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AuthorLee, Sooji
AuthorSon, Yejun
AuthorHwang, Jiyoung
AuthorKim, Min Seo
AuthorShin, Jae Il
AuthorKassebaum, Nicholas J.
AuthorAbate, Semagn Mekonnen
AuthorAbate, Yohannes Habtegiorgis
AuthorElHafeez, Samar Abd
AuthorAbd-Elsalam, Sherief
AuthorAbdoun, Meriem
AuthorAbdulkader, Rizwan Suliankatchi
AuthorAbdullahi, Auwal
AuthorAbebe, Mesfin
AuthorAbedi, Armita
AuthorAbie, Alemwork
AuthorAbiodun, Olumide
AuthorAboagye, Richard Gyan
AuthorAbolhassani, Hassan
AuthorAbouzid, Mohamed
AuthorAbreu, Lucas Guimarães
AuthorAbualruz, Hasan
AuthorAbukhadijah, Hana J.
AuthorAburuz, Salahdein
AuthorAbu-Zaid, Ahmed
AuthorAdamu, Lawan Hassan
AuthorAdane, Mesafint Molla
AuthorAddo, Isaac Yeboah
AuthorAdegboye, Oyelola A.
AuthorAdekanmbi, Victor
AuthorAdetunji, Charles Oluwaseun
AuthorAdeyeoluwa, Temitayo Esther
AuthorAdnani, Qorinah Estiningtyas Sakilah
AuthorAdzigbli, Leticia Akua
AuthorAfzal, Saira
AuthorAgampodi, Suneth Buddhika
AuthorAgyemang-Duah, Williams
AuthorAhmad, Aqeel
AuthorAhmad, Muayyad M.
AuthorAhmad, Shahzaib
AuthorAhmad, Tauseef
AuthorAhmed, Ali
AuthorAhmed, Ayman
AuthorAhmed, Haroon
AuthorAhmed, Mehrunnisha Sharif
AuthorAhmed, Syed Anees
AuthorAjami, Marjan
AuthorAkinosoglou, Karolina
AuthorAkter, Ema
AuthorAwaidy, Salah Al
AuthorHasan, Syed Mahfuz Al
AuthorOmari, Omar Al
AuthorAlajlani, Muaaz M.
AuthorAl-Aly, Ziyad
AuthorAl-amer, Rasmieh Mustafa
AuthorAlbashtawy, Mohammed
AuthorAldhaleei, Wafa A.
AuthorAlgammal, Abdelazeem M.
AuthorAlhalaiqa, Fadwa Naji
AuthorAli, Abid
AuthorAli, Akhtar
AuthorAli, Liaqat
AuthorAli, Mohammed Usman
AuthorAli, Syed Shujait
AuthorAli, Waad
AuthorSamakkhah, Shohreh Alian
AuthorAlif, Sheikh Mohammad
AuthorAl-Marwani, Sabah
AuthorAl-Mekhlafi, Hesham M.
AuthorAlmustanyir, Sami
AuthorAlqahtani, Jaber S.
AuthorMohammad Al-Raddadi, Rajaa M.
AuthorAlsabri, Mohammed A.
AuthorAltaany, Zaid
AuthorAltaf, Awais
AuthorAl-Tammemi, Alaa B.
AuthorAltirkawi, Khalid A.
AuthorAly, Hany
AuthorAlzoubi, Karem H.
AuthorAmani, Reza
AuthorAmiri, Sohrab
AuthorAmu, Hubert
AuthorAmusa, Ganiyu Adeniyi
AuthorAncuceanu, Robert
AuthorAndrei, Tudorel
AuthorAnuoluwa, Boluwatife Stephen
AuthorAnuoluwa, Iyadunni Adesola
AuthorAnvari, Saeid
AuthorAnwar, Sumadi Lukman
AuthorAnyasodor, Anayochukwu Edward
AuthorArabloo, Jalal
AuthorArafat, Mosab
AuthorAravkin, Aleksandr Y.
AuthorAreda, Demelash
AuthorAregawi, Brhane Berhe
AuthorAremu, Abdulfatai
AuthorAriffin, Hany
AuthorArkew, Mesay
AuthorAryastami, Ni Ketut
AuthorAshemo, Mubarek Yesse
AuthorAtata, Jamila Abdulhamid
AuthorAthari, Seyyed Shamsadin
AuthorWahbi Atout, Maha Moh'd
AuthorAtreya, Alok
AuthorAweke, Amlaku Mulat
AuthorAwoke, Mamaru Ayenew
AuthorQuintanilla, Beatriz Paulina Ayala
AuthorAzhar, Gulrez Shah
AuthorAzzam, Ahmed Y.
AuthorBabu, Giridhara Rathnaiah
AuthorBaghcheghi, Nayereh
AuthorBagheri, Nasser
AuthorBahramian, Saeed
AuthorBaig, Atif Amin
AuthorBakkannavar, Shankar M.
