold out hope for finding a cure for many diseases. Nevertheless, there ... -
A YEAST TWO-HYBRID SCREEN REVEALS A STRONG INTERACTION BETWEEN THE LEGIONELLA CHAPERONIN Hsp60 AND THE HOST CELL SMALL HEAT SHOCK PROTEIN Hsp10
( Akadémiai Kiadó , 2015 , Article)L. pneumophila is an intracellular bacterium that replicates inside a membrane- bound vacuole called Legionella-containing vacuole (LCV), where it plentifully liberates its HtpB chaperonin. From LCV, HtpB reaches the ... -
Yttrium oxide nanoparticle loaded scaffolds with enhanced cell adhesion and vascularization for tissue engineering applications
( Elsevier Ltd , 2019 , Article)In situ tissue engineering is emerging as a novel approach in tissue engineering to repair damaged tissues by boosting the natural ability of the body to heal itself. This can be achieved by providing suitable signals and ... -
Zebrafish as a Model for Anticancer Nanomedicine Studies.
( MDPI , 2021 , Article Review)Nanomedicine is a new approach to fight against cancer by the development of anticancer nanoparticles (NPs) that are of high sensitivity, specificity, and targeting ability to detect cancer cells, such as the ability of ... -
Zebrafish larvae as a model to demonstrate secondary iron overload.
( Wiley , 2018 , Article)Thalassemia is the most common genetically inherited blood disorder arising from a defect in hemoglobin production, resulting in ineffective erythropoiesis and severe hemolytic anemia. While transfusion therapy corrects ...
