Laboratory Animal Research Center: Recent submissions

Now showing items 101-108 of 108

    • Diagnostic Microbiology Laboratory Monitoring of LARC 

      Khan, Imran; Shanmugakonar, Muralitharan; Aboujassoum, Hamda; Al Naemi, Hamda (2017 , Poster)
      Microbial free environment of a research facility is critical to maintain animal health. Establishing Microbiological Monitoring Program is mandatory to assure the quality of the system. Microbiological monitoring involves ...

    • Environmental Health Monitoring Program (EHMP) of LARC 

      Shanmugakonar, Muralitharan; Abujassoum, Hamda; Khan, Imran; Al Naemi, Hamda (2017 , Poster)
      Routine environmental monitoring is the prime necessity to maintain a Specific Pathogen Free (SPF) facility. Monitoring the animals & its environment is important to control the contamination and outbreak of disease. ...

    • ANIMAL MODEL FOR CHILDHOOD OBESITY 

      Al-Naemi, Hamda; Das, Sandra Concepcion (2017 , Poster)
      Obesity has been recognized as a global health problem and linked with chronic diseases such as diabetes mellitus, cardiovascular syndromes, musculoskeletal disorders and some cancers. Children exposed to high carbohydrate, ...

    • Effect of CARMA 2sh gene in Mouse embryonic stem (ES) cells 

      Shanmugakonar, Muralitharan; Varadharajan, Kavitha; Vito, Pasquale (2017 , Poster)
      CARMA2 belongs to the CARMA family of proteins. They are involved in the regulation and activation of NF-κB that have a central role in the control of immune and inflammatory response, and cell survival and proliferation. ...

    • ENDOTHELIAL NITRIC OXIDE ACTIVITY & BIOAVAILABILITY DURING OBESITY CONDITIONS 

      Das, Sandra Concepcion; Al-Naemi, Hamda (2017 , Poster)
      Obesity has been recognized as a pandemic and linked with several metabolic dysfunctions. One of the hallmarks in the onset of obesity is the development of hypertension coupled with endothelial dysfunction. (ED) A fundamental ...

    • CARMA2sh and ULK2 control pathogen-associated molecular patterns recognition in human keratinocytes: psoriasis-linked CARMA2sh mutants escape ULK2 censorship 

      Scudiero, Ivan; Mazzone, Pellegrino; D'Andrea, Luca E.; Ferravante, Angela; Zotti, Tiziana; ... more authors ( Nature , 2017 , Article)
      The molecular complexes formed by specific members of the family of CARMA proteins, the CARD domain-containing adapter molecule BCL10 and MALT1 (CBM complex) represent a central hub in regulating activation of the pleiotropic ...

    • Expression of active and inactive forms of CIK and CARMA 2sh proteins in Normal Human Epidermal Keratinocytes (NHEK) 

      Shanmugakonar, Muralitharan; Varadharajan, Kavitha; Vito, Pasquale (2016 , Poster)
      Psoriasis is a debilitating skin disease affecting approximately 23% of human population. The disease is considered to have key genetic underpinning and genome wide association studies and meta analysis have identified ...

    • NF-κB Essential MOdulator (NEMO) Is Critical for Thyroid Function 

      Reale, Carla; Iervolino, Anna; Scudiero, Ivan; Ferravante, Angela; Egildo D, Luca; ... more authors ( American Society for Biochemistry and Molecular Biology , 2016 , Article)
      The I-κB kinase (IKK) subunit NEMO/IKKγ (NEMO) is an adapter molecule that is critical for canonical activation of NF-κB, a pleiotropic transcription factor controlling immunity, differentiation, cell growth, tumorigenesis ...