Apocrine Carcinoma
Author | Vranic, Semir |
Author | Gatalica, Zoran |
Available date | 2019-12-23T08:55:07Z |
Publication Date | 2020-01-01 |
Publication Name | Breast Pathology |
Identifier | http://dx.doi.org/10.1007/978-3-319-62539-3 |
Citation | Vranic S., Gatalica Z. (2020) Apocrine Carcinoma. In: Sapino A., Kulka J. (eds) Breast Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-62539-3 |
ISBN | 978-3-319-62539-3 |
Abstract | Carcinoma with apocrine differentiation (invasive apocrine carcinoma) is defined by “WHO Classification of Tumours of the Breast” as “any invasive carcinoma in which cells show the cytological features of apocrine cells” (O’Malley and Lakhani 2012). More strictly, it is a breast cancer characterized by apocrine morphology (abundant eosinophilic and granular cytoplasm, centrally/eccentrically located nuclei with prominent nucleoli and distinct cell borders) and a distinct steroid receptor profile: Estrogen receptor (ER)-negative and androgen receptor (AR)-positive cells . |
Language | en |
Publisher | Springer |
Subject | breast cancer pathology special types apocrine carcinoma |
Type | Book chapter |
Pagination | 29 - 33 |
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Medicine Research [1418 items ]