Biomedical Research Center: Recent submissions
Now showing items 621-640 of 808
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Qatar Biobank: A Paradigm of Translating Biobank Science into Evidence-Based Health Care Interventions
( Mary Ann Liebert , 2019 , Article)Biobank science is progressively becoming indispensable for the development of novel diagnostic tools in health care, by pairing standardized high-quality biological samples, phenotypic, and omics data required to best ... -
The Implementation of an Integrated Management System at Qatar Biobank
( Mary Ann Liebert , 2019 , Article)Qatar Biobank (QBB) is a platform that will make vital health research possible through its collection of samples and information on health and lifestyle from the local population of Qatar. The goal of QBB is to collect, ... -
Conception, Implementation, and Integration of Heterogenous Information Technology Infrastructures in the Qatar Biobank
( Mary Ann Liebert , 2019 , Article)The overall goal of the Qatar Biobank (QBB) is to collect, manage, and distribute high-quality human biospecimens with appropriate clinical and/or research annotation and associated phenotypic data, aiming to be an important ... -
Profiling the Oral Microbiome and Plasma Biochemistry of Obese Hyperglycemic Subjects in Qatar
( MDPI , 2019 , Article)The present study is designed to compare demographic characteristics, plasma biochemistry, and the oral microbiome in obese (N = 37) and lean control (N = 36) subjects enrolled at Qatar Biobank, Qatar. Plasma hormones, ... -
Metabolic signature of obesity-associated insulin resistance and type 2 diabetes.
( BMC , 2019 , Article)Obesity is associated with an increased risk of insulin resistance and type 2 diabetes mellitus (T2DM). However, some obese individuals maintain their insulin sensitivity and exhibit a lower risk of associated comorbidities. ... -
Mediators of Impaired Adipogenesis in Obesity-Associated Insulin Resistance and T2DM
( IntechOpen , 2019 , Book chapter)Obesity has become a global health issue due to its high prevalence and associated comorbidities including insulin resistance (IR) and type 2 diabetes mellitus (T2DM). Obesity is associated with the expansion of adipose ... -
Metabolic profiling of elite athletes with different cardiovascular demand
( John Wiley & Sons Ltd , 2019 , Article)Intensive exercise of elite athletes can lead to physiological alterations in the cardiovascular system in response to increased stroke volume and blood pressure, known collectively as cardiovascular demand (CD). This study ... -
Measuring influenza hemagglutinin (HA) stem-specific antibody-dependent cellular cytotoxicity (ADCC) in human sera using novel stabilized stem nanoparticle probes
( Elsevier , 2019 , Article)BackgroundGenerating vaccine that confers a complete protection is a major goal in designing a universal influenza vaccine. Currently, there is a considerable interest in the broadly neutralizing antibodies (bnAb) targeting ... -
The Current Status of Cytomegalovirus (CMV) Prevalence in the MENA region: a systematic review
( MDPI , 2019 , Article)Human cytomegalovirus (CMV) is a highly prevalent herpesvirus worldwide. According to the Centers for Disease Control and Prevention (CDC) and the World Health Organization (WHO), CMV infects people of all ages, and by ... -
Cryptosporidium spp., prevalence, molecular characterisation and socio-demographic risk factors among immigrants in Qatar.
( Public Library of Science , 2019 , Article)The World Health Organization WHO has estimated that in developed countries, up to 30% of the population may suffer from foodborne diseases each year, and that in developing countries up to 2 million deaths per annum can ... -
Co-prevalence of Epstein-Barr virus and high-risk human papillomaviruses in Syrian women with breast cancer.
( Taylor & Francis , 2016 , Article)ABSTRAT We recently performed 2 studies viewing the presence of Epstein-Barr virus (EBV) and high-risk human papillomaviruses (HPVs) types 16, 18, 31, 33 and 35 in human breast cancer in the Syrian population. Herein, we ... -
Titanium Nanorods Loaded PCL Meshes with Enhanced Blood Vessel Formation and Cell Migration for Wound Dressing Applications.
( Wiley , 2019 , Article)Proper management of nonhealing wounds is an imperative clinical challenge. For the effective healing of chronic wounds, suitable wound coverage materials with the capability to accelerate cell migration, cell proliferation, ... -
Specific gene patterns and molecular pathways related to human carcinogenesis in different populations among various geographic locations.
( Wiley , 2016 , Other)We read with great interest the article by Beg et al,1 which was recently published in Cancer. Colorectal cancers (CRCs) are the most commonly diagnosed malignancies, accounting for approximately 1.36 million new cases ... -
Water-pipe smoking and serum testosterone levels in adult males in Qatar.
( European Publishing , 2019 , Article)Water-pipe (WP) smoking is the most common method of tobacco consumption in the Middle-East and is rapidly spreading on a global scale. Although, water-pipe smoking is linked to various diseases, such as emphysema and ... -
HER-2/Epstein-Barr virus crosstalk in human gastric carcinogenesis: A novel concept of oncogene/oncovirus interaction.
( Taylor & Francis , 2018 , Article)Gastric cancer is the fourth most common cancer and the second leading cause of cancer deaths worldwide. Additionally, it is well-known that metastatic cancer disease is a major cause of morbidity and mortality in cancer ... -
Epstein-Barr virus and its association with Fascin expression in colorectal cancers in the Syrian population: A tissue microarray study.
( Taylor & Francis , 2017 , Article)Colorectal cancer (CRC) is the third most common malignancy in both men and women worldwide. Colorectal carcinogenesis is a complex, multistep process involving environmental and lifestyle features as well as sequential ... -
Targeting triple negative breast cancer heterogeneity with chalcones: a molecular insight.
( Informa Healthcare , 2019 , Article Review)Triple negative breast cancers (TNBCs) are aggressive heterogeneous cancers with not yet determined conventional targeted medication. Therefore, identification of new alternatives or improved treatment options to combat ... -
Electrospun polyvinyl alcohol membranes incorporated with green synthesized silver nanoparticles for wound dressing applications.
( Springer Verlag , 2018 , Article)Electrospun membranes have the potential to act as an effective barrier for wounds from the external environment to prevent pathogens. In addition, materials with good antibacterial properties can effectively fight off the ... -
Urine tests for diagnosis of infectious diseases and antibiotic –resistant pathogens
( IntechOpen , 2019 , Book chapter)The relation between disease and urine was recognized by physicians since the earliest civilization BC. Urine is considered an ideal diagnostic specimen for its noninvasive and easy method of collection. Urinalysis encompasses ... -
Curcumin a Colorimetric and Fluorimetric Cyanide Probe in Aqueous System and Living Cells
( Royal Society of Chemistry , 2019 , Article)Curcumin, 1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-hepta-diene-3,5-dione, is a natural product obtained from the rhizome of Curcuma longa. Curcumin has been demonstrated to be a strong antioxidant with anticancer properties ...
