Biomedical Research Center: Recent submissions
Now showing items 201-220 of 772
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Will influenza A(H3N8) cause a major public health threat?
( Elsevier , 2022 , Article)The diversity of zoonotic influenza viruses and their ability to cross the species barrier has always been alarming and requires continuous surveillance in both human and animal populations. Avian A(H3N8) influenza viruses ... -
Assessment of calcified aortic valve leaflet deformations and blood flow dynamics using fluid-structure interaction modeling
( Elsevier , 2017 , Article)Aortic valve diseases are among the most common cardiovascular defects. Since a non-functioning valve results in disturbed blood flow conditions, the diagnosis of such defects is based on identification of stenosis via ... -
A single tube system for the detection of Mycobacterium tuberculosis DNA using gold nanoparticles based FRET assay
( Elsevier , 2017 , Article)The global combat against MTB is limited by challenges in accurate affordable detection. In this study, a rapid, affordable, single tube system for detection of unamplified MTB16s rDNA was developed. Utilizing a AuNP based ... -
Enteric pathogens modulate metabolic homeostasis in the Drosophila melanogaster host
( Elsevier , 2022 , Article)On quotidian basis, living beings work out an armistice with their microbial flora and a scuffle with invading pathogens to maintain a normal state of health. Although producing virulence factors and escaping the host's ... -
Molecular epidemiology, genetic diversity, and vaccine availability of viral acute gastroenteritis in the middle East and North Africa (MENA) region
( Elsevier , 2022 , Article)Acute gastroenteritis is the cause of considerable mortality and morbidity worldwide, particularly among children under five years in underdeveloped countries. Most acute gastroenteritis (AGE) cases are attributed to viral ... -
Comparative analysis of within-host diversity among vaccinated COVID-19 patients infected with different SARS-CoV-2 variants
( Elsevier , 2022 , Article)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a rapidly evolving RNA virus that mutates within hosts and exists as viral quasispecies. Here, we evaluated the within-host diversity among vaccinated and ... -
Intake of Caffeine Containing Sugar Diet Remodels Gut Microbiota and Perturbs Drosophila melanogaster Immunity and Lifespan
( Elsevier , 2023 , Article)The diet-microbiome-immunity axis is one among the many arms that draw up the “we are what we intake” proclamation. As such, studies on the effect of food and beverage intake on the gut environment and microbiome and on ... -
Single-Cell RNA Sequencing with Spatial Transcriptomics of Cancer Tissues
( MDPI , 2022 , Article Review)Single-cell RNA sequencing (RNA-seq) techniques can perform analysis of transcriptome at the single-cell level and possess an unprecedented potential for exploring signatures involved in tumor development and progression. ... -
The stereological, immunohistological, and gene expression studies in an infected ischemic wound in diabetic rats treated by human adipose-derived stem cells and photobiomodulation
( Institute for Ionics , 2023 , Article)We investigated the impacts of photobiomodulation (PBM) and human allogeneic adipose-derived stem cells (ha-ADS) together and or alone applications on the stereological parameters, immunohistochemical characterizing of M1 ... -
Multifunctional Bioactive Scaffolds from ARX- g-(Zn@rGO)-HAp for Bone Tissue Engineering: In Vitro Antibacterial, Antitumor, and Biocompatibility Evaluations
( American Chemical Society , 2022 , Article)Advanced biomaterials are required with enhanced antibacterial and anticancer activities to obtain desirable biocompatibility during and after scaffold implantation in tissue engineering. Here, we report the development ... -
Zinc oxide loaded chitosan-elastin-sodium alginate nanocomposite gel using freeze gelation for enhanced adipose stem cell proliferation and antibacterial properties
( Elsevier , 2023 , Article)Hydrogels have been the material of choice for regenerative medicine applications due to their biocompatibility that can facilitate cellular attachment and proliferation. The present study aimed at constructing a porous ... -
Bioactive scaffold (sodium alginate)-g-(nHAp@SiO2@GO) for bone tissue engineering
( Elsevier , 2022 , Article)Globally, people suffering from bone disorders are steadily increasing and bone tissue engineering is an advanced approach to treating fractured and defected bone tissues. In this study, we have prepared polymeric nanocomposite ... -
Air-jet spun tissue engineering scaffolds incorporated with diamond nanosheets with improved mechanical strength and biocompatibility
( Elsevier , 2023 , Article)The development of highly porous cell supportive polymeric scaffolds with sufficient mechanical strength has always been a challenging task in tissue engineering. The widely used nanofiber fabrication methods like ... -
Role of Graphene Oxide in Bacterial Cellulose−Gelatin Hydrogels for Wound Dressing Applications
( American Chemical Society , 2022 , Article)Biopolymer-based hydrogels have several advantages, including robust mechanical, high biocompatibility, and excellent properties. These hydrogels can be ideal wound dressing materials and advantageous to repair and regenerate ... -
Corrigendum to: Reduced Graphene Oxide Incorporated GelMA Hydrogel Promotes Angiogenesis for Wound Healing Applications [Corrigendum] (Int J Nanomedicine. 2019;14:9603-9617)
( Dove Medical Press Ltd , 2022 , Article)The authors have advised that an error was made during the preparation of the wound healing scratch assay images shown in Figure 6 on page 9613. All the original data was retained and a correct image for the GrG4, Endothelial, ... -
Nano-Engineering in Traumatic Brain Injury
( Wiley , 2023 , Book chapter)Traumatic brain injury (TBI) is a leading cause of mortality and chronic disability worldwide TBI involves an initial primary phase triggered by an impactful force to the brain and a subsequent secondary pathological phase. ... -
Fetal ECG extraction from maternal ECG using deeply supervised LinkNet++ model
( Elsevier , 2023 , Article)Fetal heart monitoring and early disease detection using non-invasive fetal electrocardiograms (fECG) can help substantially to reduce infant death through improved diagnosis of Coronary Heart Disease (CHD) in the fetus. ... -
The Metabolic Switch of Physical Activity in Non-Obese Insulin Resistant Individuals.
( MDPI , 2023 , Article)Healthy non-obese insulin resistant (IR) individuals are at higher risk of metabolic syndrome. The metabolic signature of the increased risk was previously determined. Physical activity can lower the risk of insulin ... -
The retrospective study of the metabolic patterns of BCG-vaccination in type-2 diabetic individuals in COVID-19 infection
( Frontiers Media , 2023 , Article)Background: The cross-protective nature of Bacillus Calmette-Guerin (BCG) vaccine against SARS-CoV-2 virus was previously suggested, however its effect in COVID-19 patients with type 2 diabetes (T2D) and the underlying ... -
The therapeutic potential of matcha tea: A critical review on human and animal studies
( Elsevier , 2023 , Article Review)Matcha is a powdered form of Japanese green tea that has been gaining global popularity recently. Matcha tea has various health benefits, including an enhancing effect on cognitive function, cardio-metabolic health, and ...