AuthorBalakrishnan, Senthilkumar
AuthorBalcha, Wondu Feyisa
AuthorBanik, Palash Chandra
AuthorBansal, Hansi
AuthorBante, Simachew Animen
AuthorBasiru, Afisu
AuthorBastan, Mohammad-Mahdi
AuthorBatra, Kavita
AuthorBegum, Tahmina
AuthorBello, Muhammad Bashir
AuthorBelo, Luis
AuthorBensenor, Isabela M.
AuthorBeressa, Girma
AuthorBerhie, Alemshet Yirga
AuthorBhagat, Devidas S.
AuthorBhala, Neeraj
AuthorBhardwaj, Nikha
AuthorBhardwaj, Pankaj
AuthorBhardwaj, Prarthna V.
AuthorBhaskar, Sonu
AuthorBhat, Ajay Nagesh
AuthorBhatti, Jasvinder Singh
AuthorBiswas, Bijit
AuthorBodhare, Trupti
AuthorBodunrin, Aadam Olalekan
AuthorBoloor, Archith
AuthorBora, Kaustubh
AuthorBorhany, Hamed
AuthorBouaoud, Souad
AuthorBustanji, Yasser
AuthorBarsbay, Mehtap Çakmak
AuthorCalina, Daniela
AuthorCámera, Luis Alberto
AuthorCao, Fan
AuthorCattafesta, Monica
AuthorCegolon, Luca
AuthorCembranel, Francieli
AuthorCenderadewi, Muthia
AuthorCercy, Kelly M.
AuthorChakraborty, Chiranjib
AuthorChakraborty, Sandip
AuthorChandika, Rama Mohan
AuthorChattu, Vijay Kumar
AuthorChaurasia, Akhilanand
AuthorChen, Haowei
AuthorChi, Gerald
AuthorChing, Patrick R.
AuthorChirinos-Caceres, Jesus Lorenzo
AuthorCho, William C. S.
AuthorChong, Bryan
AuthorChopra, Hitesh
AuthorChoudhari, Sonali Gajanan
AuthorChu, Dinh-Toi
AuthorChukwu, Isaac Sunday
AuthorConcina, Federica
AuthorCriqui, Michael H.
AuthorCruz-Martins, Natalia
AuthorGomes da Silva, Alanna
AuthorDadras, Omid
AuthorD'Amico, Emanuele
AuthorDarcho, Samuel Demissie
AuthorDas, Saswati
AuthorDash, Nihar Ranjan
AuthorDebopadhaya, Shayom
AuthorBo', Cristian Del
AuthorDelgado-Enciso, Ivan
AuthorDesai, Hardik Dineshbhai
AuthorDesta, Fikreab
AuthorDevegowda, Devananda
AuthorDhane, Amol S.
AuthorDhulipala, Vishal R.
AuthorDo, Thanh Chi
AuthorDo, Thao Huynh Phuong
AuthorDoaei, Saeid
AuthorDohare, Sushil
AuthorD'Oria, Mario
AuthorDoshi, Ojas Prakashbhai
AuthorDowou, Robert Kokou
AuthorDsouza, Ashel Chelsea
AuthorDsouza, Haneil Larson
AuthorDuraisamy, Senbagam
AuthorDutta, Sulagna
AuthorEdinur, Hisham Atan
AuthorEfendi, Ferry
AuthorEftekharimehrabad, Aziz
AuthorEghbali, Foolad
AuthorEkholuenetale, Michael
AuthorBayoumy, Ibrahim Farahat El
AuthorElbarazi, Iffat
AuthorElGohary, Ghada Metwally Tawfik
AuthorElhadi, Muhammed
AuthorEl-Huneidi, Waseem
AuthorElshaer, Mohammed
AuthorElsohaby, Ibrahim
AuthorEmeto, Theophilus I.
AuthorFagbamigbe, Adeniyi Francis
AuthorFahim, Ayesha
AuthorFakhradiyev, Ildar Ravisovich
AuthorFaris, MoezAlIslam Ezzat Mahmoud
AuthorFauk, Nelsensius Klau
AuthorFazeli, Patrick
AuthorFeizkhah, Alireza
AuthorFekadu, Ginenus
AuthorFerreira, Nuno
AuthorFischer, Florian
AuthorFlorin, Bobirca Teodor
AuthorFolayan, Morenike Oluwatoyin Oluwátóyìn
AuthorFomenkov, Artem Alekseevich
AuthorFukumoto, Takeshi
AuthorFux, Blima
AuthorSridevi, G.
AuthorGadanya, Muktar A.
AuthorGaidhane, Abhay Motiramji
AuthorGalali, Yaseen
AuthorGandhi, Aravind P.
AuthorGardner, William M.
AuthorGautam, Rupesh K.
AuthorGebregergis, Miglas Welay
AuthorGebrehiwot, Mesfin
AuthorGebremariam, Tesfay B. B.
AuthorGeremew, Habtamu
AuthorGetacher, Lemma
AuthorGetahun, Genanew K.
AuthorGetie, Molla
AuthorGetie, Simegnew Asmer
AuthorGhadimi, Delaram J.
