Apocrine Carcinoma
| Author | Vranic, Semir |
| Author | Gatalica, Zoran |
| Available date | 2019-04-08T11:30:07Z |
| Publication Date | 2017-12-11 |
| Publication Name | Encyclopedia of Pathology |
| Identifier | http://dx.doi.org/10.1007/978-3-319-28845-1_4693-1 |
| Citation | Vranic S., Gatalica Z. (2018) Apocrine Carcinoma. In: van Krieken J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham |
| ISBN | 978-3-319-28845-1 |
| Abstract | Carcinoma with apocrine differentiation (invasive apocrine carcinoma) is defined by “WHO Classification of Tumours of the Breast” as “any invasive carcinoma in which cells show the cytological features of apocrine cells” (O’Malley and Lakhani 2012). More strictly, it is a breast cancer characterized by apocrine morphology (abundant eosinophilic and granular cytoplasm, centrally/eccentrically located nuclei with prominent nucleoli and distinct cell borders) and a distinct steroid receptor profile: Estrogen receptor (ER)-negative and androgen receptor (AR)- positive cells (Vranic et al. 2013). |
| Language | en |
| Publisher | Springer, Cham |
| Subject | Breast cancer Apocrine carcinoma Androgen receptor HER2 Carcinoma with apocrine differentiation Invasive apocrine carcinoma |
| Type | Book chapter |
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