عرض بسيط للتسجيلة

المؤلفMutlu, Onur
المؤلفMazhar, Noaman
المؤلفSaribay, Murat
المؤلفYavuz, Mehmet Metin
المؤلفOzturk, Deniz
المؤلفGhareeb, Abdel Naser
المؤلفAlnabti, Abdulrahman
المؤلفYalcin, Huseyin Cagatay
تاريخ الإتاحة2025-04-08T05:04:30Z
تاريخ النشر2025-02-01
اسم المنشورJournal of Clinical Medicine
المعرّفhttp://dx.doi.org/10.3390/jcm14030850
الاقتباسMutlu, O.; Mazhar, N.; Saribay, M.; Yavuz, M.M.; Ozturk, D.; Ghareeb, A.N.; Alnabti, A.; Yalcin, H.C. Finite Element Analysis of Evolut Transcatheter Heart Valves: Effects of Aortic Geometries and Valve Sizes on Post-TAVI Wall Stresses and Deformations. J. Clin. Med. 2025, 14, 850. https://doi.org/10.3390/jcm14030850
معرّف المصادر الموحدhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85217628378&origin=inward
معرّف المصادر الموحدhttp://hdl.handle.net/10576/64052
الملخصBackground/Objectives: For transcatheter aortic valve implantation (TAVI) therapy, a catheter-guided crimped valve is deployed into the aortic root. Valve types such as Edwards balloon-expandable valves and Medtronic self-expandable valves come in different sizes and are chosen based on patient-specific aortic anatomy, including aortic root diameter measurement. Complications may arise due to variations in anatomical characteristics and the implantation procedure, making pre-implantation assessment important for predicting complications. Methods: Computational modeling, particularly finite element analysis (FEA), has become popular for assessing wall stresses and deformations in TAVI. In this study, a finite element model including the aorta, native leaflets, and TAVI device was used to simulate procedures and assess patient-specific wall stresses and deformations. Results: Using the Medtronic Evolut R valve, we simulated TAVI for 14 patients to analyze the effects of geometrical variations on structural stresses. Virtual TAVIs with different valve sizes were also simulated to study the influence of TAV size on stresses. Our results show that variations in aortic wall geometries and TAV sizes significantly influence wall stresses and deformations. Conclusions: Our study is one of the first comprehensive FEA investigations of aortic geometrical variations and valve sizes on post-TAVI stresses, demonstrating the non-linear relationship between aortic dimensions, TAV sizes, and wall stresses.
راعي المشروعThis work was funded by the Qatar National Research Fund (QNRF), National Priority Research Program (Grant number NPRP13S-0108-200024). Open-access funding was provided by the Qatar National Library.
اللغةen
الناشرMDPI
الموضوعABAQUS
aortic stenosis
contact pressure
Evolut-R
finite element analysis
transcatheter aortic valve implantation
von Mises stresses
العنوانFinite Element Analysis of Evolut Transcatheter Heart Valves: Effects of Aortic Geometries and Valve Sizes on Post-TAVI Wall Stresses and Deformations
النوعArticle
رقم العدد3
رقم المجلد14
ESSN2077-0383
dc.accessType Open Access


الملفات في هذه التسجيلة

Thumbnail

هذه التسجيلة تظهر في المجموعات التالية

عرض بسيط للتسجيلة