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Molecular and Biological Mechanisms Underlying Gender Differences in COVID-19 Severity and Mortality
(
Frontiers Media
, 2021 , Article)
Globally, over two million people have perished due to the recent pandemic caused by SARS-CoV-2. The available epidemiological global data for SARS-CoV-2 portrays a higher rate of severity and mortality in males. Analyzing ...
Advancing male age differentially alters levels and localization patterns of PLCzeta in sperm and testes from different mouse strains
(
Medknow Publications
, 2021 , Article)
Sperm-specific phospholipase C zeta (PLC) initiates intracellular calcium (Ca2+) transients which drive a series of concurrent events collectively termed oocyte activation. Numerous investigations have linked abrogation ...
Dysbiosis of the Salivary Microbiome is Associated with Hypertension and Correlated with Metabolic Syndrome Biomarkers
(
Dovepress
, 2021 , Article)
Background: Hypertension (HT) is an idiopathic disease with severe complications and a high incidence of global mortality. Although the disease shares characteristic features with diabetes and obesity, the complex interplay ...
Synthesis and Optimization of a Highly Stable and Efficient BN/TiO2 Nanocomposite for Phenol Degradation: A Photocatalytic, Mechanistic and Environmental Impact Study
(
Wiley
, 2021 , Article)
Different BN/TiO2 nanocomposites were prepared hydrothermally, and their ratio was optimized to get the best photocatalytic performance towards phenol degradation. They were characterized by x-ray photoelectron spectroscopy, ...
SARS-CoV-2 involvement in central nervous system tissue damage
(
Wolters Kluwer
, 2022 , Article Review)
As the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread globally, it became evident that the SARS-CoV-2 virus infects multiple organs including the brain. Several clinical studies revealed ...
Assessment of calcified aortic valve leaflet deformations and blood flow dynamics using fluid-structure interaction modeling
(
Elsevier
, 2017 , Article)
Aortic valve diseases are among the most common cardiovascular defects. Since a non-functioning valve results in disturbed blood flow conditions, the diagnosis of such defects is based on identification of stenosis via ...
Oxidative Stress-Induced Endothelial Dysfunction in Cardiovascular Diseases
(
IMR Press
, 2022 , Article Review)
Cardiovascular disease (CVD) is a major cause of mortality worldwide. A better understanding of the mechanisms underlying CVD is key for better management or prevention. Oxidative stress has been strongly implicated in the ...
Nanomedicine as a Potential Tool against Monkeypox.
(
MDPI
, 2023 , Article Review)
Human monkeypox is a rare viral zoonosis that was first identified in 1970; since then, this infectious disease has been marked as endemic in central and western Africa. The disease has always been considered rare and ...
Blood Flow Disturbance and Morphological Alterations Following the Right Atrial Ligation in the Chick Embryo.
(
Frontiers Media
, 2022 , Article)
Collectively known as congenital heart defects (CHDs), cardiac abnormalities at birth are the most common forms of neonatal defects. Being principally responsible for the heart's pumping power, ventricles are particularly ...
In Vitro and In Vivo Validation of GATA-3 Suppression for Induction of Adipogenesis and Improving Insulin Sensitivity
(
MDPI
, 2022 , Article)
Impaired adipogenesis is associated with the development of insulin resistance and an increased risk of type 2 diabetes (T2D). GATA Binding Protein 3 (GATA3) is implicated in impaired adipogenesis and the onset of insulin ...