AuthorGhailan, Khalid Yaser
AuthorGhazy, Ramy Mohamed
AuthorGholamalizadeh, Maryam
AuthorGholamrezanezhad, Ali
AuthorGil, Artyom Urievich
AuthorGiri, Bikash Ranjan
AuthorGirmay, Alem Abera
AuthorGoulart, Alessandra C.
AuthorGubari, Mohammed Ibrahim Mohialdeen
AuthorGunawardane, Damitha Asanga
AuthorGupta, Anish Kumar
AuthorGupta, Ishita
AuthorGupta, Rajat Das
AuthorGupta, Sapna
AuthorGupta, Vivek Kumar
AuthorHabibzadeh, Farrokh
AuthorHabibzadeh, Parham
AuthorHadi, Najah R.
AuthorHagins, Hailey
AuthorHalim, Sobia Ahsan
AuthorHamdy, Nadia M.
AuthorHamidi, Samer
AuthorHandal, Alexis J.
AuthorHandiso, Demelash Woldeyohannes
AuthorHasaballah, Ahmed I.
AuthorHasan, Md. Kamrul
AuthorHasani, Hamidreza
AuthorHasnain, Md Saquib
AuthorHassan, Ikrama Ibrahim
AuthorHassankhani, Hadi
AuthorHay, Simon I.
AuthorHayat, Khezar
AuthorHeidari, Golnaz
AuthorHemmati, Mehdi
AuthorHezam, Kamal
AuthorHiraike, Yuta
AuthorHoan, Nguyen Quoc
AuthorHolla, Ramesh
AuthorHossain, Md Mahbub
AuthorHosseinzadeh, Mehdi
AuthorHostiuc, Mihaela
AuthorHostiuc, Sorin
AuthorHuang, Junjie
AuthorHundie, Tsegaye Gebreyes
AuthorHussain, Javid
AuthorHuynh, Hong-Han
AuthorHwang, Bing-Fang
AuthorIbitoye, Segun Emmanuel
AuthorIkeda, Nayu
AuthorIlesanmi, Olayinka Stephen
AuthorIlic, Irena M.
AuthorIlic, Milena D.
AuthorImmurana, Mustapha
AuthorInbaraj, Leeberk Raja
AuthorInok, Arit
AuthorIqhrammullah, Muhammad
AuthorIrham, Lalu Muhammad
AuthorIslam, Md. Rabiul
Available date2025-05-25T06:32:47Z
Publication Date2025-04-22
Publication NameNature Medicine
Identifierhttp://dx.doi.org/10.1038/s41591-025-03624-8
ISSN1078-8956
URIhttp://hdl.handle.net/10576/65140
AbstractAlthough iron deficiency is well documented, less is known about dietary involvement in symptomatic iron deficiency manifesting in medical conditions. In this study, we quantified the global burden of dietary iron deficiency, focusing on where inadequate dietary iron intake leads to clinical manifestations such as anemia. We analyzed data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 to estimate dietary iron deficiency prevalence and disability-adjusted life years (DALYs), stratified by age, sex, geography and socio-demographic index (SDI) across 204 countries. In 2021, global age-standardized prevalence and DALY rates were 16,434.4 (95% uncertainty interval (UI), 16,186.2-16,689.0) and 423.7 (285.3-610.8) per 100,000 population, with rates decreasing by 9.8% (8.1-11.3) and 18.2% (15.4-21.1) from 1990 to 2021. A higher burden was observed in female individual (age-standardized prevalence, 21,334.8 (95% UI, 20,984.8-21,697.4); DALYs, 598.0 (402.6-854.4)) than in male individual ((age-standardized prevalence, 11,684.7 (11,374.6-12,008.8); DALYs, 253.0 (167.3-371.0)). High-SDI countries presented greater improvement, with a 25.7% reduction compared to 11.5% in low-SDI countries. Despite global improvements, dietary iron deficiency remains a major health concern with a global prevalence of 16.7%, particularly affecting female individuals, children and residents in low-SDI countries. Urgent interventions through supplementation, food security measures and fortification initiatives are essential.
SponsorThis study was funded by the Bill and Melinda Gates Foundation, the Australian National Health and Medical Research Council and the Queensland Department of Health, Australia. This work was supported by the Yonsei Fellowship, funded by Lee Youn Jae (J.I.S.). This research was supported by the Ministry of Science and ICT (MIST), Korea, under the Information Technology Research Center (ITRC) support program (IITP-2024-RS-2024-00438239 to D.K.Y.), supervised by the Institute for Information & Communications Technology Planning & Evaluation (IITP). The funders of the study had no role in study design, data collection, data analysis, data interpretation or writing of the report. All authors had full access to the study data and had final responsibility for the decision to submit for publication.
Languageen
PublisherWiley
SubjectIron Deficiency-Dietary Factors
Anemia-Epidemiology
Global Health - Nutritional Deficiencies
Disability-Adjusted Life Years (DALYs)
Socioeconomic Factors - Health Disparities
TitleGlobal, regional and national burden of dietary iron deficiency from 1990 to 2021: a Global Burden of Disease study.
TypeArticle
ESSN1546-170X
dc.accessType Full Text


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